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Genetics 160 Vocab
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Undergraduate 1
09/17/2009

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Term
Allele
Definition
Alternative form of a gene.
Term
Dominant
Definition
A gene that expresses itself even when heterozygous. Also, the trait controlled by that allele.
Term
Recessive
Definition
An allele (or phenotype) that does not express itself in the heterozygous condition.
Term
Monohybrid
Definition
Offspring of parents that differ in only one genetic characteristic. Usually implies heterozygosity at a single locus under study.
ex. Bb x Bb
Term
Dihybrid
Definition
An organism that is heterozygous at two different loci.
ex. RrYy
A cross involving two pairs of contrasting characters.
Term
Test cross
Definition
The cross of an organism with a homozygous recessive organism.
Term
Genotype
Definition
The genes an organism possesses.
Term
Homozygous
Definition
A diploid or polyploid with identical alleles at a locus.
ex. AA
Term
Heterozygous
Definition
A diploid or polyploid with different alleles at a particular locus.
ex. Aa
Term
Phenotype
Definition
The observable traits of an organism.
Term
Gamete
Definition
A germ cell having a haploid chromosomal complement. Gametes from parents of opposite sexes fuse to form zygotes. They carry half the genetic information of an organism and are formed by meiosis.
Term
Diploid
Definition
An organism having two copies of each chromosome per nucleus or cell.
Term
Haploid
Definition
The state of having one copy of each chromosome per nucleus or cell.
Term
Karyotype
Definition
The chromosome complement of a cell. AKA- What chromosomes you got. Often displayed as a map/graph/pretty pictures!
Term
Centromere
Definition
Constrictions in eukaryotic chromosomes on which the kinetochore lies. Also, the DNA sequence within the constriction that is responsible for binding the kinetochore. AKA- Where the X of the chromosome shape comes together.
Term
Chromatid
Definition
The DNA-protein structure that corresponds to one double-stranded DNA molecule. At anaphase of meiosis II or mitosis, when the sister chromatids separate, each chromatid becomes a chromosome.
Term
Metacentric
Definition
When the centromere is located in the center of the chromosome.
Term
Submetacentric
Definition
When the centromere is located between the center and the end of the chromosome.
Term
Acrocentric
Definition
When the centromere is located at the very end of the chromosome.
Term
Telomere
Definition
The ends of linear eukaryotic chromosomes.
Term
Kinetochore
Definition
A complex of proteins that are associated with the centromere and attaches to the spindle fibers.
Term
Spindle fibers/Kinetochore microtubules
Definition
Microtubules radiating from the centrosome and attached to kintochores of chromosomes during mitosis and meiosis.
Term
Centrosome
Definition
The spindle-microtubule organizing center in eukaryotes that uses spindle pole organizing bodies to organize the spindles. (this definition is straight from the book).
Term
Homolog
Definition
One member of a chromosome pair
Term
Bivalent
Definition
Structures, formed during prophase of meiosis I, consisting of the synapsed homologous chromosomes.
A bivalent is a pair of associated homologous chromosomes formed after replication. Each replicated chromosome comprises two chromatids.
Term
Cohesin
Definition
Cohesin is the protein complex responsible for binding the sister chromatids during synthesis through the G2 phase and into mitosis phase. When two sister chromatids are bound along their lengths by cohesin, the attachment is referred to as sister chromatid cohesion.
Term
Reductional division
Definition
The first meiotic division that reduces the number of chromosomes and centromeres to half relative to the original cell.
Term
Chiasma
Definition
A chiasma (plural: chiasmata), in genetics, is thought to be the point where two homologous non-sister chromatids exchange genetic material during chromosomal crossover during meiosis.
Term
Linkage Group
Definition
Associations of loci on the same chromosome.
A pair or set of genes on a chromosome that tend to be transmitted together.
Term
Disjunction
Definition
The separation of the homologs in meiosis I.
Term
Nondisjunction
Definition
Nondisjunction is the failure of chromosome pairs to separate properly during cell division. This could arise from a failure of homologous chromosomes to separate in meiosis I, or the failure of sister chromatids to separate during meiosis II or mitosis. The result of this error is a cell with an imbalance of chromosomes.
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