Term
| Target cells of Canavan Disease |
|
Definition
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|
Term
| incidence of cystic fibrosis |
|
Definition
|
|
Term
| target cells of hemophilia |
|
Definition
| liver, muscle, bone marrow cells |
|
|
Term
|
Definition
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|
Term
| defect in canavan disease |
|
Definition
| aspartoacylase deficiency, myelin degneration |
|
|
Term
| disadvantage of using retrovirus |
|
Definition
infects dividing cells only
random integration |
|
|
Term
| benefit to using Herpesvirus |
|
Definition
| infects non-dividing cells |
|
|
Term
| Adeonvirus: Advantage and disadvantage |
|
Definition
Adv: infects non-dividing cells
Dis: does not integrate into host genome
stimulates immune response |
|
|
Term
|
Definition
3 nucleotide deletion- delta508 loss
3 liposomes
1 adenovirus
1AAV as delivery vector |
|
|
Term
|
Definition
Not immunogenic; no limit on size
LOW expression though
attacked by body
LOW specificity |
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|
