Term
| What is the action of antihistamines? |
|
Definition
Is to block or inhibit the action of histamine.
Or
Antihistamines compete with histamine for the receptor sites so that action of histamine can be blocked.
Note: Anithistamines DO NOT prevent histamine release or reduce the amount released. |
|
|
Term
| Antihistamines reduce what effect? |
|
Definition
Vasodilation, contraction of the smooth muscles, increased GI and respiratory secretions, increased capillary permeability, increased heart rate and CNS transmission.
Or
Antihistamines inhibit smooth muscle contraction, vascular permeability, and edema formation and decrease capillary permeability, decrease salivation, and tear formation, |
|
|
Term
| Antihistamines cause the bronchial smooth muscles to relax or contract? |
|
Definition
|
|
Term
| Anithistamines are indicated for allergic rhinitis, allergic conjunctivitis, allergic dermatitis, vertigo, motion sickness, insomnia, allergic reactions, cough, sneezing, and a runny nose due to the common cold; what is the action of the body regarding the above? |
|
Definition
| Reduce bronchial, salivary, gastric, nasal, and lacrimal (tear) secretions and reduce itching (urticaria) |
|
|
Term
| Anithistamines are used for the prevention and treatment for allergic reactions to medications, what is the most life-threatening allergic reaction that anit-histamines treat? |
|
Definition
|
|
Term
| Diphenhydramine is Selected First-generation antihistamine, what receptor do they bind to? |
|
Definition
|
|
Term
| Antihistamines are classified as? |
|
Definition
|
|
Term
| Traditional histamines have sedative or stimulative effects, why is this? |
|
Definition
H1 receptor antagonists bind to central and peripheral H1 receptors.
CNS depression or sedation: usually in high doses
Stimulation: anxiety or agitation |
|
|
Term
| H1 receptor antagonist have anticholinergic effects, such as? |
|
Definition
| Dry mouthm urinary retention, constipation, and blurred vision. |
|
|
