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Details

GI-Path
Pathology of the Stomach
21
Pathology
Graduate
02/08/2011

Additional Pathology Flashcards

 


 

Cards

Term
What is the difference between Omphalocele and gastroschisis?
Definition
Omphalocele remains within the umbilical cord
Term

What is the cause of severe Post-Prandial Projectile Vomiting in an infant?

How is the condition treated?

Definition

Infantile Hypertrophic Pyloric Stenosis

Tx: Spliting the circular pyloric muscle

Term
Where in the stomach is there most likely to be a heterotrophic pancreas?
Definition
Antrum>Pyloris
Term
When is a gastritis considered a gastropathy
Definition
Damage or loss of epithelium
Term
What is the appearance of an atrophic gastritis
Definition
A reduction in the cell number and flattening of the gastric epithelium
Term

What does activity mean in describing gastritis?

Does activity occur in chronic or acute gastritis

Definition

Neutrophil infiltrate

Activity can occur in either Chronic or Acute gastritis

Term
What is the distinction between a gastric erosion and a ulcer
Definition
Ulcers extend below the mucosal lining
Term

What are the differences between Autoimmune gastritis and H.pylori caused gastritis

Which causes gland atrophy?

How do they differ by location?

Definition

Autoimmune: Body and fundus, Atrophic

H.Pylori: Antrum, Nonatrophic

Term

What is the histology of Autoimmune Gastritis?

What are some complications of Autoimmune gastritis

Definition

Histology:

Endocrine Hyperplasia

Parietal cell loss

Complications

Pernicious Anemia (10%)

Carcinoid Tumors

Gastric Cancer

Term

What are the most common causes of Peptic Ulcer Disease?

What are the most common locations?

Definition

H.pylori, NSAIDs, Gastrinoma

Locations: Duodenum, Stomach

Term

How does H.pylori cause duodenal ulcers?

What blood type gets worse more duodenal ulcers?

Definition

Acid production induces gastric metaplasia in duodenum

H.pylori colonizes and causes inflammation

Blood Type: O

Term
How is low grade MALT lymphoma treated
Definition
Antibiotics
Term
What are the causes of Hypertrophic Gastropathy
Definition

Menetrier's(more common in Men)

Gastric hyperplasia of Surface and Pits

Gland atrophy and excessive mucous production

 

Hypertropic-Hypersecretory Gastropathy

Hyperplasia of Parietal and Chief

 

Gastrin induced Hyperplasia

Zollinger Ellison Syndrome

Term
What are the different types of gastric polyps and which is neoplastic
Definition

Fundic Gland: FAP, PPI's

Hyperplastic/Inflammatory

Inflammatory Fibroid

Adenoma(neoplastic)

Term
What are some causes of fundic gland gastric polyps
Definition

Familial Adenomatous Polyposis

PPI's: Fundic Polyps particularly

Term
What are some diseases associated with gastric neuroendocrine tumors
Definition

MEN1

Autoimmune Gastritis

Term
What location for gastric carcinoma has been increasing in incidence
Definition
Carcinoma of the Cardia and GE junction
Term

What are the major genes involve in stomach adenocarcinoma?

What are the lauren's classifications for Gastric Adenocarcinomas?

What is the most important criterea for staging a stomach adenocarcinoma?

Definition

Genes

P53

APC

DCC

Lauren's

Intestinal: glandular

Diffuse: Signet ring cells with excessive mucous, "Linitus plastica" Increased wall thickness

Staging: invasion past muscularis mucosa

Term
What are the major genes involved in adenocarcinoma of the stomach
Definition

DCC

APC

P53

Term
What is Krukenberg's Syndrome?
Definition
Signet ring gastic carcinoma infiltrating the ovaries by lymphatic spread
Term
What can be used to better visualize signet ring adenocarcinoma off the stomach
Definition
PAS or Alcian Blue Stain
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