Term
| Brand name for famotidine |
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Definition
| Pepcid AC, Pepcid AC max strength |
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Term
| Brand name for ranitidine |
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Definition
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Term
| Brand name for Nizatidine |
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Definition
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Term
| duration of action of H2 Blockers |
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Definition
Longer duration of action than antacids, but shorter than PPIs. |
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Term
| When can H2 blockers be used? |
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Definition
Can use prn, or at bedtime for night-time heartburn symptoms |
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Term
| Should H2 blockers be given with PPIs? |
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Definition
Occaionally may be appropriate with PPI if H2-Blocker used at bedtime for night-time reflux Sx - otherwise, do not use H2-blockers with PPIs. |
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Term
| Reanl concerns with H2-Blockers |
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Definition
Use lower doses in elderly and knwon renal disease to avoid excessive CNS effects. |
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Term
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Definition
| Statement. Not a question. |
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Term
| Significant H2-Blocker drug interactions |
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Definition
(1) CNS: Additive side effects, if elderly or reduced renal function - use lower doses.
(2) Caution with concurrent use of itraconazole, ketoconazole, calcium carbonate and iron, due to reduced absorption from increased pH
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Term
| Significant H2-Blocker drug interactions concerning Cimetidine |
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Definition
3A4 Inhibitor and weak - moderate inhibitor of other isoenzymes
Do not use with mesalamine, thioridazine, and caution (due to levels) of many other drugs, including amiodarone, phenytoin, carbamazepine, theophylline, among others.
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