Term
| 98% of all CA in the colon/rectum are what type? |
|
Definition
|
|
Term
| peak incidence of colorectal CA |
|
Definition
| 60-79;<10% are before 50yo |
|
|
Term
| colorectal CA has a direct correlation with which food> |
|
Definition
| direct correlation with red meat |
|
|
Term
| 6 risk factor for colorectal CA: |
|
Definition
1. >50yo
2. Red, processed heavily cooked meats
3. smoker/etoh
4. obesity (esp truncal)
5. FHx colorectal CA
6. PMHx CA/IBD |
|
|
Term
| key CC of Colorectal CA:5 |
|
Definition
1. blood in stool
2. abd pain
3. constipation/diarrhea/stool caliper
4. weight loss
5. fatigue |
|
|
Term
| cecal & right colon CA characteristics: |
|
Definition
1. CA can grow wo obstructing bc stool is liquid at this point
2. lesions bleed; chronic blood lost wo change in stool
3. fatigue/palpitations/angina dt anemia
4. occult bld may be neg bc CA may bleed intermittently |
|
|
Term
| transverse/decending colon CA characteristics: |
|
Definition
Tumors may impede passage of stool leading to:
1. Abd cramping
2. occasional obstruction
3. perforation
4. apple core radiograph |
|
|
Term
| which types of polyps are premalignant: |
|
Definition
| adenomas but only <1% develop into CA |
|
|
Term
| 2 types of adenomatous polyps: |
|
Definition
1. pedunculated
2. sessile (flat) |
|
|
Term
| for pts w poolyps, colonoscopy is recommended q __ yrs |
|
Definition
|
|
Term
| hematochezia, tenesmus, pencil-like stools: sx may be mistaken for hemorrhoids |
|
Definition
|
|
Term
| what is the laboratory cancer marker for colorectal cancer? |
|
Definition
| CEA - carcinoembryonic antigen |
|
|
Term
| which labs would most likely be elevated with mets of colorectal CA: |
|
Definition
|
|
Term
| In colorectal CA, CBC would show: |
|
Definition
|
|
Term
|
Definition
| complete resection of malignant tissue and assoc. lymphs |
|
|
Term
| when is pallative colostomy used? |
|
Definition
| unresectable mass w obstruction |
|
|
Term
| radiation therapy is used in conjunction with _______ in Colorectal CA: |
|
Definition
|
|
Term
| lab used to monitor post-op colorectal CA: |
|
Definition
|
|
Term
| most important predictor of patients survival of colorectal CA: |
|
Definition
| stage of dz at time of surgery |
|
|
Term
| 5yr survival for stage A vs stage D Colorectal CA: |
|
Definition
|
|
Term
| Colorectal CA stage: superficial lesion that do not penetrate the muscularis, serosa or involve regional lymph nodes |
|
Definition
|
|
Term
| colorectal CA stage: distant mets involved |
|
Definition
|
|
Term
| colorectal CA stage: more invasive but no spread to regional lymph nodes |
|
Definition
|
|
Term
| colorectal CA stage: regional lymph node involvement: |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| TNM of stage C colorectal CA: |
|
Definition
|
|
Term
|
Definition
|
|
Term
| colorectal ca screenings recommended q5yrs: |
|
Definition
1. OCB (this one is every yr)
2. flexible sigmoidoscopy
3. barium enema |
|
|
Term
| colorectal screening method that is recommended every 10 years: |
|
Definition
|
|
Term
| recommendations for those with FHx of colorectal ca: |
|
Definition
1. first deg reletaive dx >60, begin screeings at 40yo
2. first degree relative dx<60yo or multiple first deg relatives = begin screenings at 40 or at 10yrs younger than FHx Dx; colonoscopy Q5Y |
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