| Term 
 
        | ________ is effective against broad spectrum fungi |  | Definition 
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        | Term 
 | Definition 
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        | Term 
 
        | What are the two adverse effects of Itraconazole usage? |  | Definition 
 
        | Cardiosuppression and liver damage |  | 
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        | Term 
 
        | Itraconazole inhibits______, which can ____ drugs levels |  | Definition 
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        | Term 
 
        | Itraconazole's absorption can be reduced by |  | Definition 
 
        | drugs that reduce gastric aciidity |  | 
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        | Term 
 
        | List two classes of drugs that may reduce gastric acidity? |  | Definition 
 
        | H2 antagonists and proton pump inhibitors |  | 
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        | Term 
 
        | In __________, there is a blockage of __________outflow. |  | Definition 
 
        | angle-closure glacoma and aqueous humor *this causes a rise in IOP
 |  | 
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        | Term 
 
        | If angle-closure glaucoma is not treated, then ___________ to optic nerve occurs in_______ |  | Definition 
 
        | irreversible damage and 1-2days |  | 
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        | Term 
 
        | What is the major risk factor for open-angle glaucoma? |  | Definition 
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        | Term 
 
        | How is drug therapy directed for open-angle glaucoma? |  | Definition 
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        | Term 
 
        | ________ is treated with drugs to reduce IOP and surgery |  | Definition 
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        | Term 
 | Definition 
 
        | facilitating aqueous humor outflow or reducing its production |  | 
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        | Term 
 
        | List the three drug families which are first line tx for open angle-glaucoma. |  | Definition 
 
        | beta blockers, alpha2-adrenergic agonists, and prostaglandins |  | 
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        | Term 
 
        | _________ decreases IOP by decreasing ________ |  | Definition 
 
        | Timolol and aqueous humor production |  | 
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        | Term 
 
        | Topical beta blockers  can cause_______, _______, and _______. |  | Definition 
 
        | bronchospasm, bradycaria, and AV heart block |  | 
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        | Term 
 
        | __________ may cause browning of the iris and increased pigmentation of the skin around the eyes. |  | Definition 
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        | Term 
 
        | What drugs paralyze the ciliary muscle? |  | Definition 
 | 
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        | Term 
 
        | Mydriatics _________ the pupil. |  | Definition 
 | 
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        | Term 
 
        | Atropine and other anticholinergic drugs cause________ and__________ |  | Definition 
 
        | cycloplegia (ciliary muscle paralysis) and mydriasis (pupil dilation) |  | 
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        | Term 
 
        | How does Atropine cause cycloplegia? |  | Definition 
 
        | blocks muscarinic receptors on the ciliary muscle |  | 
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        | Term 
 
        | How does atropine cause mydriasis? |  | Definition 
 
        | blocks muscarinic receptors on the iris sphincter |  | 
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        | Term 
 
        | Paralyzing the ciliary muscle with anticholinergic drugs prevents |  | Definition 
 | 
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        | Term 
 
        | Paralyzing the iris sphincter with anticholinergic drugs causes |  | Definition 
 
        | photophobia (the pupils do not constrict to light) |  | 
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        | Term 
 
        | _________ is an adrenergic agonist. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Phenylephrine causes________ by stimulating___________receptors on the radial muscle of the eye. |  | Definition 
 
        | mydriasis and alpha-adrenergic |  | 
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        | Term 
 
        | ______________ take several weeks to decrease allergy symptoms in eyes |  | Definition 
 
        | Ocular mast cell stabilizers *usu not rx'd bc of this reason
 |  | 
        |  | 
        
        | Term 
 
        | Corticosteroid drops (for eyes) decrease inflammation but may |  | Definition 
 
        | mask an infection *APNs should avoid prescribing these
 |  | 
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        | Term 
 
        | ________ can be used for drys eyes and there are _______ with regular or frequent usage. |  | Definition 
 
        | Artificial tears and zero risk |  | 
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        | Term 
 
        | Topical glucocorticoids relieve________ and _________ associated with dermatologic disorders. |  | Definition 
 | 
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        | Term 
 
        | What are the four groups of potency classified for glucocorticoids? |  | Definition 
 
        | low, medium, high, and super-high |  | 
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        | Term 
 
        | What are the risk of prolonged usage of topical glucorticoids? |  | Definition 
 
        | atrophy of the dermis and epidermis |  | 
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        | Term 
 
        | Topical glucorticoids can cause |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Growth retardation and adrenal suppression are side effects of |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What promotes shedding of the horny layer of the skin? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | salicylic acid, sulfur, and benzoyl peroxide |  | 
        |  | 
        
        | Term 
 
        | List three topical antibiotics that tx acne. |  | Definition 
 
        | benzoyl peroxide, clindamycin, and erythromycin |  | 
        |  | 
        
        | Term 
 
        | How does benzoyl peroxide, clindamycin, and erythromycin work to clear up acne? |  | Definition 
 
        | suppresses the growth of propionibacterium acnes |  | 
        |  | 
        
        | Term 
 
        | Tretinoin, adapalene, and tazarotene are all |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Tretinoin, adapalene, and tazarotene clear acne by normalizing__________ of epitheial cells in______. |  | Definition 
 
        | hyperproliferation and hair follicles |  | 
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        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | Name a drug reserved for severe acne. |  | Definition 
 | 
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        | Term 
 
        | Nosebleeds, inflammation of the lip and eyes, pain and stiffness of muscle, bones, and joints are all side effects of |  | Definition 
 | 
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        | Term 
 | Definition 
 | 
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        | Term 
 
        | Frequency of the application of _____ reduces the risk of sunburn. |  | Definition 
 | 
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        | Term 
 
        | Topical immunosuppressants work against the _________ process of atopic dermatitis. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Topical immunosuppressants are not_________ |  | Definition 
 | 
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        | Term 
 
        | There exist some rare association of cancer in children who have used |  | Definition 
 
        | topical immunosuppressants |  | 
        |  | 
        
        | Term 
 
        | Children with antibiotic resistant AOM, the tx of choice |  | Definition 
 
        | augmentin Es-600 (amoxicillin/clavulanate) |  | 
        |  | 
        
        | Term 
 
        | Vaccinating against the flu virus or strept pneumoniae (prevnar) can reduce the risk of |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Otitis media with effussion (OME) is _________ in the middle ear without________ |  | Definition 
 
        | fluid and local or systemic illness |  | 
        |  | 
        
        | Term 
 
        | OME may cause ______ but not________. |  | Definition 
 
        | mild hearing loss and pain |  | 
        |  | 
        
        | Term 
 
        | OME is seen in children following |  | Definition 
 | 
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        | Term 
 | Definition 
 | 
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        | Term 
 
        | Antibiotics should not be used with____ bc it has minimal effect. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Otitis externa is inflammation of the |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is another name for otitis externa? |  | Definition 
 
        | swimmer's ear *which is a bacterial infection of the EAC
 |  | 
        |  | 
        
        | Term 
 
        | In most cases, acute otitis externa can be tx |  | Definition 
 
        | cleaning and use of ear drops |  | 
        |  | 
        
        | Term 
 
        | Ears drops to clean/tx acute OE may contain |  | Definition 
 
        | alcohol, 2%acetic acid, hydrocortisone, or an antibacterial drug. |  | 
        |  | 
        
        | Term 
 
        | Ear drops to treat OE may include |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Preferred antibiotics drops for OE are |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | The concentration of otic drops are ______ than oral medications |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | _________ is a good choice of treatment for adults with OE. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | ________ is rare but a potentially fatal complication of acute OE |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | This condition occurs when bacteria in the EAC invaed the mastoid or temporal bone. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the name of the organism responsible for Necrotizing OE? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | How do you manage Necrotizing OE? |  | Definition 
 
        | cleansing and use of antipseudomonal drugs |  | 
        |  | 
        
        | Term 
 
        | All pts with necrotizing OE should receive antipseudomonal drugs such as |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Pt with mild cases of necrotizing OE should receive |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Pt with severe cases of necrotizing OE  should receive |  | Definition 
 
        | IV therapy -imipenem/cilastatin (primaxin)
 |  | 
        |  | 
        
        | Term 
 
        | The most common fungal pathogen for OE is |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | In 10% of OE cases, the infection is due to |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Fungal OE can be managed by ______ and ________ |  | Definition 
 
        | cleansing and acidifying drops -2% acetic acid solution
 |  | 
        |  | 
        
        | Term 
 
        | Topical solutions can be used to fungal OE as well. Name one. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | If fungal OE is unresponsive to typical treatment, then ______ drugs can be initiated. |  | Definition 
 
        | oral -itraconazole and fluconazole
 |  | 
        |  |