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Details

GERD Other Agents
GERD Other Agents
16
Pharmacology
Professional
08/28/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
MOA for misoptrostol
Definition

Prostaglandin E1 analog: replaces gut - protective PG removed by NSAIDs

Term
Sulcralfate MOA?
Definition

forms a complex by binding with positivley charged proteins that protect the stomach lining against pepsin and HCL

Term
Name the cytoprotective agents
Definition
Misoprostol & Sucralfate
Term
Brand name for misoprostol
Definition
Cytotec
Term
What pregnancy category is misoprostol?
Definition
pregnancy category X
Term
should misoprostol be used on women of child bearing age?
Definition

Do not use in women of childbearing age unless strict compliance with contraceptive measures

Term
starting dose for misoprostol
Definition

Can start with 100 mcg right after dinner (with food in stomach), attempt to increase as-directed. Use of psyllium (Metamucil) may help decrease diarrhea

Term
Major side effect of sucralfate?
Definition

major side effect is constipation; drink adequate fluids and use laxitives if directed.

Term
[image]
Definition
Statement. Not a question.
Term
MOA of metoclopramide
Definition

Dopamine antagonist. At higher doses, blocks 5HT receptors in chemoreceptor zone, enhances response to acetylocholine causing enhanced motility and accelerated gastric emptying (peristatic speed)

Term
brand name for Metoclopramide
Definition
Reglan
Term
Dosing for metoclopramide
Definition

10 mg QID 30 min before meals and at bedtime

Term
Other concerns regarding metoclopramide
Definition

Serious ADRs due to DA - blockade

 

Extrapyramidal symptoms (EPS), including Parkinsonism (Parkinson disease - like symptoms)

Term
[image]
Definition
Statment. Not a question.
Term
Should metoclopramide be used in those receiving meds for parkinson disease?
Definition

No. Do not use in patient receiving medication for Parkinson disease (counter - effect)

 

Term
Should alcohol be avoided whilst on this drug?
Definition

Avoid consuming alcohol during treatment with this drug. Alcohol may increase drowsiness and dizziness.

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