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GI Drugs
IOS 7 Exam 1 Drugs
11
Pharmacology
Professional
02/07/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
Ranitidine
Definition

H2 Antagonist, Decreases Gastric Acid Secretion

 

SE's: headache, nausea, dizziness, gynecomastia (men), galactorrhea (women), CNS effects esp. in the elderly (delirium, confusion, slurred speech)

Term
Nizatidine
Definition

H2 Antagonist, Decreases Gastric Acid Secretion

 

SE's: headache, nausea, dizziness, gynecomastia (men), galactorrhea (women), CNS effects esp. in the elderly (delirium, confusion, slurred speech)

Term
Famotidine
Definition

H2 Antagonist, Decreases Gastric Acid Secretion

 

SE's: headache, nausea, dizziness, gynecomastia (men), galactorrhea (women), CNS effects esp. in the elderly (delirium, confusion, slurred speech)

Term
Cimetidine
Definition
headache, nausea, dizziness, gynecomastia, galactorrhea, CNS effects esp. in the elderly (delirium, confusion, slurred speech), loss of libido (androgen receptor agonist when used chronically), inhibition of CYP450 (affects warfarin, phenytoin, sulfonylureas, CCBs)
Term
Omeprazole
Definition

Inhibits the H+/K+/ATPase proton pump which is only expressed on the parietal cell (not reversible)

 

sig. increase in gastric pH (affects abs. of dig, nifedipine, griseofulvin, ketoconazole, itraconazole, vit B12, cefpodoxime), altered CYP450 activity (affects diazepam, warfarin, phenytoin), C dif, CAP, hip fracture

Term
Pantoprazole
Definition

Inhibits the H+/K+/ATPase proton pump which is only expressed on the parietal cell (not reversible)

 

sig. increase in gastric pH (affects abs. of dig, nifedipine, griseofulvin, ketoconazole, itraconazole, vit B12, cefpodoxime), altered CYP450 activity (affects diazepam, warfarin, phenytoin), C dif, CAP, hip fracture

Term
Esomeprazole
Definition

Inhibits the H+/K+/ATPase proton pump which is only expressed on the parietal cell (not reversible)

 

sig. increase in gastric pH (affects abs. of dig, nifedipine, griseofulvin, ketoconazole, itraconazole, vit B12, cefpodoxime), altered CYP450 activity (affects diazepam, warfarin, phenytoin), C dif, CAP, hip fracture

Term
rabeprazole
Definition

Inhibits the H+/K+/ATPase proton pump which is only expressed on the parietal cell (not reversible)

 

sig. increase in gastric pH (affects abs. of dig, nifedipine, griseofulvin, ketoconazole, itraconazole, vit B12, cefpodoxime), altered CYP450 activity (affects diazepam, warfarin, phenytoin), C dif, CAP, hip fracture

Term
Lansoprazole
Definition

Inhibits the H+/K+/ATPase proton pump which is only expressed on the parietal cell (not reversible)

 

sig. increase in gastric pH (affects abs. of dig, nifedipine, griseofulvin, ketoconazole, itraconazole, vit B12, cefpodoxime), altered CYP450 activity (affects diazepam, warfarin, phenytoin), C dif, CAP, hip fracture

Term
Misoprostol
Definition

A slowly metabolized analog of PGE1 that inhibits the proton pump and induces mucous secretion


Diarrhea

Term
metoclopramide
Definition

D2 antagonist-blocked by atropine

Enhancement of cholinergic neurons of the parasympathetic nervous system

 

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