Term
What are the H2 blockers?
What is their mechanism? |
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Definition
Cimetidine
Ranitidine
Famotidine
Nizatidine
Take H2 blockers before you DINE
"Table for 2"
Reversible block of histamine H2 receptors → ↓ H+ secretion by parietal cells |
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Term
| What drugs reversibly block histamine H2 receptors → ↓ H+ secretion by parietal cells? |
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Definition
H2 Blockers
Cimetidine
Ranitidine
Famotidine
Nizatidine |
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Term
| What H2 Blocker is a potent P-450 inhibitor and has antiandrogenic effects that can lead to gynecomastia? |
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Definition
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Term
| What H2 blockers can decrease renal exceretion of creatinine? |
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Definition
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Term
| What drugs irreversibly inhibit H+/K+-ATPase in stomach parietal cells? |
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Definition
Proton Pump Inhibitors
Omeprazole
Lansoprazole |
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Term
| What Drugs bind to ulcer base, providing physical protection, and allow HCO3- secretion to reestablish pH gradient in the mucous layer? |
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Definition
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Term
What drugs can be used to treat and prevent Traveler's diarrhea?
(Enterotoxogenic E. coli) |
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Definition
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Term
| What drug is a PGE1 analog that increases production and secretion of gastric mucous barrier and decreases acid production? |
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Definition
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Term
| What drug is used to prevent NSAID-induced peptic ulcers? |
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Definition
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Term
| What drug can be used to maintain patent ductus arteriosus? |
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Definition
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Term
| What drug is contraindicated in women of childbearing potential? why? |
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Definition
Misoprostol
Abortifacient |
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Term
| What drug is a Long-acting somatostatin analog used to treat variceal bleeds, acromegaly, VIPomas, and carcinoid tumors? |
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Definition
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Term
| What drug can cause Nausea, Cramps, and steatorrhea with toxicity? |
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Definition
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Term
| What Antacid can cause constipation and hypophosphatemia? |
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Definition
Aluminum hydroxide
can also cause proximal muscle weakness, osteodystrophy, and seizures |
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Term
| What antacid can cause diarrhea, hyporeflexia, hypotension, and cardiac arrest? |
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Definition
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Term
| What antacid can cause rebound acid increase? |
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Definition
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Term
| What osmotic laxative can treat hepatic encephalopathy because its metabolites promote nitrogen excretion as NH4+? |
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Definition
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Term
| What monoclonal antibody to TNF is used to treat Crohn's disease and rheumatoid arthritis? |
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Definition
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Term
What drug is a combination of sulfapyridine (antibacterial) and 5-ASA (anti-inflammatory)?
How does it work? |
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Definition
Sulfasalazine
Becomes activated by colonic bacteria
to treat UC and Crohn's disease |
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Term
| What drug is a 5-HT3 antagonist used to treat nausea/vomiting? |
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Definition
Ondansetron
Powerful central-acting antiemetic |
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Term
| What drug can be used to increase resting tone, contractility, LES tone, and motility of GI? |
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Definition
D2 receptor antagonist
Metoclopramide |
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