Term
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Definition
halogenated hydrocarbons (inhaled)
-decrease in minute volume (++)
-skeletal muscle relaxation (++)
-clinical use (+++) |
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Term
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Definition
halogenated hydrocarbons (inhaled)
-high MAC -> slow induction
-sensitization of myocardium to catecholamines -> arrythmias
-myocardial function: depressed sympathetic stimulation (++)
-severe hepatitis
-cerebral flow increased (++) |
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Term
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Definition
halogenated hydrocarbons (inhaled)
-changes in renal concentration ability
-myocardial function: depressed sympathetic stimulation (++)
-decrease in minute volume (++)
-skeletal muscle relaxation (+++) |
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Term
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Definition
halogenated hydrocarbons (inhaled)
-nephrotoxic due to inorganic fluoride released during metabolism
-clinical use (+++) |
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Term
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Definition
halogenated hydrocarbons (inhaled)
-clinical use (+++) |
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Term
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Definition
inhaled
-low MAC -> fast induction
-low anesthetic potency
-marked analgesia, amnesia
-clinical use (+++) |
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Term
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Definition
short-acting barbituates (intravenous)
-bolus dose or IV drip
-rapid onset (~30sec), very short anesthesia (10min)
-rapid diffusion out of brain and redistribution; slow liver metabolism -> hangover
-myocardial and respiratory depressant
-decreased cerebral blood flow -> good for pts with head injuries, brain tumors
-may reduce hepatic blood flow, GFR
-not analgesic |
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Term
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Definition
benzodiazepine (intravenous)
-slower onset of central action
-sedative but central depression below true anesthesia
-prolong recovery
-anterograde amnesia -> given before induction (premedication)
-minimal respiratory or CV depression
-not analgesic |
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Term
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Definition
opioids (intravenous)
-analgesic, only large dose anesthetic
-little effect on circulation
-respiratory depression (severe with high dose)
-effects can be reversed by naloxone (opioid antagonist)
-sufentanil is 5-10x more potent than fentanyl |
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Term
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Definition
intravenous
-most popular IV anesthetic
-rapid onset, rapid recovery
-feels better
-hypotension
-respiratory depressant
-ANTIEMETIC
-pain at site of injection; ~expensive |
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Term
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Definition
intravenous
-rapid onset, loss of consciousness within seconds
-recovery occurs in 3-5 min
-minimal CV and respiratory depression
-no analgesic effects, requires premedication
-high incidence of nausea, vomiting, pain on injection |
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Term
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Definition
intravenous
-catatonia, amnesia, analgesia
-blocks glutamate (NMDA) receptors
-CV stimulation: increases HR, BP, CO
-increases cerebral blood flow, intracranial pressure
-little respiratory depression
-post-op disorientation, illusions, vivid dreams -> so little used in US |
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