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Genetics
GRE Genetics Section
21
Biology
Graduate
03/28/2011

Additional Biology Flashcards

 


 

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Term
Autosomal Recessive
Definition

Traits skip generations

Traits can appear in siblings without appearing in parents

 

Term
X-Linked Dominant
Definition

All daughters of male who has the trait will also have the trait

 

No male to male transmission

 

Female with the trait only passes it on to her child if the child gets the infected X

Term
X-Linked Recessive
Definition

Trait is far more common in females than males

 

all daughters of male with the trait will have atleast one copy of the trait

 

No male-to-mail transmission

 

If male has the trait, mother must have atleast 1 copy

Term
Males cannot be carriers of what traits
Definition
Sex-linked (X-linked)
Term
Are dominant alleles more frequent than recessive alleles?
Definition
No
Term
Codominance
Definition

Different alleles for a trait each code for enough proten than when they occur together, two different normal proteins are made

 

Ex. Blood type IA, IB, i

 

Both phenotypes show up fully

Term
Incomple Dominance
Definition

Dominant allele does not code for enough of a given protein, so you see only the full effect when 2 copies of the dominant allele are present in the cell

 

ex...RW=Pink flowers

Term
Epistasis
Definition

Second gene determines whether a first gene is expressed or not

 

Ex: B = black b = brown, C = color c= no color

 

Term
Mitochondrial/maternal inheritance
Definition

Cellular organelles derive entirely from mother (sperm contain no organelles that are transferred to the egg upon fertilazation)

 

Genes in organnelles have maternal DNA

Term

Genomic Imprinting

 

Epigenesis

Definition

Certain genes seem to be encoded differently depending on which parent it comes from

 

methylation?

 

Ex. Mom's recessive allele causes disease but same one from dad doesnt!

 

Identical Genotypes = Different phenotypes

Term
Triplet Repeat Extension
Definition

Some genes contain terminal regions of nucleotide repeats CAG


Excess repeats =

 

Huntings

 

Fragile X

Term
Genetic Anticipation
Definition

Seen in repeat expansion diseases

 

Building up of a traight over the course of several generations

Term
Nucleosome
Definition

DNA wrapped around a histone

 

Term
snRNP
Definition

small nuclear ribonucleoprotein

 

stabalizes RNA in the nucleus

 

splicosome

Term
Transposon
Definition

transposable genetic elements

 

pieces of DNA that can move from place to place within an organism's genome

 

in bacteria: chromosome < --> plasmids

 

transp;osase enzyme and inverted repeats

 

Ab Resistance genes

Term
introns
Definition

only in eukaryotic genes

 

spliced out

Term
enhancer
Definition

non-coding region of dna that influences the activation of other genes

 

Bring transcription factors into contact with promoter regions of genes to enhance transcription

Term
TATA boxes
Definition

In promoter regions

 

A-T rich regions of DNA that are involved in the start of transcription

 

regions of dna rich in adenine and thymine tend to separate more easily than those rich in Cs and Gs

 

A/T form 2 double bonds, not 3

Term
promoters
Definition
RNA polymerase must bind to promoter sequence to begin transcription of structural genes
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