Term
| Concordance is a calculation of heritability in ____________ |
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Definition
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Term
| True or False: In studying the variation of a phenotype in a population, you notice that the distribution follows a bell-shaped curve. This suggests to you that this trait is most likely a polygenic trait. |
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Definition
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Term
| As a researcher, you wish to study individuals that shared a common environment growing up, but had different genetics. What kind of twins would you pick? |
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Definition
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Term
| The phenotypes of skin color and fingerprints are examples of _______. |
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Definition
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Term
| What equation describes a multifactorial trait? |
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Definition
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Term
| A polymorphism is a genetic difference that exists in at least _____ % of the population (enter a whole number |
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Definition
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Term
| True or False: In the study of medicine, there is a direct correlation between the color of a person's skin and their susceptibility to certain medicines. |
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Definition
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Term
| Alu polymorphisms have been used to study what? |
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Definition
| The genetic basis of humans |
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Term
| Coefficients of relatedness would be highest in what relationship pair? |
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Definition
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Term
| How many Barr bodies would the cells of an XXX female contain? |
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Definition
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Term
| Transcription factors act as on/off switches for ____________. |
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Definition
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Term
| True or False: In sex-influenced inheritance, the phenotype of a heteroxygous male and a heterozygous female differ. |
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Definition
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Term
| In a x-linked recessive trait, males will receive the recessive allele from __________. |
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Definition
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Term
| True or False: The pseudoautosomal regions (PAR) of the X and Y chromosomes are what make them homologous, and allow them to pair up during meiosis. |
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Definition
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Term
| gene thats responsible for "counting" the number of X chromosomes? |
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Definition
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Term
| What sex determination systems is the female the heterogametic sex? |
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Definition
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Term
| What code is a transcription factor that regulates male development? |
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Definition
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Term
| True or False: In humans, all of the genes needed for sexual development are located on either the X or Y chromosome. |
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Definition
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Term
| Methylation is involved in _____________. |
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Definition
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Term
| An epistatic interaction between two genes in an AaBb x AaBB cross that produces a 12:3:1 phenotypic ratio is an example of ________ epistasis. |
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Definition
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Term
| An epistatic interaction between two genes in an CcDd x CcDd cross that produces a 9:3:4 phenotypic ratio in the offspring is an example of ________ epistasis. |
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Definition
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Term
| In humans, mitocondria are inherited from which parent? |
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Definition
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Term
| VNTRs, STRs and SNPs are examples of ____________. |
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Definition
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Term
| Haplotype analysis uses what as markers? |
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Definition
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Term
| A haplotype analysis is used to ______________. |
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Definition
| identify a region of a chromosome that is associated with a disease or trait |
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Term
| A map unit is equal to __________. |
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Definition
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Term
| Name 3 syndromes that result from Imprinting? |
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Definition
| ANGLEMAN SYNDROME (Chromosome 15, maternally imprinting, ubiquitin gene is deleted, small happy kids die at ten) , PRADER-WILLI syndrome (paternally inherited, obese kids) , and BECKWITH SYNDROME (paternally inherited, chromosome 11 is tumor suppressor, internal organs covered in tumors) |
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Term
| what does FISH stand for? |
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Definition
| Fluorescence In Situ Hybridization (makes chromosomes pretty) |
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Term
| Formulas for Mendelian, Polygenic, Multifactorial |
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Definition
Mendelian: Vt = Vg
Polygenic: Vt= sum of Vg1+ Vg2 + Vg3....etc
Multifactorial: Vt = Ve + Vg |
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Term
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Definition
Cells w/ extra or missing chrmosomes.
2n+ 1 = trisomy
2n- 1 = monosomy |
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Term
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Definition
| This is a X-linked Recessive Trait |
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Term
| A cross of two AaBb genotypes yields a phenotypic ratio of 12:3:1. What type of epistatic interaction is this? |
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Definition
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Term
| A cross of two AaBb genotypes yields a phenotypic ratio of 9:3:4. What type of epistatic interaction is this? |
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Definition
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Term
| Heteroplasmy is associated with____ |
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Definition
| mitochondrial inheritance |
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Term
| haplotypes uses ______ as markers |
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Definition
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Term
| In order for a genetic marker to be considered as linked to a gene of interest, the LOD score must exceed: |
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Definition
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Term
| In linkage mapping, 1 map unit is equal to |
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Definition
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Term
| the SRY gene encodes for_____ |
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Definition
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Term
| During male development, remaining female reproductive structures are removed by the process of ____ |
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Definition
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Term
| In an X-linked dominant trait, an affected male would produced: |
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Definition
| 100% affected female children |
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Term
| What determines gender in humans? |
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Definition
| the SRY region on the Y chromosome |
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Term
| In the ZZ-ZW system, which sex is heterogametic? |
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Definition
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Term
| The amount of phenotypic variability that is due to genetics is called _________ |
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Definition
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Term
| The formula Vt = Vg + Ve is an example of ______ trait. |
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Definition
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Term
| What type of twin removes Vg from the equation Vt = Vg + Ve? |
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Definition
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Term
| Single nucleotide polymorphisms (SNPs) are most often used _______ |
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Definition
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Term
| Population has a heritability value of 0.86 for a certain disease, while population B has a heritability value of 0.41. Which population has a greater genetic contribution? |
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Definition
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Term
| Term that assumes that there are multiple genes, but no environmental component |
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Definition
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Term
| Trait that is most likely not multifactorial? |
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Definition
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Term
| True or False: methylation is a process by which chromosomes are inactivated |
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Definition
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Term
| formula that represents a karyotype that has an extra copy of chromosome 13? |
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Definition
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Term
| Syndrome that can be produced by both a translocation event and a aneuploid condition |
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Definition
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Term
| What can you deduce from chromosome location 7q19. |
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Definition
| It is on chromosome 7, it is on the long arm of chromosome, it is the ninth minor band of the first major band. |
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Term
| Syndrome that can only be produced by a non-disjunction in a male |
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Definition
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Term
| Common name for trisomy-13? |
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Definition
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Term
| What is the correct notation for Turner syndrome? |
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Definition
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Term
| True or False: A chromosome that is numbered 4 is larger than a chromosome that is numbered 9? |
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Definition
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Term
| True or false: the majority of the genes on a chromosome are contained in the heterochromatin areas of the chromosome |
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Definition
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Term
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Definition
| Edward Syndrome. massive heart problems. most infants die |
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Term
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Definition
| klinfelter syndrome. small penises, long limbs and hands |
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Term
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Definition
| Jacobs syndrome. Great height, acne, speech problems and reading disabilities |
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Term
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Definition
-Common Cause of aneuploidy
-chromosomes not pulled apart correctly during anaphase.
-MEIOSIS 1 = copies of both homologs in 1 gamate
-MEIOSIS 2 = copies of both sister chromatids in 1 gamate |
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