Term
What are the non-selective alpha blockers?
What are the uses and adverse effects?
Which has irreversible block?
Which has histamine and anticholinergic properties?
Which is given IV with short Half life? |
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Definition
Phentolamine: ER HPTN, Antichol+Hist, IV w/ short half-life
Phenoxybenzamine: Pheochromocytoma, Irreversible
Adverse: Othostatic Hypo and Reflex tach |
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Term
What are the selective alpha adrenergic bockers
Which are used for BPH, which is prostate specific?
Which cause syncopy?
Which decreases LDL, and raises HDL? |
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Definition
Prazosin-Raises HDL/lowers LDL, Syncopy,
Terazosin/Doxasin-BPH
Tamsulosin-BPH, Prostate specific |
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Term
What is the mechanism of Reserpin?
What is it used for?
What are the adverse effects? |
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Definition
Norepinephrine depletion
Use: HPTN
Adverse: Depression and Suicide |
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Term
What is the mechanism of Guandrel and Guanethidine?
What is the limitation to its use? |
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Definition
False neurotransmitter uptaken in norepi vesicles
Limit: Tolerance
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Term
What is the mechanism of Metyrosine?
What is the limitation to its use? |
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Definition
Generates Methylate false neurotransmitters
Limit: Tolerance |
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