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Definition
| characteristic expressed in one sex and not the other even if both sexes have the genotype |
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| characteristic expressed more frequently in one sex over the other |
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| chemical that simulates radiation |
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| restriction fragment length polymorphism |
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Definition
| genetic analysis using broken dna and electrophoresis |
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| variable number tandem repeats |
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Definition
| genetic analysis that looks at the unique pepetitive DNA that is different in every person |
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Term
| fluorescence activated chromosome sorting |
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Definition
| genetic analysis that isolates human chromosomes and can introduce it to other species to see if it's expressed |
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Definition
| irradiation cells and fragmenting dna to observe linkage |
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Definition
| genetic analysis using electrophoresis and probe hybridization |
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Definition
| exact replica of a biological entity |
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Definition
| multiple copies of a single DNA sequence |
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Definition
| DNA cloning vehicle which is it self DNA |
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Definition
| process of introducing recombinant plasmids to the new host throught their cell walls |
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Definition
| determines ability of gene to grow |
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Definition
| three popular cloning vehicles |
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Definition
| single stranded DNA phage |
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Definition
| hybrid plasmid used as a vector with cohesive sites from lambda phage |
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| bacteria artificial chromosomes BACs |
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Definition
| cloning vehicles based on e coli F factor |
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Term
| Yeast artificial chromosomes YACs |
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Definition
| linear vectors with yeast telomere ends |
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Definition
| uses to allow bacteria to produce foreign DNA gene products eg insulin |
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Term
| Polymerase Chain Reaction |
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Definition
| a scientific technique in molecular biology to amplify a single or a few copies of a piece of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence. |
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Definition
| heat tolerant enzyme that catalyzes polymerase chain reaction |
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Definition
| well known for its ability to transfer DNA between itself and plants; made to produce BT (pesticide) |
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Definition
| vector that grows well in two different species of host; |
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Definition
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| cloning entire genome at once |
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Definition
| polymerase chain reaction is a type of |
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Definition
| organism with cells made up of foreign DNA usually for commercial purposes |
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| same person that receives benefit should receive the risk |
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Definition
| gene therapy hippocratic oath |
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Definition
| a discipline in genetics concerning the study of the genomes of organisms |
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Definition
| characterizing the physical nature of the genome |
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Definition
| characterizing the transcripts and proteins the genome produces |
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Term
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Definition
| corepressor adds to the _______ to turn off operon |
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Term
| positive, cAMP-CAP, negative, inducer, repressor |
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Definition
| lac operon operates either with the ______ regulation using ______ or the ________regulation where lactose, the _______ binds to the ______ |
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Term
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Definition
| protein encoded in lac operon that breaks down lactose into sugars for metabolism |
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Definition
| lets lactose into e coli more easily |
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Definition
| sum of all alleles in a population at a given time |
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Definition
| proportions of given alleles |
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Definition
| analyzing allele frequency over time |
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Definition
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| fitness, 1-s (selection coefficient) |
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Definition
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Definition
| selection coefficient p2+2pq+q2_____ |
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Term
| Sewall Wright, inbreeding coefficient |
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Definition
| population geneticist that thought of F, _____ |
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Definition
| increase homozygosity in a population |
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| kills homozygosity in a population |
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| improved health of heterozygote; heterosis |
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| less deleterious recessives and overdominance |
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Definition
| 2 reasons for hybrid vigor |
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Definition
| central paradigm for modern biology |
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Definition
| gene pool is separated and changes from one another |
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Definition
| n gene pairs binomial equation |
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Term
| meristic liability threshold |
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Definition
| memorize these three words they may come in handy |
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Definition
| disc. genes on chromosomes |
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| hypothesized barr body = inactivated x |
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Definition
| disc. gene pairs inherited together, separation of genes via crossing over |
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| his experiment discovered transformation |
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Definition
| their experiment showed that DNA was the transforming principle |
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| found that DNA not protein was genetic material |
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| Meselson-Stahl experiment |
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Definition
| experiment that disproved conservative and dispersive models |
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Definition
| studied ingredients for DNA replication |
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Definition
| used heavy hydridine to enlarge DNA and see two replicating forks |
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| one gene - one enzyme hypothesis/experiment |
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