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Genetics
Chapter 6 & 7
23
Science
Undergraduate 2
03/13/2008

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Cards

Term
RecA
Definition

binds 3' tail and double helix allowing invasion and migration

 

Term
Chargaff's Rule
Definition

A forms hydrogen bonds with T

C forms hydrogen bonds with G 

Term
Origin of Replication
Definition
Where the unwinding begins
Term

DNA Polymerase III

 

Definition
adds nucleotides to the growing strand
Term
Polymerization
Definition
Formation of the phosphodiester bonds
Term
Leading Strand
Definition
adds nucleotids 3'-5'
Term
Lagging Strand
Definition
adds nucleotides 5'-3'
Term
okazaki fragments
Definition
Fragments of the lagging strand
Term
primase
Definition
creates RNA primers to initiate synthesis
Term
Ligase
Definition
Welds together okazaki fragments
Term
Topoisomerase
Definition
Enzyme that relaxes supercoils by nicking strands
Term
Recombination
Definition
Results in genetic exchange of nucleotides between homologous chromosomes resulting in new combinations of alleles
Term
Forward Mutation
Definition
changes wild-type to mutated type
Term
Reverse Mutation
Definition
From mutated-type back to wild-type
Term
Substitution Mutation
Definition
Base is replaced by one of the other three bases
Term
Insertion Mutation
Definition
block of one or more DNA pairs is added
Term
Deletion Mutation
Definition
Block of one or more DNA pairs is deleted
Term
Inversion
Definition
180 rotation of piece of DNA
Term
Translocation Mutation
Definition
Parts of nonhomologous chromosomes change places
Term
Excision Repair
Definition
cuts out damaged part of DNA bases and some surrounding bases and fills in the gaps by copying the remaining DNA strand to replace the damaged DNA
Term
Methyl-directed
Definition
Recognizes mismatched base pairs during replication and correctly replaces them using the methylated parent strand as a references
Term
Complementation Group
Definition
A collection of mutations that ar ein the same gene
Term
Polymerase I
Definition
Replaces RNA primers in DNA
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