Term
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Definition
-act primarily as coenzymes
-Work as catalysts
-energy-producing metabolic reactions |
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Term
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Definition
Riboflavin: coenzyme in energy metabolism
-accepts & donates e- as FAD/FADH2 |
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Term
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Definition
Niacin: nicotinic acid
-coenzyme in energy metabolism
- ~200 require NAD & NADP
- supports fatty acid synthesis as NADPH |
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Term
| Niacin Deficiency Disease |
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Definition
Pellagra
-Associated w/ the 4 Ds: dermatitis, dementia, diarrhea, and death
High doses used to treat hbc:
Reduces serum cholesterol, triglycerides, and LDL, raises HDL
- side effects: liver damage & skin flushing |
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Term
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Definition
Pantothenic acid is a component of acetyl CoA
-pantothenic acid helps form acetyl CoA from pyruvate. |
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Term
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Definition
- Coenzyme for pyruvate carboxylase
- Coenzyme for acetyl CoA carboxylase, initiates fatty acid synthesis
- Affects gene expression of more than 2,000 genes |
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Term
| Vitamin B6 Active Coenzyme Form |
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Definition
| PLP: coenzyme in liver that transfers NH2-, COO-, COOH |
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Term
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Definition
Deficiency in folate and B12
Red blood cells get really big |
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Term
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Definition
Elevated levels: increase the rish of heart disease
Forming cysteine methionine from homo can lower homo levels & reduce risk of heart disease |
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Term
| Folate and Methylation Reactions |
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Definition
| Vitamin B12 helps transfer a methyl group (–CH3) from the folate coenzyme THFA |
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Term
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Definition
- Needed for collagen synthesis
- Antioxidant
- Improves iron absorption
- Synthesis of vital cell components
- Immune function |
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