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Genetics Chap 02
Chromosomes and Cellular Reproduction
28
Biology
Undergraduate 4
02/09/2010

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Term
Homologous Pair of Chromosomes
Definition
Two chromosomes that are alike in structure and size and that carry genetic information for the same set of hereditary characteristics. One chromosome of a homologous pair is inherited from the male parents and the other is inherited from the female parent.
Term
Haploid
Definition
Possessing a single set of chromosomes.
Term
Diploid
Definition
Possessing two sets of chromosomes (two genomes).
Term
Centromere
Definition
The attachment point for spindle microtubules.
Term
Spindle Microtubules
Definition
The filaments responsible for moving chromosomes during cell division.
Term
Kinetochore
Definition
Set of proteins that assemble on the centromere, providing the point of attachment for spindle microtubules.
Term
Telomere
Definition
The natural ends of a linear chromosome; serve to stabilize chromosome ends.
Term
Origins of Replication
Definition
The sites where DNA synthesis begins.
Term
Sister Chromatids
Definition
Two copies of a chromosome that are held together at the centromere; each chromatid consists of a single DNA molecule.
Term
Interphase
Definition
The first major phases of the cell cycle; the period between cell divisions in which the cell grows, develops, and prepares for cell division.
Term
G1 Phase
Definition
The cell grows and proteins necessary for cell division are synthesized.
Term
S Phase
Definition
DNA synthesis, in which each chromosome duplicates.
Term
G2 Phase
Definition
Several additional biochemical events necessary for cell division take place.
Term
M Phase
Definition
The part of the cell cycle in which the copies of the cell's chromosomes (sister chromatids) separate and the cell undergoes division; includes prophase, prometaphase, metaphase, anaphase, and telophase.
Term
Prophase
Definition
Chromosomes condense; the mitotic spindle forms.
Term
Prometaphase
Definition
Disintegration of the nuclear membrane; spindle microtubules enter the nuclear region and make contact with the chromosomes.
Term
Metaphase
Definition
The chromosomes become arranged in a single plane (the metaphase plate) between the two centrosomes, which center at the spindle poles.
Term
Anaphase
Definition
Sister chromatids separate and move toward opposite spindle poles.
Term
Telophase
Definition
Chromosomes arrive at the spindle poles; nuclear membrane re-forms around eat set of chromosomes; cytokinesis is usually simultaneous.
Term
Meiosis
Definition
Leads to gamets in which chromosome number is reduced by half; consists of prophase I to telophase I, interkinesis, and prophase II to telophase II.
Term
Fertilization
Definition
Two haploid gametes fuse and restore chromosome number to its original diploid value.
Term
Crossing Over
Definition
Homologous chromosomes exchange genetic information.
Term
Chiasmata
Definition
Site of crossing over in meiosis.
Term
Recombination
Definition
Creating new combinations of alleles on a chromatid.
Term
Cohesin
Definition
A protein that holds the chromatids together; key to the behavior of chromosomes in mitosis and meiosis.
Term
Spermatogenesis
Definition
The production of gametes in a male animal; takes place in the testes and results in four haploid sperm.
Term
Oogenesis
Definition
The production of gametes in a female animal; results in a single haploid ovum.
Term
Polar Body
Definition
In oogenesis, contains half of the chromosomes but a small amount of the cytoplasm.
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