| Term 
 
        | heartburn abdominal pain
 dyspepsia - upset stomach
 nausea
 vomiting
 diarrhea
 constipation
 gastrointestinal bleeding - melena (upper GI bleed, dark/tarry stools); hematochezia (lower GI bleed)
 itching - symptom of hepatobiliary disease, itching of palms of hands and/or soles of feet
 |  | Definition 
 
        | common symptoms associated with GI disorders |  | 
        |  | 
        
        | Term 
 
        | patient history is the cornerstone of GI evaluation 
 should be detailed and chronological
 
 use OLDCARTS during interview
 
 discuss dietary habits
 
 weight changes
 
 travel outside of US
 
 family history of GI disorders
 
 medication history
 |  | Definition 
 
        | patient history that should be obtained when interviewing about GI disorders |  | 
        |  | 
        
        | Term 
 
        | injury to GI mucosa: 
 ASA/NSAIDs
 bisphosphonates
 corticosteroids
 alcohol
 warfarin (no injury to GI mucosa, but it injured patient is more likely to bleed)
 chemotherapy
 iron
 
 cause liver damage:
 
 APAP
 amiodarone
 statins
 methyldopa
 PTU
 interferon beta
 duloxetine
 
 diarrhea, GI symptoms:
 
 antibiotics
 |  | Definition 
 
        | medications that may cause GI injury |  | 
        |  | 
        
        | Term 
 
        | assess organ function 
 screen for certain GI disorders
 
 evaluate effectiveness of therapy
 |  | Definition 
 
        | reasons for lab testing in GI disorders |  | 
        |  | 
        
        | Term 
 
        | CBC: WBC - infection, malignancy
 Hgb/Hct - possible blood loss, anemias
 PLT - risk of bleeding, malignancy, liver disease
 
 serum chemistry panel (BMP, Chem 7):
 BUN and SCr - hypdration status, renal function
 Na, Cl, K - electrolyte abnormalities from diarrheal illnessess
 
 liver function tests (LFTs):
 PTT and INR (clotting factors made in the liver)- hepatic disease
 albumin - hepatic or renal disease
 alkaline phosphatase and bilirubin - hepatobiliary disease
 
 measure of liver damage:
 ALT and AST (byproduct of cell damage) - liver disease (end stage liver disease, these may be low b/c the liver is so damaged that ALT/AST cannot be produced any more)
 
 amylase and lipase - pancreatic illness
 
 microbiology - stool studies for infectious diarrhea or H. pylori infection
 |  | Definition 
 
        | lab testing for GI disorders |  | 
        |  | 
        
        | Term 
 
        | plain x-ray:  bowel obstruction and perforation 
 x-ray with contrast:
 barium sulfate usually used - unabsorbably; constipation most common ADR
 used to identify mucosal lesions, hiatal hernias, strictures, polyps, tumors, ulcers
 |  | Definition 
 
        | use of an x-ray in evaluating GI disorders |  | 
        |  | 
        
        | Term 
 
        | upper GI series:  radiographic visualization of the esophagus, stomach, small intestine 
 observe swallowing of contrast agent - esophageal structure and function
 
 small bowel follow-through - gastric cancer, PUD, esophagitis, gastric outlet obstruction, Crohn's disease
 
 low sensitivity and sepcificity
 
 PATIENT EDUCATION:  no eating/drinking 8-12 hours prior to test
 |  | Definition 
 
        | use of an upper GI series in evaluating GI disorders, patient education |  | 
        |  | 
        
        | Term 
 
        | lower GI series:  radiographic visualization of the colon and rectum 
 barium enema given during procedure
 
 detects obstructions and lesions
 
 diagnosis of Crohn's disease, ulcerative colitis, colon cancers, and diverticulitis
 
 PATIENT EDUCATION:  no eating/drinking 8-12 hours prior to test; bowel cleansing agents administered prior to test
 |  | Definition 
 
        | use of a lower GI series in evaluating GI disorders, patient education |  | 
        |  | 
        
        | Term 
 
        | ultrasonography can be used to visualize the gallbladder, liver, pancreas, abdominal wall 
 differences in reflection of sound waves
 
 can identify gallstones, hepatobiliary and pancreatic diseases
 
 limited by bowel gas and excessive body fat
 |  | Definition 
 
        | use of ultrasonography in evaluating GI disorders |  | 
        |  | 
        
        | Term 
 
        | transverse planes of tissue by radiographic beam and computer analysis produces a precise reconstructed image 
 contrast agents may be used
 
 detects disease of liver, pancreas, spleen, colon (liver cancer, pancreatitis, pancreatic cancer, abscesses, cysts)
 
 PATIENT EDUCATION:
 
 no eating/drinking x4h before
 
 have to drink a lot of water after administration of IV contrast agents to avoid kidney damage
 
 metformin:
 patients should stop taking metformin the day of the procedure and 48 hours afterward
 get a baseline SCr and a SCr 48h after administration of IV contrast to evaluate renal status
 |  | Definition 
 
        | use of computed tomography (CT) or computed axial tomography (CAT) in evaluating GI disorders, patient education |  | 
        |  | 
        
        | Term 
 
        | radiofrequency signals forming a 2-dimensional image 
 greatest sensitivity for liver tumors
 |  | Definition 
 
        | use of magnetic resonance imaging (MRI) in the evaluation of GI disorders |  | 
        |  | 
        
        | Term 
 
        | illuminated optical instrument to inspect the interior of GI tract 
 inspect intraluminal mucosal lesions and obtain biopsies and washings for cytology studies
 
 common indications:  evaluating suspected GI bleed, obstructions, upper abdominal pain, infections (C. difficile colitis), malignancies, colonic lesions, colonic polyps
 
 "conscious sedation" used for procedures
 
 contraindicated for patients w/ severe respiratory distress or cardiac failure
 
 many types:
 esophagogastroduodenoscopy (EGD) - visualizes upper GI tract up to the duodenum
 colonoscopy
 sigmoidoscopy
 endoscopic retrograde cholangiopancreatography (ERCP) - inspect pancreas if gallstones as suspected
 capsule endoscopy - patient swallows a capsule that has a camera in it
 
 PATIENT EDUCATION:
 
 no eating/drinking x8-12h prior
 
 bowel prep and cleansing prior to colonoscopy or sigmoidoscopy
 |  | Definition 
 
        | use of an endoscopy for evaluation of GI disorders, patient education |  | 
        |  | 
        
        | Term 
 
        | ultrasonography computed tomography (CT) or computed axial tomography (CAT)
 magnetic resonance imaging (MRI)
 endoscopy
 |  | Definition 
 
        | examples of imaging studies to evaluate the GI tract |  | 
        |  | 
        
        | Term 
 
        | plain x-ray x-ray with contrast
 upper GI series
 lower GI series
 |  | Definition 
 
        | examples of radiology used to study the GI tract |  | 
        |  |