Term
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Definition
Secreted by G cells in stomach
promotes gastric acid secretion, gastric mucosa growth and stomach motility
Binds to CCK-b receptors |
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Term
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Definition
secreted from I cells in SI
secreted in response to fat, FA and monoglycerides present
contracts gall bladder, relaxes hepatopancreatic sphincter, inhibits stomach contraction and over eating |
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Term
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Definition
Secreted by enterochromaffin S cells in SI
stimulates pepsin, pancreatic and biliary bicarb secretion. inhibits gastric acid secretion |
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Term
| gastric inhibitory peptide (GIP) |
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Definition
secreted by epithelial cells in upper SI
released due to increase in fat, AA and carbs
inhibits stomach motility and screcetion. stimulates release of insulin, is glucose-dependent insulinotropic peptide |
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Term
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Definition
produced by M cells in stomach and upper SI during fasting
stimulates GI motility waves called interdigestive myoelectric complexes |
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Term
| vasoactive intestinal polypeptide (VIP) |
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Definition
secreted by enteric neurons in SI
is a neuropeptide/transmitter. distributed in peripheral and central NS
induces intestinal vasodilation, and intestinal secretion. relaxes smooth muscles in trachea, stomach gall bladder and sphincters and HCL secretion |
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Term
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Definition
released in stomach, pituitary and hypothalamus
causes an increases in hunger. controls hunger
levels are low after eating and usually in obese people. levels high in anorexia nervosa pts. |
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Term
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Definition
extreme obesity due to an uncrontrolled appetite
ghrelin levels are really high in these individuals |
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Term
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Definition
released by the L cells in SI and LI
stimulates insulin release satiety |
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Term
| drugs that decrease vagal tone (parasympathetic tine) |
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Definition
| atropine, scopolamine, antihistamines, Tricyclic antidepressants, neuroleptics |
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Term
| drugs that increase vagal tone that induce bowl contraction(parasympathetic tine) |
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Definition
| Bethanechol and neostigmine |
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Term
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Definition
tegaserod
metoclopramide
cisapride
this increase the release of ACh |
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Term
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Definition
ondansetrone and derivatices
anti-emetic and analgesic |
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Term
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Definition
| increases intestinal secretion and peristalisis |
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Term
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Definition
| inhibits secretion of GI hormones and VIP |
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Term
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Definition
| stimulates gastric and pancreatic secretion |
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Term
| AVP (ADH) receptor antagonist Used for hypotonic hypoNa |
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Definition
conivaptan
tolvaptan
ADR- thirst headache, vomiting |
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