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GI/GU
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124
Nursing
Undergraduate 1
11/09/2011

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Term
Parts of Stomach
Definition
Upper left abdomen
Muscular pouch
Fundus, body, antrum
Cardiac and pyloric sphincters
Rugae
3 layers
Term
About the stomach
Definition
Secretes digestive enzymes, water, hydrochloric acid, intrinsic factor
2-2.5 liters of gastric secretions daily
Gastric mucosa covered by thick mucous gel layer
Impermeable to hydrogen ions
Mucosal cells also secrete bicarbonate
Parasympathetic and sympathetic nerves
Term
about Gallbladder and bile ducts
Definition
Pear-shaped organ – lower surface of liver
Can hold 50mL
Stores and concentrates bile
Bile moves to hepatic ducts to common bile duct to pancreatic duct to duodenum (sphincter of Oddi)
Gall bladder not essential for life
Bile helps break down and absorb fats
600 to800 mL produced daily
Term
About the Pancreas
Definition
Pancreas
Posterior abdomen, near duodenum and spleen
Exocrine and endocrine (insulin) functions
Groups of secretory cells (acini) make digestive enzymes
Enzymes pass through ducts to ampulla of Vater at sphincter of Oddi
2L enzymes made per day
Trypsin
Pancreatic amylase
Term
about the Small intestine
Definition
1 inch wide
20 feet long
Duodenum, jejunum, ileum
Term
about the large intestine:
Definition
Large intestine
2.5 inches wide
5 feet long
Cecum, colon, rectum
Term
More about the Small intestine
Definition
 Digestion of food and absorption of nutrients
 Mucus-secreting glands protect from stomach acid and
pancreatic enzymes
 Intestinal mucosa will not absorb large molecules – need to be
further broken down (pancreatic enzymes)
 Villi – absorption
 90% absorption in small intestine
 Peristalsis – churns and moves chyme
 3-10 hours from stomach to colon
 Parasympathetic increases peristalsis
Term
LES
Definition
lower esophagial sphincter
Term
GERD
Definition
Heartburn
Term
Achlorhydria
Definition
the production of gastric acid in the stomach is absent
Term
Kidneys
Definition
Pair of bean shaped brownish-red structures located retroperitoneally on the posterior wall of the abdomen from the 12th thoracic vertebra to the 3rd lumbar vertebra
Term
ADRENAL GLAND lies on top of
Definition
each kidney-They are independent of each other in function, blood supply and intervention.
Term
Each ureter has 3 narrow areas
Definition
Ureteropelvic junction
Sacroiliac junction
Ureterovesical junction
The ureteropelvic area is most dangerous due to location to the kidney.
Term
Bladder
Definition
Muscular hollow sac just behind the pubic bone
Term
the capacity of the adult bladder is
Definition
400-500ml.
Term
Central hollow area the, vessicle has __inlets, and __ outlet(s)
Definition
2, the ureters
1, urethra
Term
The bladder wall has 4 layers:
Definition
Adventitia: Outermost layer-connective tissue
Detrusor Muscle: Smooth muscle
Submucosal layer: loose connective tissue
Inner most Mucosal layer: The inner layer contains special transitional cell epithelium- a membrane that is impermeable to water and prevents reabsorption of urine stored in the bladder.
Term
micturition
Definition
voiding, peeing, weeing, pissing,
Term
BPH
Definition
Benign prostatic hypertrophy
Term
Urine is formed in the nephron through a complex 3 step process
Definition
Glomerular filtration
Tubular reabsorption
Tubular secretion
Term
______& _____are usually filtered at the level of the glomerulus and reabsorbed so the NEITHER is excreted in the urine
Definition
Amino Acids and Glucose
Term
RENAL GLYCOSURIA: occurs if
Definition
the amount of glucose in the blood and glomerular filtrate exceeds the amount that the tubules are able to reabsorb.
Term
Blood flows through the kidney AT
Definition
1200 ml/min-
Term
Filtration occurs as blood enters the
Definition
glomerulus from the afferent arterole
Term
Normally there is about ___L per day of filtrate-(99% is reabsorbed in the resulting in1-2L of urine daily)
Definition
180
Term
Efficient filtration depends on:
Definition
adequate blood flow that maintains a consistent pressure through the glomerulus.
Term
Both the 2nd and 3rd steps of urine formation occur in the
Definition
renal tubules.
Term
In tubular reabsorption substances move from the filtrate back into
Definition
the peritubular capillaries or the vasa recta.
Term
In tubular secretion; substances move from peritubular capillaries or the vasa recta into the
Definition
tubular filtrate
Term
Osmolarity: refers to
Definition
the ratio of solute to water
Term
Osmolality:
Definition
number of osmoles dissolved per kilogram of solution
Term
Sodium regulation is controlled by
Definition
aldosterone- it fosters(renal) reabsorption of sodium
Term
Release of Aldosterone is largely under control of
Definition
Angiotensin II
Term
Vasa Recta vessels of the kidney
Definition
constantly monitor blood pressure as blood begins its passage into the kidneys-
Term
When Vasa recta recognize an increase in BP, _____ secretion stops…
Definition
RENIN
Term
is the primary test of renal clearance
Definition
A 24 hour urine collection
Term
Creatinine is
Definition
an endogenous waste product of skeletal muscle that is filtered at the glomerulus, passed through the tubules with minimal change and excreted in the urine.
Term
Creatinince Clearance is a good measure of
Definition
the glomerular filtration rate (GFR)
Term
Factors affecting renal clearance:
Definition
1. how quickly the substance is filtered across the glomerulus
2. how much of the substance is reabsorbed along the tubules
3. how much of the substance is secreted into the tubules
Term
The GFR can vary normal =
Definition
125 ml/min
Term
Creatinine Clearance is an excellent measure of
Definition
renal function
as renal function declines creatinine clearance decreases
Term
Glomerular filtration rate (GFR)
Definition
describes the flow rate of filtered fluid through the kidney
Term
Creatinine clearance rate (CCr or CrCl) is
Definition
the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR.
Term
Creatinine
Definition
is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass).
Term
When the kidneys detect a decrease in oxygen in renal blood flow they release
Definition
erythopoietin
Term
erythopoietin
Definition
is a glycoprotein hormone that controls erythropoiesis, or red blood cell production.
Term
Kidneys are responsible for the final conversison of inactive Vit D to its active form-Vit D is necessary for mantaining
Definition
normal calcium balance
Term
The major waste product of protein metabolism is
Definition
UREA, 25-30 gms are produced and excreted daily
Term
Other waste products that must be excreted are:
Definition
Creatinine
Phosphates
sulfates
Term
Initiation of voiding occurs when
Definition
the efferent pelvic nerve stimulates the bladder to contract-
Term
Causes of Urinary Dysfunction
Definition
Increase in urine volume
Decreased bladder capacity
Inflammation with increased sensitivity of urinary tract
Pressure from abdominal masses
Incomplete bladder emptying
Anxiety
Term
Dysuria
Definition
Painful or difficult urination, usually accompanied by frequency and urgency
Suggests inflammation or irritation of lower urinary tract
When discomfort occurs is important:
-beginning- problem with urethra
-during or after- problem in
Term
Nocturia
Definition
May suggest decreased function in the renal paranchyma
Often occurs when no disease is present
Term
Causes of Nocturia
Definition
Large amount of fluid in evening
Diuretic effect of coffee and alcohol
Medication induced
Elderly with generalized fluid retention during day will have nocturia caused by movement of fluid at rest
Should be investigated if occurs more than twice per night
Term
Nocturnal Enuresis
Definition
Involuntary release of urine during sleep, Bedwetting
In adult: highly suggestive of neurologic disorder
Term
Nocturia/Ped
Definition
Primary: children who have never been dry at night for prolonged periods
Secondary: a child who starts bedwetting when previously dry
Daytime control comes before nighttime
Girls mature before boys
Term
Urinary Retention
Definition
Inability to effectively empty the bladder
Acute: happens frequently post-op, S/P SVD, medication induced or result of lower back or pelvis injury
Chronic: obstruction to urinary tract, neurologic or psychologic disorders
Most pt’s who experience this are completely unable to void
Retention is also considered present if more than 50 cc PVR
Term
Retention/Assessment
Definition
Assess pattern of urinary elimination
How often, amount, frequency, urgency, fullness?
Discomfort above the symphysis?
Palpate the bladder
I & O for the past 24 hours
Bladder scan post void or straight cath
Term
PVR
Definition
post void residual
Term
SVD
Definition
spontaneous vaginal delivery
Term
U Retention/Nursing Dx
Definition
Urinary retention r/t post-op complications

-assess pt
-I & O should be equal within 48
hours of surgery
-Teach pt to void when urgency is
felt
-Provide privacy, warm water, run
water, void q 2-3 hours
Term
Incontinence
Definition
Symptom not a disease
Involuntary loss of urine
Social and health problem
Can be urologic or neurologic related
Aging and childbearing are two factors
Causes stress and embarrassment, people often avoid seeking care
Term
Types of Incontinence
Definition
Total
Reflex
Urge
Stress
Functional
Term
Reflex incontinence is
Definition
caused by a problem in the central nervous system
Term
Prolapse literally means
Definition
"to fall out of place"
Term
Reflex incontinence
Treatment
Definition
First-line: intermittent catheterization
Second-line: indwelling catheterization
Third-line: suprapubic catheterization
Term
Urge Incontinence/definition
Definition
overactive bladder
Results when the feeling to urinate is so strong and so severe that uncontrolled bladder emptying occurs
May be caused by bladder inflammation, tumor or infection
Sometimes due to uninhibited bladder contraction r/t neurologic disorders, such as spinal cord injury
Usually results from idiopathic inability to suppress bladder contractions
Term
Urge incontinence
Definition
Results when the feeling to urinate is so strong and so severe that uncontrolled bladder emptying occurs
May be caused by bladder inflammation, tumor or infection
Sometimes due to uninhibited bladder contraction r/t neurologic disorders, such as spinal cord injury
Usually results from idiopathic inability to suppress bladder contractions
Term
Urge incontinence/Treatment
Definition
First-line: behavioral therapies such as bladder training and bladder drill
Second-line: meds such as oxybutynin (Ditropan), or imipramine (Tofranil)
Term
Stress incontinence
Definition
Unexpected loss of small amounts of urine with rapid increase of intra-abdominal pressure ie coughing, laughing, sneezing, straining or physical activity
Most cases: the pelvic muscles supporting have weakened and normal anatomic position of bladder and urethra has changed
Most common in women
Term
Treatments for Stress Incontinence
Definition
First-line: behavioral therapies such as Kegel’s exercise and bladder training
Second-line: meds such as alpha-adrenergics (prazosin, doxasosin) These drugs help the bladder to retain urine by constricting the sphincter muscle and relaxing the bladder wall. These actions reduce urine leakage due to abrupt increases in pressure on the bladder.
3rd: surgery
Term
Functional incontinence
Definition
Involuntary, unpredictable passage of urine
Cannot control micturition b/c of environmental barriers, physical limitations, or disorientation. Not able to reach in time
Intact lower urinary tract but factors such as immobility, severe cognitive impairment, etc.
Term
Functional incontinence/Nursing Process
Assessment
Definition
Voiding history
Time, place, amt. of urine
Awareness of passage of urine
What stimulates voiding
Past history of urologic, neurologic disease including dementia
Past med/surg, OB history
Hesitancy, urgency, polyuria, dysuria, nocturia
Term
Nursing Dx
Definition
Total incontinence r/t independent contraction of detrusor reflex r/t trauma or surgery
-bladder regimen
-skin is intact
-decreased episodes of
incontinence
-pt. manage bladder elimination
-pt. shows feelings of self-worth
Term
Nosocomial:
Definition
Originating or taking place in a hospital, acquired in a hospital
Term
Ureteral Pain
Definition
Colicky and one of the most severe types of pain known
Caused by sudden obstruction such as calculus, which produces hyperperistalsis and spasm of ureter
Stone produces similar symptoms of renal pain but may radiate to testes or labia
In lower ureter may cause suprapubic pain, bladder, penis or urethra
Term
Renal colic
Definition
is a type of abdominal pain commonly caused by kidney stones.
Term
Cloudy urine
Definition
may indicate UTI
Term
Turbidity:
Definition
refers to clarity of urine. It should be clear
Term
Fruity URINE:
Definition
presence of ketone bodies
Term
Hematuria/Mid age to elderly
Definition
cancer! Although can be infection, calculi, BPH, vascular malformation of kidney, meds
Term
Hematuria/characteristics
Definition
Hematuria at beginning stream -> bleeding of anterior urethra
End of stream -> posterior urethra, bladder neck
Total hematuria -> bleeding within or above bladder
Painful: associated with infections or stones
Painless: more ominous, associated with urinary tract neoplasm
May occur in renal causes: glomerulonephritis
Term
Anuria:
Definition
<100 ml/24 hour period
Term
Oliguria:
Definition
is the low output of urine between 100-400 ml/24
hours
Term
Polyuria:
Definition
excessive excretion of urine
>2500 ml/24 hour period
Term
Anuria & oliguria/causes
Definition
ARF, fluid & electrolyte imbalances, bilateral ureteral obstruction, urethral obstruction
Term
Polyuria/causes
Definition
decrease concentrating of kidneys, increase fluid intake, diabetes insipidus, diabetes mellitus, diuretics
Term
Cystitis
Definition
Inflammation of bladder -> usually results from invasion of bacteria in bladder
Women: bacteria originate from rectum or vagina and ascend upward via urethra, anatomy related
Men: results from another in urinary tract, ie. Prostatitis or BPH
Women > men Can follow medical procedures in urinary tract or incomplete bladder emptying
Also can be associated with sexual intercourse and pregnancy
Occasionally develops when bacteria travel to bladder via vascular or lymphatic systems
Term
Cystitis is
Definition
a term that refers to urinary bladder inflammation that results from any one of a number of distinct syndromes.[1] It is most commonly caused by a bacterial infection in which case it is referred to as a urinary tract infection.[
Term
cystitis/ss
Definition
Dysuria, frequency, urgency, nocturia, nocturnal enuresis, incontinence, urethral pain, low back pain, suprapubic pain and fever
May also complain of tenesmus (episodes of painful straining that are ineffective in producing urine)
Hematuria and urine with strong odor may be present
Term
cystitis/Tx
Definition
Antibiotics: Amoxicillin, Bactrim (Septra, Sulfamethoprim), Cipro, Cephalosporins
For uncomplicated: 3 day therapy
Men and Peds: 7-10 days
Analgesics, urinary antiseptics, anticholinergics for bladder
Term
cystitis/prevention
Definition
Drink 2-3 liters of fluid per day
Notify health care provider of symptoms
Empty bladder when urge is felt
Clean perineum from front to back
Avoid bubble baths and scented T.P.
Wear cotton underwear
Finish prescriptions
Repeat urine culture
Empty bladder following intercourse
Term
Urethritis
Definition
Inflammation of urethra
Presents with similar s/s to cystitis
May be acute or chronic
Occurs in men and women
Most common cause: STD’s Gonorrhea, chlamydia, trichomonas
Can also be caused by irritants such as soaps, perfumed T.P., sanitary napkins
Term
Urethritis/ss
Definition
Burning, frequency, nocturia, difficulty with urination
Men: usually have discharge from urethral meatus Women: don’t
Both sexes c/o lower abdominal discomfort
Term
Ureteral Stricture
Definition
Abnormal narrowing or ureter, can occur at any point however 3 areas most prone:
-uteropelvic junction
-midureter
-just above uterovesical junction
Term
Urethral Stricture
Definition
Pathologic narrowing of urethra
More common in men than women
Can be congenital or acquired
Acquired: chronic infection, STD’s or trauma women: intercourse, childbirth, vaginal surgery or chronic urethritis
Also: instrumentation, longterm use of indwelling catheters, neoplasms, venereal warts, and polyps
Term
Urethral Stricture/ss
Definition
Most common: decreased force of urinary stream
Hesitancy
Double voiding, post void dribbling
Interrupted urinary stream
Urinary retention
Overflow incontinence
Dysuria, frequency, nocturia, urgency and urge incontinence
Term
Urethral Stricture/Tx
Definition
Goal: relieve obstruction and eradicate existing infection
Mechanical dilation is often used: local anesthetic and curved metal rods (sounds) to gradually open up stricture
Internal urethrotomy: incises strictured area. Requires intermittent self-cath to keep open
Term
Bladder trauma/ss
Definition
Gross hematuria, lower suprapubic or abd pain
Rectal exam may reveal pelvic hematoma
In multiple trauma not a priority
Term
Bladder Cancer/about
Definition
Malignant tumors are most common tumors in urinary system (unless prostate is included, then prostate is)
50,000 new cases diagnosed each year
5 year survival rates are just as good for superficial tumors
5 year survival rate for extensive tumor growth 10-50%
Term
Bladder Cancer/Dx
Definition
Symptoms, history, and diagnostic tests
Want to stage tumor to ascertain treatment
Urine for cytology, excretory urography or CT, cystoscopy to biopsy lesion
Term
Cutaneous Ureterostomy:
Definition
reroutes the ureters to the surface of the abdomen forming a small stoma: risk of infection high
Term
Ileal Conduit:
Definition
most common type- small piece of ileum is removed with blood and nerve supply intact- the remainder of the ileum is reconnected so the bowel flow is not disrupted-the free segment of the ileum is sutured closed and the other end is brought out to the abdominal wall and a stoma is created.
Term
Continent Urostomy: also called an ileal bladder conduit- or Kock pouch
Definition
It is a variation of the ileal conduit- Urine drain from the ureters into a surgically created ileal pouch. The stoma created on the abdomen contains a nipple valve to keep urine from leaking. The patient inserts a catheter to drain the urine through the valve. A second valve prevents reflux of urine back into the kidneys.
Term
24 hour Urine Collection
Definition
Have patient void and record the time
Discard the first void
Save all the urine for the next 24 hours
Inform the patient
Post signs for other staff to collect the urine
Container usually is supplied by the lab
Term
specific gravity value normal
Definition
1.002-1.030
Term
Crede Manuever
Definition
Application of manual pressure over lower abdomen to promote emptying of bladder.
Term
Esophagus/about
Definition
Begins at lower level of pharynx
Hollow muscular tube – 10 inches (25 cm)
Smooth and skeletal muscle
Sphincter at both ends
Term
Achlorhydria or hypochlorhydria:
Definition
refers to states where the production of gastric acid in the stomach is absent or low, respectively.
Term
Borborygmus
Definition
also known as stomach growling, rumbling
Term
Dysphagia is
Definition
the medical term for the symptom of difficulty in swallowing.
Term
Eructation
Definition
Belching
Term
Gastric lavage
Definition
commonly called stomach pumping
Term
gastritis
Definition
the lining of the stomach becomes inflamed or swollen
Term
Gastroenteritis
Definition
also known as gastric flu, stomach flu, and stomach virus, although unrelated to influenza
Term
Hematemesis or haematemesis is
Definition
the vomiting of blood.
Term
Fecal occult blood (FOB)
Definition
refers to blood in the feces that is not visibly apparent. A fecal occult blood test (FOBT) checks for hidden (occult) blood in the stool
Term
Odynophagia
Definition
is painful swallowing
Term
Percutaneous endoscopic gastrostomy (PEG) is
Definition
an endoscopic medical procedure in which a tube is passed into a patient's stomach through the abdominal wall, most commonly to provide a means of feeding when oral intake is not adequate.
Term
Stoma
Definition
is an opening (a direct translation of the Koine Greek would be "mouth"), either natural or surgically created, which connects a portion of the body cavity to the outside environment.
Term
Peritoneum
Definition
the serous membrane that forms the lining of the abdominal cavity
Term
GI Changes in the older adult/mouth
Definition
Mouth – teeth darken, may fracture, gums recede
Saliva decreases
Taste lessens
Term
GI Changes in the older adult/below mouth
Definition
Decreased motility
LES less competent - GERD
Achlorhydria
Gall stones increase
Impaired absorption
Chronic constipation
Term
Gastroparesis
Definition
is a medical condition consisting of a paresis (partial paralysis) of the stomach, resulting in food remaining in the stomach for a longer period of time than normal.
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