Term
| G-protein coupled receptors |
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Definition
indirectly regulate the activity of a separate plasma-membrane bound target protein
are seven -pass transmembrane proteins |
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Term
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Definition
| heterotrimeric GTP-binding protein |
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Term
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Definition
| the enzymatic linkage of saccharides to proteins lipids or other organic molecules |
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Term
| RGS: Regulator of G-protein signaling |
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Definition
| proteins that bind Galpha subunits vias 120aa "RGS-box" domain, catalyzing GTPase activity |
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Term
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Definition
| GTPase-accelerating proteins. enhance the Galpha subunits intrinsic rate of GTP hydrolysis |
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Term
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Definition
| Guanine nucleotide Exchange Factors. facilitate release of GDP from Galpha subunits, subsequent binding of GTP and release of Gbeta-gamma |
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Term
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Definition
| RGS, G-protein coupled receptor. Pigment in eye responsible for photoreceptor cells |
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Term
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Definition
| highly conserved triplet of amino acids located in the intracellular loop of the 7TM that is key in signal transduction |
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Term
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Definition
| enzyme that hydrolyzes phospholipids |
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Term
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Definition
| role in signal transduction as a second messenger by releasing inositol triphosphate |
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Term
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Definition
| cyclic adenosine monophosphate; second messenger in signal transduction |
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