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fungi lecture 1 Intro to Mycology
basic structure of fungi and basic mycoses superficial cutaneous subcutaneous
28
Medical
Graduate
04/13/2011

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Term
Yeast
Definition
unicellular growth form of fungi; budding
Term
blastoconidia
Definition
the budding part (in yeast reproduction)
Term
pseudohyphae
Definition
an exaggerated form of budding (in yeast reproduction)
Term
molds
Definition
hyphal growth form of fungi (not pseudohyphae which are yeast), characterized by apical elongation at its end

mold=elongating
yeast=budding
Term
mycelium
Definition
mass of hyphae
Term
in dimorphic fungi, the mold form generally grows better at ____ temp, and the yeast form grows at temperatures closer to _____ temp
Definition
room(25C), body (37C)
Term
aerial hyphae
Definition
grow upward and release spores
Term
chitin
Definition
a major component of cell wall, a N-acetylgucosamine monopolymer, and a target for anti-fungal drugs
Term
ergosterol
Definition
a unique target for fungal antibiotics in the plasma membrane
Term
T or F
There is no difference between most mammalian eukaryotic cells and fungi
Definition
False, in fungi the nuclear membrane doens't disappear during division; for other 'higher' eukaryotes it does disappear during division
Term
saprophytes
Definition
obtain carbon cmpds from non-living organic substrates; (parasites obtain carbon from living hosts)
Term
Fungi release enzymes for extracellular digestion. Then they absorb broken-down materials such as simple sugars and ___________
Definition
amino acids
Term
why don't fungi just engulf stuff?
Definition
they have a rigid cell wall with chitin
Term
at the apical end of a mold (hyphae), you find vacuoles which have a balance of the enzymes: _____________ and _______________, which are necessary for elongation
Definition
chitin synthetase and chitinase
Term
allergies are one type of fungal disease; allergies happen when exposed to fungal ___________
Definition
spores
Term
poisonous mushroom toxins that aren't killed by heat often target RNA synthesis in this organ
Definition
what is the liver
Term
improper wet storage of grains and peanuts produces these potential carcinogen-toxins that binds DNA
Definition
what are aflatoxins (Asperigillus flavus)
Term
mycoses that promotes no cellular immune response
Definition
what is superficial mycoses
Term
pityriasis versicolor
cause
diagnosis
treatment
Definition
a superficial mycoses caused by malassezia furfur

diagnosis made by observing fungal elements on areas of the body rich in sebacceous glands (hair)

easily treated with topical azoles
Term
tinea nigra
Definition
superficial mycoses caused by hortaea werneckii
dark color on hands or soles of feet
Term
T or F
black and white piedra colozine the follicle
Definition
F
white and black piedra are on the shaft of the hair
easily treated by shampooing
Term
what are the genuses of fungi that cause cutaneous mycoses
Definition
the dermatophytes--trichophyton, microsporum, and epidermophyton
Term
what are some common clinical manifestations of cutaneous mycoses
Definition
tinae pedis (athletes foot)
tinae cruris (jock itch)
tinae barbae (beard)
tinae capitis (head)
tinae corporus (body, looks like ring worm expanding)
onychomycosis, on the nails, not easily treated
Term
kerion
Definition
site of hair loss; fungi are easily transmitted from pets to humans
Term
cutaneous mycoses such as __________ can be scraped off of one's body, and treated with ________ to be seen in the lab
Definition
tinae corporis, KOH
Term
nodular, ulcerative lesions along the lymphatics are caused by this subcutaneous infectious fungii
Definition
the disease is called lymphocutaneous sporotrichosis; it is caused by sporothrix schenkii; it has been associated with foresters planting seedlings, occupational
Term
chromoblastomycosis is a _____________ mycoses; lesions look like ________________; can take years to appear after infection; extreme cases occured after people walked through thorny bushes and vegetation without protective __________
Definition
subcutaneous, warty-cauliflower; foot-wear or clothing
Term
Subcutaneous Zygomycosis
key terms
Definition
masses
traumatic implantation of the fungus
localized to the shoulder, pelvis, hips,and thighs
associated with tropical plants
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