Term
|
Definition
Antacid
se- constipation
Calcium antacids taste like chalk. |
|
|
Term
Bulk Laxatives (fiber)
Saline/Osmotic Laxatives (glycerine,sorbitol)
Irritant or Stimulant Laxatives (bisacodyl, phenolphalein, seena, castor oil)
Stool Sofener (docusates) |
|
Definition
|
|
Term
Omeprazole
and other Prazoles |
|
Definition
PPIs
Mech: Permanently disable H/P ATP pump on parietal cells. |
|
|
Term
|
Definition
| prostglandins- mucous layer protecting agent |
|
|
Term
|
Definition
coating agents
mech: fills ulcers; protects from acid |
|
|
Term
| helicobacter pylori treatment |
|
Definition
2 antibiotics (clarithromycin, amoxicillin)
and
1 PPI |
|
|
Term
|
Definition
|
|
Term
1. metoclopramide
2. domperidone |
|
Definition
prokinetic
mech: D2 agonist
action: stim GI motility and anti emetic (central)
SE: tardive dyskinesia + stims prolactin release (leads to gynecomastia)
1. can pass BBB more SE
2. no passage thru BBB, less effective |
|
|
Term
1. tegaserod
2. prucalopride |
|
Definition
prokinetic
approved under restricted use- no heart probs, must sign waiver |
|
|
Term
|
Definition
prokinetic
mech: motilin agonist on muscle and nerves
SE diarrhea
also antibiotic derp derp |
|
|
Term
|
Definition
| post-operative ileus (hospital only) |
|
|
Term
1. methylnaltrexone
2. alvimopan |
|
Definition
μ-opoid antagonist
1. constipation - SE flatulence
2. post op ileus- 7 day use only (mi risk)
only used in hospital
only drug for IBS really |
|
|
Term
|
Definition
opiod w/ no cns activity
DO NOT USE WITH IBD
can cause toxic megacolon |
|
|
Term
1. glucocorticoids ( budesonide)
2. sulfasalazine |
|
Definition
IBD
2. maintains IBD remission
prodrug, cleaved by colonic bacteria
5A-salacylic acid derivative
5(ASA)
tx- folate deficiency, reversible male infertility |
|
|
Term
|
Definition
immunosuppresants for IBD
mech: TNF-α inhibitors |
|
|
Term
|
Definition
5ht3 receptor agonist
female patients with diarrhea predominant IBS |
|
|
Term
ondansetron
tropisetron
granisteron
palosetron |
|
Definition
anti emetics
5-HT3 antagonist (vagal) |
|
|
