Term
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Definition
anti-arrhythmic
oral hypoglycemic agents |
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Term
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Definition
vascular (arterial) relaxation
promotion of hair growth |
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Term
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Definition
VW class III and non-selective beta-blocker
ventricular and supra ventricular arrhythmias
torsades de pointes |
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Term
| Amiodarone, class? use? SEs |
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Definition
Class X (mixture of class I-IV)
anti-arrhythmic (most efficacious)
MANY side effects (thyroid, neurologic, opthalmic, etc) and long half-life, PK favors toxicit |
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Term
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Definition
VW class X, anti-arrhythmic
Less toxic Amiodarone, shorter T1/2 |
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Term
| Sulfonyl-urea agents; action? SEs? examples? |
|
Definition
hypoglycemic agents
pancreatic K-channel blockers -> increased inslulin release
0rally administered
can't use in Type I DM
all have "gl" in name
SEs - increased wight and decreased GLU
glibenclamid, glyburide, glipizid, glimepririd |
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Term
| Metformin, use? action? byproduct? |
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Definition
Non-Sulfonyl-urea hypoglycemic agent (don't know how it works)
One of the best drugs for diabetes control
Inhibits lactate uptake and hepatic GNG via AMP-kinase
Byproduct - guanidine |
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Term
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Definition
Non-Sulfonyl-urea insulin release
end in "-glinid"
Rapid onset, short action
less hypoglycemia and weight gain than SUs |
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Term
| Nicorandil, action? use?, SEs? |
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Definition
K-channel opener
arterial relaxation (decreased afterload) also stimulates cGMP -> relax venous smooth muscle (decreased preload)
tx of angina, congestive heart failure, HTN
SEs - oral ulcerations |
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Term
|
Definition
K-channel opener
dilate arteries -> increased 02 and nutrient supply -> hair growth! |
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