Term
What gene is associated with Crohn disease
What people are affected? |
|
Definition
NOD2 on chromosome 16
15-25 or 55-60 White Jewish Smokers
|
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|
Term
| What infectious disease decreases the symptoms of IBD |
|
Definition
|
|
Term
| What is the histology of Active and Chronic Crohn Disease |
|
Definition
Active:
Cryptitis
Crypt Absesses
Ulcerations
Chronic
Atrophy
Branching Crypts
Metaplasia
Fibrosis
Granulomas |
|
|
Term
| What are Pseudopolyps and which IBD are they seen in? |
|
Definition
Chronic atrophy of surrouding tissue making healthy tissue appear polyp shaped
Seen in both Crohn and Ulcerative Colitis |
|
|
Term
| Extraintestinal manifestations of IBD? |
|
Definition
Ankylosing Spondilitis
Migrating Large Joint Arthritis
Erythema Nodosum
Pyoderma Gangrenosum
Aphthous Ulcers
Episcleritis and Uveitis
Primary Sclerosing Cholangitis(UC) |
|
|
Term
What is the only time a perforation will be seen in ulcerative colitis
When can Ulcerative colitis affect the ileum |
|
Definition
Toxic Megacolon
Affects Ileum in some cases of pancolitis |
|
|
Term
| Which IBD had the greater risk of colon cancer |
|
Definition
|
|
Term
What are the major differences between Crohn disease and Ulcerative colitis based on?
Distribution
Location
Depth of damage
Extent of Fibrosis
Granulomas
Fistulas/Sinuses
Fat Malabsorption
Malignancy
Recurrance
Toxic Megacolon |
|
Definition
|
|
Term
What people typically get Collagenous Colitis and what is the pathology
What is the other microscopic colitis? |
|
Definition
Women 40-70 with chronic watery stools
Focal Subepithelial Fibrosis
Other: Lymphocytic colitis |
|
|
Term
What structural features allow for diverticular formation
Where do diverticuli typically occur?
What are the signs of Diverticulitis |
|
Definition
Structural: Vasa Recta and Teniae Coli
Location: Sigmoid Colon
Diverticulitis:
Fever
Leukocytosis(increased WBC's)
Peritoneal pain |
|
|
Term
| What are Hemorrhoids and common causes |
|
Definition
Variceal Dilations of anal and Perianal Venous Plexuses
Causes: Pregnancy, Straining, Portal HPTN |
|
|
Term
What is Angiodyplasia?
How does it Occur?
Where is it most likely found |
|
Definition
Dilated mucosal and submucosal vessels
How: Blockage of venous drainage
Location: Cecum and Ascending Colon |
|
|
Term
| Most common tumor of the appendix |
|
Definition
|
|
Term
| What are the common causes of Appendicitis |
|
Definition
| Obstruction(fecalith, gallstone, worm, tumor) |
|
|
Term
| What is a Psuedomyxoma Peritoneii |
|
Definition
| Implantation of a mucus producing tumor from the appendix on the peritoneal wall |
|
|
Term
| What are the most common locations for a GIT carcinoid tumor |
|
Definition
|
|
Term
What are the signs of Carcinoid Syndrome
and what is required about the location to produce this syndrome |
|
Definition
Vasomotor problems: Flushing
Intestinal Hypermotility
Asthmatic attacks: Bronchoconstriction
Fibrosis Pulmonic and Tricuspid valves
Requirement: Bypass Hepatic Circulation |
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