Term
What are the major Irritants used as laxatives?
What are the adverse effects of each? |
|
Definition
Irritant Laxatives
Castor Oil- GI bleeding
Phenolphthalein
Bisacodyl- Colon bleeding |
|
|
Term
| What is the mechanism of castor oil? |
|
Definition
| Ricinoleic Acid irritates the colon to increase motility |
|
|
Term
What is the mechanism of stool bulking agents?
What are the common ones?
What are the adverse effects? |
|
Definition
Mech: Absorbs interstitial water of the colon
Hydrophilic Colloids
Bran
Adverse: Obstruction and Bleeding
|
|
|
Term
What is the mechanism of stool softeners?
When is it used?
What are the common ones? |
|
Definition
Mech: Emulsify the stool
Use: Post-Op from Hemerrhoid/Fistula Bleeding and geriatric patients
Stool Softeners
Docusate(colace)
Mineral oil
|
|
|
Term
What is the mechanism of osmotic Laxatives?
What is the use?
What are common agents? |
|
Definition
Mech: Hypertonic solution draging water
Use: Cleansing the bowel for colonoscopy
Magnesium Hydroxide
Magnesium Citrate
Lactulose
Polyethylene Glycol |
|
|
Term
What is the major Anti-diarrheals?
What is the mechanism of each?
What are the adverse reactions of each? |
|
Definition
Diphenoxylate: Metabolism to Meperidine given with atropine to prevent abuse
Adverse: Abuse
Loperamide: Narcotic not absorbed systemically
Adverse: 24 hr delay-Potential for overdose constipation
Bismuth Subsalicylate |
|
|
