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GI - Esophageal Disorders
PA CLin Med
43
Health Care
Graduate
01/12/2010

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Cards

Term
2 distinct areas that may caus dysphagia:
Definition
1. oropharyngeal
2. esophageal
Term
which type of disorders cause dysphagia of liquids/solids?
Definition
1. motility disorders: liquids and solids
2. Mechanical obstruction: solids
Term
define: odynophagia
Definition
pain on swallowing
Term
4 etiologies of odynophagia:
Definition
1. caustic ingestion/reflux
2. pill-induced esophagitis
3. infection
4. obstructing tumor
Term
sour tasting regurge indicates:
Definition
it is from the stomach w gastric acid mixed in
Term
bitter tasting regurge indicates:
Definition
it is from the duodenum; bile
Term
define water brash:
Definition
outpouring of saliva in response to GERD
Term
most common of all esophageal sx:
Definition
heartburn
Term

aggravating factors of pyrosis:8

Pneumonic: FC SPICES

Definition

1.Fat

2. Caffine

3. Spicy

4. Position (lying flat)

5. Intoxicant (alc)

6. Chocolate

7. Emotions

8. Smoking

Term
how does reflux differ from angina:4
Definition
1. pain during sleep - not so in angina
2. lasts hours to days
3. hot/cold food/liquids aggrevate
4. releived with antacid
Term
elderly, alcohol, hiatal hernia, abn esophageal motility are all risk factors for:
Definition
pill induced esophagitis
Term
4 drugs infamous for pill induced esophagitis:
Definition
1. Foxamex
2. doxycycline
3. Vit C
4. NSAIDs
Term
Esophageal varicies are caused by:
Definition
Portal HTN from alcoholic and viral liver cirrhosis
Term
where do the varicies occur in the esophagus?
Definition
lower 1/3, gastroesophageal junction, bleeding is most common in the distal 5cm of esophagus
Term
prognosis of esophageal varicies:
Definition
1. bleeds in 1/3 of cases
2. 50% of bleeds stop spontaneously
3. of the bleeds 20% mortality wn 6wks
Term
tx/management of esophageal varicies:
Definition
1. Betal blockers
2. endoscopic variceal ligation
Term
describe Mallory-Weiss Syndrome:
Definition
mucosal laceration of the gastroesophageal junction from portal HTN & 50% have hx of vomiting/retching
Term
dx of Mallory-Weiss syndrome:
Definition
Endoscopy shows eliptical or longitudinal ulcer
Term
tx of Mallory-Weiss:
Definition
1. fluids
2. xfuse if indicated
3. hemostatisis; epi injetion or cautery
Term
describe Barret's Esophagus:
Definition
constant reflux causes change of squamous to collumnar epi, can evolve to cancer
Term
epidemiology of barret's esophagus:
Definition
1. 10-20% of GERD patients
2. Males 3:1
3. avg pt = 55yo white male
Term
dx of barrets esophagus:
Definition
endoscopy with bx
Term
describe Zenker's Diverticulum:
Definition
protrusion of PHARYNGEAL mucosa @ the esophopharyngeal junction from the loss of elasticity of the UES causing halitosis and regurge
Term
dx of zenkers diverticulum:
Definition
barium esophagram
Term
zenkers diverticulum tx:
Definition
surgery
Term
3 most common motility disorders of the esophagus:
Definition
1. Achalasia (enteric nervous sys)
2. diffuse esophageal spasm
3. scleroderma (smooth m dz)
Term
describe achalasia:
Definition
loss of ganglion cells in the enteric nervous sys of the esophagus leads to impaired relaxation of the LES and absent peristalsis
Term
epidemiology of achalasia:
Definition
peaks in 40's
men 2:1
Term
TQ: "bird Beak stricture"
Definition
Achalasia seen in barium swallow
Term
sx of achalasia:
Definition
1. dysphagia
2. non-acidic regurge
Term
dx of achalasia:
Definition
1. barium swallow (bird beak)
2. x-ray
3. manometry
Term
manometry findings in achalasia:
Definition
1. high resting LES pressure
2. incomplete or abn relaxation of LES upon swallow
3. incomplete/abn peristalsis
Term
2 pharmacotherapies for achalasia:
Definition
1. nitrates
2. calcium channel blockers
both are poorly tolerated or ineffective
Term
tx for achalasia:4
Definition
1. pharmacotherapy
2. mechanical dilation excellent short term need to repeat in 5yrs
3. surgical myotomy; remission @85% @10yrs but develop GERD post-op
4. Botulinum toxin injection
Term
uncommon motor disorder assoc w degeneration of Auerbach's plexus
Definition
esophageal spasms
Term
sx of diffuse esophageal spasm:
Definition
1. substernal CP
2. Dysphagia w pain
Term
manometry findings in diffues esophageal spasm:
Definition
normal pressure unless it is done during the spasm episode
Term
barium x-ray appearance of esophageal spasm:
Definition
corkscrew esophagus
Term
Tx of esophageal spasm:
Definition
1. trial of sm m relaxants
2. trial of antidepressants
3. relaxation exercises, therapy
Term
3 indications for upper endoscopy:
Definition
1. eval for reflux-induced esophageal injury
2. Sx not responding to tx
3. sx are chronic &/or refractory to tx
Term
what is the first test used in dx dysphagia:
Definition
barium swallow
Term
which two suspected disorders indicate manometry:
Definition
achalasia & esophageal spasm
Term
5 categories of esophageal disorders:
Definition
1. dysphagia
2. heartburn
3. odynophagia
4. hematemesis
5. noncardiac CP
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