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fungi cleanup
fungi cleanup
23
Agriculture
Pre-School
04/30/2011

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Term
asexual, sexual reproduction
Definition
characterizes anamorphic state of a fungus, characterizes teleomorphic state of a fungus
Term
Coccidioides (resistance to phagocytosis)
Definition
extracellular protease production
Term
5-Fluorocytosine (5FC)
Acts as cytosine antagonist and inhibits nucleic acid synthesis (mostly RNA).
Definition
Resistance development common for many fungi, May cause bone marrow suppression
Term
polyenes (ampB)
Definition
Amphipathic macrolides that bind to ergosterol in fungal cell membranes.
2. Disruption of membrane permeability leads to cell death.
Term
amphotericin B,
Definition
severe toxicity to the host, lipid is less toxic
Term
Azoles
Definition
Prevent ergosterol synthesis via inhibition of cytochrome p450 enzymes causing disruption of membrane integrity
Term
"first generation" azoles
Definition
micon, clotrim...keto
Term
Echinocandins (...fungin)
Definition
lipopeptides that inhibit synthesis of beta-(1-3)-D-glucan,
essential component of fungal cell walls.
candida
Term
Terbinafine (lamisil)
Definition
allylamine derivative that inhibits squalene epoxidase, essential enzyme for ergosterol synthesis
Term
Candida, Aspergillus and Cryptococcus
Definition
FDA-cleared tests now available for detecting cellular antigens of ????
Term
itraconazole,sski (lymphocutaneous)
Definition
sporothrix drug
Term
tinea capitis, endothrix, tirchophyta
Definition
black dot
Term
chromomycetes
Definition
many genera described but most common agents include Fonsecaea spp., Cladosporium spp., Exophiala spp., Wangiella spp., and Phialophora spp
Term
dimorphic (endemic, uncommon)
Definition
endemic vs nonendemic...common vs uncommon
Term
microcondia
Definition
infective (micro or macro usually?)
Term
histoplasma
Definition
exoantigen test
Term
cryptococcus
Definition
urease production
Term
zygomycetes
Definition
broad non septate hyphae
Term
rhizopus
Definition
RAM (which - GRAY-WHITE), others white then gray
Term
candida
Definition
differentiated squamous cell carcinoma of the cervix, budding yeast.
antibiotics, hospitalization
Term
histoplasma
Definition

right upper lobe lung mass, fever to 38.9oC and a cough productive of white sputum that was slightly bloody, cytological examination for cancer was negative

"granuloma formation"

Term
tinea versicolor
Definition
ooff ssccaallyy wwhhiittee ppaattcchhyy lleessiioonnss oonn hhiiss nneecckk aanndd bbaacckk. ((iittcchhyy)) bbuutt tthheerree iiss nnoo ppaaiin
Term
zygomycetes
Definition
with fever, left eye swelling, ptosis, and left frontal headache.broad, aseptate hyphae
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