Term
| principles of drug action |
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Definition
- absorption
- distribution
- metabolism
- excretion
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Term
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Definition
| how the drug works in the body physiologically and biochemically |
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Term
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Definition
| process by which a drug moves through the body and eventually is eliminated |
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Term
| effect and effectiveness of a drug depends on... |
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Definition
| absorption: process by which medications enter the blood stream |
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Term
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Definition
- route of administration
- drug solubility (sustained - release)
- site of administration
- acid base environment of body fluids
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Term
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Definition
- delivery to target cells
- effectiveness depends on the concentration of the medication at the reactive site. (ex - fat cells and insulin): some medications are bound to plasma proteins and decrease the amount available, depends on circulation, some medications have affinity for certain tissue --> iodine
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Term
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Definition
- drugs must be deactivated for excretion
- this is biotransformation or metabolism
- takes place mainly in the liver, but also occurs in kidneys, blood, intestinal mucosa and lungs
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Term
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Definition
- the desired and intended effects of the medications vary with
- nature of meds
- length of time taking the meds
- clients physical condition
- interactions with other meds
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Term
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Definition
- effects other than primary therapeutic effects
- some side effects are essentially harmless
- others are potentially harmful - ex: stop antibiotic if get rash
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Term
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Definition
- secondary effect of medication
- toxicity
- cumulative effects
- individual client sensitivity: allergic reaction
- idiosyncratic reactions
- drug interactions
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Term
| factors affecting drug action |
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Definition
- age
- weight and height
- gender
- genetic factors
- time of administration
- organ system function
- psychological state
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Term
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Definition
- medication history
- allergies
- medical history
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Term
| before medication administration, assess.. |
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Definition
- medical record
- diet and fluid orders
- laboratory values
- physical assessment - swallowing, GI motility, muscle mass, vital signs, body system assessment
- knowledge and compliance
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Term
| administering medications using the 5 Rights |
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Definition
- right client
- right medication
- right dose
- right time
- right route
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Term
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Definition
- immediately after medication is given
- include time, route, dosage, and site of administration
- nurse's initial and signature
- special documentation if medication is not given
- heparin and insulin have separate flow sheets
- document therapeutic and side effects
- if a medication error, fill out an incident report
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Term
| routes of administration - orally |
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Definition
- simples and easiest
- decreased patient discomfort
- decreased side effects and less expensive
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Term
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Definition
- pill
- liquid
- patch
- suppository
- subcutaneous
- cream
- inhaler
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Term
| systems of medication distribution |
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Definition
- stock supply
- unit dose
- self administered supply: PCA and home care
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Term
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Definition
- chemical name
- generic name
- classification
- action of drug
- indication: why taking
- side effects
- nurse interventions: assessments while on meds, patient education
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