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First Semester/Mini 1 part 1
Regulation of Cell Volumn
11
Physiology
Graduate
12/07/2010

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Cards

Term
What is the Total body of water?
Definition

Total B(60%)=ICFV(40%) + ECFV(20%)

**ECFV

    - interstitial fluid volume (15%)-10.5L

    - plasma volume (5%) - 3.5

TB = 42L

ICFV = 28L

ECFV = 14 L

 

Term
Osmosis
Definition
net diffusion of water from high to low concentration
Term
Osmole
Definition

measure of the total # of particles

- when calculating the osmole, make sure you multiply mole & # of ions

Term
Osmolarity
Definition
osmoles per kilogram of solution
Term
Osmolality
Definition
osmoles per kilogram of water
Term
Osmotic Pressure
Definition

pressure necessary to stop the net movement of water

- pressure is equal and opposite 

- Van't Hoff Equation

- Gibbs-Donnan Effect

  * Proteins attract small diffusible cations maintaining neutrality

* Cells utilize the Na/K ATPase to keep the system balance w/o diffusing water

        * Osmotic effect is know as colloid osmotic pressure or plasma oncotic pressure

Term
Tonicity
Definition

- Determined by the concent. of only those particles that are impermeable to the cell membrane (saline)

- Osmolal concent. of extracellular fluid compared to intracellular fluid

- isotonic, hypertonic, hypotonic

Term
Osmotic
Definition

- Solution of molecules freely permeable to the plasma membrane

- isosmotic, hyposmotic, hyperosmotic 

Term
Blood Volume 
Definition

 = plasma volume + RBCV

 

 = plasma volume / 1-hematocrit

 

Hematocrit (Hct) = RBCV / blood volume

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