Term
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Definition
| CENTRAL ACTING EMETIC. STIMULATES DOPAMINE RECEPTORS IN CRTZ. ALSO STIMULATES OPIOD RECEPTORS. CAN CAUSE RESPIRATORY DEPRESSION & SEDATION. |
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Term
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Definition
| CAN REVERSE SIDE EFFECTS OF APOMORPHINE |
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Term
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Definition
| DOPAMINE ANTAGONIST. PHENOTHIAZINES. REVERSE VOMITING FROM APOMORPHINE. |
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Term
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Definition
| ALPHA-2 AGONIST. CENTRAL ACTING EMETIC. STIMULATES ALPHA RECEPTORS IN CRTZ & VOMITING CENTER. SERIOUS CARDIOVASCULAR EFFECTS |
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Term
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Definition
| IRRITANT TO INTESTINAL MUCOSA. TAKEN OFF MARKET '04. CARDIOTOXIC- NEVER REDOSE! |
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Term
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Definition
| GASTRIC IRRITANT. RISK ASPIRATION. MAY REPEAT ONCE. INCONSISTENT RESPONSE. LOCAL ACTING EMETIC |
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Term
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Definition
| TABLE SALT. STIMULATES VAGUS NERVE. ENSURE H20/FLUIDS. |
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Term
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Definition
| PASSIVE RETROGRADE (BACKWARDS) MOTION OF INGESTA B4 IT REACHES STOMACH |
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Term
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Definition
| BLOCK DOPAMINE RECEPTORS IN CRTZ AND VOMITING CENTER. ALSO BLOCKS HISTAMINE RECEPTORS. ACEPROMAZINE, CHLORPROMAZINE, PROCHLORPERAZINE. CAN CAUSE HYPOTENSION, SEDATION, LOWERS SEIZURE THRESHOLD |
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Term
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Definition
| USED FOR MOTION SICKNESS, ANTIEMETIC, BLOCKS H1 RECEPTORS IN THE CRTZ. DIPHENHYDRAMINE, DIMENHYDRINATE, MECLIZINE. EFFECTS VARY. |
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Term
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Definition
| PARASYMPATHOLYTICS: ATROPINE, AMINOPENTAMIDE (CENTRINE®); BLOCK THE VAGUS NERVE; DECREASE SECRETIONS, MOTILITY; MAY ACTUALLY INCREASE VOMITING D/T GI |
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Term
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Definition
| PROKINETIC DRUG; CENTRAL EFFECT- INHIBITS DOPAMINE & SEROTONIN RECEPTORS IN CRTZ; LOCAL EFFECT- STIMULATES MOTILITY IN UPPER GI TRACT; TIGHTENS LOWER ESOPHAGEAL SPHINCTER; DO NOT COMBINE W/ PHENOTHIAZINES, ANTICHOLINERGICS OR OPIATES; S.E. SEDATION, MANIC BEHAVIOR IN CATS; BILIOUS VOMITING; |
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Term
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Definition
| BILE FROM DUODENUM LEAKING BACK INTO THE STOMACH THRU PYLORUS. TX: METOCLOPRAMIDE @ BEDTIME |
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Term
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Definition
| ANTIEMETIC; ZOFRAN®; NOT APPROVED IN ANIMALS, BLOCKS SEROTONINE RECEPTORS IN CRTZ. $$$ |
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Term
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Definition
| CERENIA®; DOGS >16WKS; NO SEDATION; NEUROKININ-1 RECEPTOR ANTAGONIST, CENTRAL ACTING BLOCKS SUBSTANCE P |
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Term
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Definition
| INCREASE SEGMENTATION, DECREASE PERISTALSIS, SLOWS TRANSIT TIME; DECREASE SECRETIONS INTO INTESTINAL LUMEN |
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Term
| DIPHENOXYLATE ( LOMOTIL®) |
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Definition
| CONTROLLED CLASS V OPIOD ANTIDIARRHEAL |
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Term
CAMPHORATED TINCTURE OF OPIUM
(PAREGORIC®) |
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Definition
| CONTROLLED OPIOD ANTIDIARRHEAL, CLASS III |
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Term
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Definition
| (IMMODIUM A-D®), OTC, OPIOD ANTIDIARRHEAL |
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Term
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Definition
| INCREASES SEGMENTAL CONTRACTIONS IN THE PROXIMAL SMALL INTESTINE |
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Term
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Definition
BLOCK PNS; DANGEROUS IN PATIENTS WITH HYPERTHYROIDISM, CARDIAC;
OLD SCHOOL: STOP INTESTINES
NEW SCHOOL: WORSEN DIARRHEA |
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Term
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Definition
ATROPINE
AMINOPENTAMIDE (CENTRINE)
METHSCOPALAMINE
PROPANTHELINE |
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Term
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Definition
| ENTEROTOXINS OR INFLAMMATORY PROSTAGLANDINS STIMULATE CELLS LINING GI TRACT-> OSMOTICALLY ACTIVE IONS DUMPED INTO INTESTINAL LUMEN-> PULL H20 WITH |
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Term
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Definition
BISMUTH= PROTECTANT OF MUCOSA
SALICYLATE= BLOCKS PROSTAGLANDIN PRODUCTION-> DECREASES INFLAMMATORY RESPONSE
PRECAUTIONS: RADIOPAQUE, LOOKS LIKE MELENA, USE IN CATS <24H, INTERFERES W/ ABSORPTION OTHER DRUGS,
PEPTO-BISMOL, KAOPECTATE |
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Term
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Definition
BANAMINE®
NSAID
ANALGESIC USED TO BLOCK EFFECT OF BACTERIAL TOXINS, HORSES= COLIC; CALF SCOURS
SE: DOGS-> GI ULCERATION, CATS-> RENAL FAILURE |
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Term
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Definition
SULFA ANTIBIOTIC COMBINED W/ SALICYLATE,
BACTERIA CLEAVE BOND
SULFA=DOES LITTLE GOOD
SALICYLATE (MESALAMINE) = ANTIINFLAMMATORY, ASPIRIN COMPOUND |
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Term
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Definition
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Term
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Definition
KAO-PECTATE®
INTERFERES W/ ABSORPTION OF OTHER DRUGS
QUESTIONABLE EFFICACY
NEW FORMULA HAS BISMUTH SUBSALICYLATE
PROTECTANT |
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Term
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Definition
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Term
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Definition
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Term
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Definition
RELIEVE CONSTIPATION
TRICHOBEZOAR PASSAGE
SOFTEN STOOL |
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Term
| LUBRICANT EMOLLIENT LAXATIVE |
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Definition
COAT THE STOOL FOR EASIER PASSAGE
MINERAL OIL-HORSES
GLYCERIN SUPPOSITORIES
LUBRICANTS |
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Term
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Definition
| LUBRICANT EMOLLIENT LAXATIVES; WHIT PETROLATUM, COD LIVER OIL; WITH CHRONIC USE INTERFERE W/ ABSORPTION OF FAT-SOLUBLE VITAMINS (ADEK) |
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Term
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Definition
BRAN, PSYLLIUM (METAMUCIL®)
PUMPKIN; INDIGESTIBLE FIBER: NOT ABSORBED FROM GI TRACT; FIBER RETAINS H20 IN FECES; OSMOTIC |
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Term
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Definition
EVACUATE THE COLON
INCREASE PERISTALSIS D/T IRRITATION OF THE BOWEL
CASTOR OIL
NOT COMMONLY USED |
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Term
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Definition
OSMOTIC CATHARTICS
EPSOM SALTS, MILK OF MAGNESIA®,
OSMOTIC AGENTS
HIGH DOSE Mg=TOXICITY: ELECTOLYTE DISTURBANCE-> MUSCLE WEAKNESS, CNS ALTERATIONS |
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Term
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Definition
POORLY ABSORBED- STAYS IN GI TRACT
USED FOR CHRONIC CONSTIPATION, HEPATIC ENCEPHALOPATHY
ACIDIFIES COLON CONTENTS SO AMMONIA CAN'T BE ABSORBED AS WELL |
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Term
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Definition
| POOR FUNCTIONING LIVER->ABSORPTION OF BACTERIAL AMMONIA FROM GI TRACT INTO SYSTEMIC CIRCULATION INSTEAD OF BEING DETOXIFIED IN LIVER |
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Term
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Definition
PHOSPHAE ENEMAS- FLEET®= DANGEROUS IN CATS/SMALL DOGS-> HYPOCALCEMIA=DEATH
WARM H20
DSS ENEMA |
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Term
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Definition
PROKINETIC DRUG
AVAILABLE THRU COMPOUNDING PHARMACIES |
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Term
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Definition
TUMS, AMPHOGEL, ROLAIDS, MAALOX
SALTS OF Ca, Mg, Al
CHEMICALLY NEUTRALIZE GASTRIC ACID MOLECULES- DON'T USE RECEPTORS
PROBS: Ca & Al= CONSTIPATION; Mg= DIARRHEA
ELECTROLYTE IMBALANCE IF ABSORBED, ACID REBOUND INTERFERE W/ ABSORPTION=SEPARATE |
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Term
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Definition
CALCIUM CARBONATE CAUSES GASTRIN RELEASE-> HCL SECRETION
HIGHER THAN B4 TX |
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Term
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Definition
ABSORBED, DISTRIBUTED
DECREASE ACID PRODUCTION IN STOMACH
PARIETAL CELLS (HISTAMINE, ACETYLCHOLINE, GASTRIN) |
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Term
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Definition
SYSTEMIC ANTACID, COMPETITICE INHIBITIONOF H2 RECEPTORS;
BLOCK SECRETION OF HCL
-CIMETIDINE (TAGAMENT)
-RANITIDINE (ZANTAC)
-FAMOTIDINE (PEPCID)
OTC DRUGS; STAGGER DOSE W/ DRUGS RELYING ON GASTRIC ACIDITY; METABOLIZED BY LIVER
IV, IM, SQ, PO
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Term
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Definition
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Term
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Definition
SYSTEMIC ANTACID
BINDS TO LUMINAL SURFACEOF STOMACH-> PROTON PUMP INHIBITOR; INHIBITS SECRETION OF H+ INTO STOMACH LUMEN
PRILOSEC®, LOSEC®, GASTROGARD® |
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Term
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Definition
ANTIULCER DRUG
SELECTIVELY BINDS TO ULCERATED AREAS OF GI TRACT & PROTECTS FROM FURTHER DAMAGE (BAND-AID)
STIMULATES PgE SYNTHESIS
NOT ABSORBED
WORKS BEST IN ACIDIC ENVIRONMENT, SEPARATE DOSE FROM OTHER DRUGS, NOT METABOLIZED |
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Term
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Definition
ANTIULCER,
CYTOTEC®
SYNTHETIC PROSTAGLANDIN E
PROTECTS GASTRIC MUCOSA- INCREASES PROTECTIVE MUCOSA PRODUCTION, BLOOD SUPPLY TO MUCOSA, MUCOSAL TURNOVER, INHIBIT GASTRIC ACID SECRETION
SE: DIARRHEA, ABDOMINAL DISCOMFORT, CRAMPING, UTERINE CONTRACTIONS, COLIC D/T INCREASE GI MOTILITY |
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Term
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Definition
FATTY LIVER DZ
MOST COMMON = CATS
ANOREXIA-> MOBILIZE BODY FAT->FAT ACCUMULATES IN LIVER-> SEVERE CHOLESTASIS & LIVER FAILURE
UNKNOWN CAUSE
CLINICAL SIGNS: WT LOSS, ANOREXIA, +/- JAUNDICE, +/- VOMITING, DEHYDRATION;
TX: AGGRESSIVE FEEDING |
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Term
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Definition
APPETITE STIMULATE
PERIACTIN®
H1 ANTIHISTAMINE W/ SEROTONIN ANTAGONIST PROPERTIES
USED IN FELINE ASTHMA, URI
TAKE UP TO 24 HRS TO WORK
80 % CATS
SE OF ANTIHISTAMINES (DROWSINESS OR MANIC BEHAVIOR) |
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Term
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Definition
APPETITE STIMULANT
IV-> IMMEDIATE RAVENOUS KITTY
PO: INCREASE APPETITE (CATS ONLY)
CAN CAUSE LIVER FAILURE |
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Term
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Definition
ANTI-BLOAT
STIMULATE ATONIC OR FLACCID RUMEN
MERCURYM STRYCHNINE, TARTAR, PLANT CONCOTIONS
NEOSTIGMINE: PREVENTS ACETYLCHOLINESTERASE FORM BREAKING DOWN ACETYLCHOLINE-> INCREASE PNS SIGNS, NOT COMMONLY USED
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Term
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Definition
ERUCTATION
RUMINAL TYMPANY- RUMEN UNDER PRESSURE
FROTHY BLOAT
DSS, MINERAL OIL, DETERGENTS |
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Term
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Definition
TYLAN®
ANTIMICROBIAL
MACROLIDE ANTIBIOTIC; USED IN CATTLE & SWINE TO TREAT GI INFECTIONS
CONTRAINDICATED IN HORSES
OFF-LABEL DOGS & CATS |
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Term
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Definition
SELECTIVELY KILLS ANAEROBES (CLOSTRIDIA); PROTOSOANS (GIARDIA)
ANTIINFLAMMATORY EFFECT ON COLON
TASTES FOUL
TOXICITY= IATROGENIC CAUSE OF NEUROLOGICAL PROBS, RESOLVE WHEN D/C
CAUTION W/ LIVER OR RENAL DZ, NOT USED IF PREGANT |
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Term
PANCREATIC
ENZYME
SUPPLEMENTS |
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Definition
EXOCRINE PANCREATIC INSUFFICIENCY= VOLUMINOUS, PALE, GREASY STOOL
REPLACE- HOG PANCREAS
POWDER FORM
PANCREAZYME, VIOKASE-V |
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Term
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Definition
IBD
SE: IMMUNOSUPPRESSION, INCREASE GASTRIC ACIDITY, PROSTAGLANDIN SUPPESSION, DECREASED HEALING, INCREASED RISK OF INFECTION |
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