Term
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Definition
genes located close together on the same chromosome
travel together during meiosis, end up in the same gamete, do not usually sort independently |
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Term
| nonrecombinant (parental) gamete |
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Definition
| contains only the original combinations of genes present in the parents |
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Term
| nonrecombinant (parental) progeny |
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Definition
| possesses the original combinations of traits possessed by the parents |
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Term
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Definition
| possesses a new combination of genes |
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Term
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Definition
| possesses a new combination of traits formed from recombinant gametes |
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Term
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Definition
proportion of recombinant progeny produced in a cross
(number of recombinant progeny/total number of progeny) x 100 |
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Term
| coupling (cis) configuration |
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Definition
| arrangement in which two or more wild type genes are on one chromosome and their mutant alleles are on the homologous chromosome |
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Term
| repulsion (trans) configuration |
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Definition
| arrangement in which each chromosome contains one wild type (dominant) gene and one mutant (recessive) gene |
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Term
| interchromosomal recombination |
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Definition
| recombination among genes on different chromosomes |
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Term
| intrachromasomal recombination |
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Definition
| recombination among genes on the same chromosome |
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Term
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Definition
map of the relative distances between genetic loci, markers, or other chromosome regions determined by rates of recombination
measured in percent recombination or map units |
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Term
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Definition
map of physical distances between loci, genetic markers, or other chromosome segments
measured in base pairs |
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Term
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Definition
unit of measure for distances on a genetic map
1 map unit = 1% recombination = 1 centimorgan |
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Term
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Definition
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Term
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Definition
a testcross between two genes
cross between an individual heterozygous at two loci and an individual homozygous for recessive alleles at those loci |
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Term
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Definition
a testcross between three genes
cross between an individual heterozygous at three loci and an individual homozygous for recessive alleles at those loci |
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Term
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Definition
the degree to which one crossover interferes with another
1 - coefficient of coincidence |
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Term
| coefficient of coincidence |
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Definition
observed double crossovers / expected double crossovers
if you see exactly as many as expected, cc=1 int=0
if you see more than expected, cc=(+) int=(-)
if you see none, cc=0 int=1 |
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Term
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Definition
| relates recombination frequencies to actual physical distances between genes |
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Term
| lod (logarithm of odds) score |
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Definition
logarithm of the ratio of the probability of obtaining a set of observations, assuming a specified degree of linkage, to the probability of obtaining the same set of observations with independent assortment
used to assess the likelihood of linkage between genes from pedigree data
a LOD score greater than 3.0 is considered evidence for linkage |
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Term
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Definition
| any gene or DNA sequence used to identify a location on a genetic or physical map |
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Term
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Definition
| technique for determining the chromosomal location of a gene by studying the association of its phenotype or product with particular chromosome deletions |
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Term
| somatic-cell hybridization |
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Definition
| fusion of different cell types |
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Term
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Definition
| genetically identical cells that divide indefinitely and can be cultured in the laboratory |
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Term
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Definition
| cell possessing two nuclei derived from different cells through cell fusion |
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Term
| THERE IS NO RECOMBINATION IN DROSOPHILIA (FLIES) |
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Definition
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