Term
| Anticentromere antibodies |
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Definition
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Term
| Antidesmoglein (epithelial) antibodies |
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Definition
| Pemphigus vulgaris (blistering) |
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Term
| Anti-glomerular basement membrane antibodies |
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Definition
| Goodpasture's syndrome (glomerulonephritis and lung hemorrhage) |
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Term
|
Definition
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Term
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Definition
| Rheumatoid arthritis (systemic inflammation, joint pannus, boutonniere deformity) |
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Term
| Antimitochondrial antibodies (AMAs) |
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Definition
| Primary biliary cirrhosis (female, cholestasis, portal hypertension) |
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Term
| Antineutrophil cystoplasmic antibodies (ANCAs) |
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Definition
| Vasculitis (Wegener's [c-ANCA), microscopic polyangitis/Churg-Strauss [p-ANCA], glomerulonephritis [pauci-immune]) |
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Term
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Definition
| Idiopathy thrombocytopenic purpura (ITP) (bleeding diathesis) |
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Term
| Anti-topoisomerase antibodies |
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Definition
| Diffuse systemic scleroderma |
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Term
| Anti-transglutaminase/antigliadin antibodies |
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Definition
| Celiac disease (diarrhea, distention, weight loss) |
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Term
| Azurophilic granular needles in leukemic blasts |
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Definition
| Auer rods (acute myelogenous leukemia: especially the promyelocytic type) |
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Term
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Definition
| Ankylosing spondylitis (chronic inflammatory arthritis: B27) |
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Term
| Basophilic nuclear remnants in RBCs |
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Definition
| Howell-Jolly bodies (due to splenectomy or nonfunctional spleen) |
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Term
| Basophilic stippling of RBCs |
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Definition
| Lead poisoning or sideroblastic anemia |
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Term
|
Definition
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|
Term
| "Boot-shaped" heart on x-ray |
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Definition
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Term
| Branching gram-positive rods with sulfur granules |
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Definition
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Term
| Bronchogenic apical lung tumor |
|
Definition
| Pancoast's tumor (can compress sympathetic ganglion and cause Horner's syndrome) |
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Term
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Definition
Hemorrhage (hemosiderin) causes brown color of osteolytic cysts. Due to:
- Hyperparathyroidism
- Osteitis fibrosa cystica (von Recklinghausen's disease of bone)
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|
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Term
| Cardiomegaly with apical atrophy |
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Definition
| Chagas' disease (Trypanosoma cruzi) |
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Term
| Cellular crescents in Bowman's capsule |
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Definition
| Rapidly progressive crescentic glomerulonephritis |
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Term
| "Chocolate cyst" of ovary |
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Definition
| Endometriosis (frequently involves both ovaries) |
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|
Term
| Circular grouping of dark tumor cells surrounding pale neurofibrils |
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Definition
| Homer Wright rosettes ([adrenal] neuroblastoma, medulloblastoma, [Ewing sarcoma]) |
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Term
| Colonies of mucoid Psuedomonas in lungs |
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Definition
| Cystic fibrosis (CFTR mutation in Caucasians resulting in fat-soluble vitamin deficiency and mucous plugs) |
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Term
| Degeneration of dorsal column nerves |
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Definition
| Tabes dorsalis (tertiary syphili) [positive Romberg] |
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Term
| Depigmentation of neurons in substantia nigra |
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Definition
| Parkinson's disease (basal ganglia disorder: rigidity, resting tremor, bradykinesia) |
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Term
| Desquamated epithelium casts in sputum |
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Definition
| Curschmann's spirals (bronchial asthma; can result in whorled mucous plugs) |
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Term
| Disarray granulosa cells in eosinophilic fluid |
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Definition
| Call-Exner bodies (granulosa-theca cell tumor of the ovary) |
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Term
| Dysplastic squamous cervical cells with nuclear enlargment and hyperchromasia |
|
Definition
Koilocytes (HPV: predisposes to cervical cancer)
[Perinuclear cytoplasmic clearing] |
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|
Term
| Enlarged cells with intranuclear inclusion bodies |
|
Definition
| "Owl's eye" appearance of CMV [Cowdry type A] |
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|
Term
| Enlarged thyroid cells with ground glass nuclei |
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Definition
| "Orphan Annie" eye nuclei (papillary carcinoma of the thyroid) |
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|
Term
| Eosinophilic cytoplasmic inclusion in liver cell |
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Definition
| Mallory bodies (alcoholic liver disease) |
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|
Term
| Eosinophilic cytoplasmic inclusion in nerve cell |
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Definition
| Lewy body (Parkinson's disease) |
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|
Term
| Eosinophilic globule in liver |
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Definition
| Councilman body (toxic or viral hepatitis, often yellow fever) |
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|
Term
| Eosinophilic inclusion bodies in cytoplasm of hippocampal nerve cells |
|
Definition
Rabies virus (Lyssavirus)
[Negri bodies] |
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|
Term
| Extracellular amyloid deposition in gray matter of brain |
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Definition
| Senile plaques (Alzheimer's disease) |
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|
Term
| Giant B cells with bilobed nuclei with prominent inclusions ("owl's eye") |
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Definition
| Reed-Sternberg cells (Hodgkin's lymphoma) |
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|
Term
| Glomerulus-like structure surrounding vessel in germ cells |
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Definition
| Schiller-Duval bodies (yolk sac tumor) |
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Term
| "Hair-on-end" (crew-cut) appearance on x-ray |
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Definition
| ß-thalassemia, sickle cell anemia (extramedullary hematopoiesis) |
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Term
|
Definition
| Choriocarcinoma, hyaditidiform mole (occurs with and without embryo) |
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|
Term
| Heart nodules (inflammatory) |
|
Definition
Aschoff bodies (rheumatic fever)
[Focal myocardial inflammation with multinuclear giant cells] |
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|
Term
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Definition
Infectious mononucleosis (EBV)
[Antibodies = IgM] |
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|
Term
| Hexagonal, double-pointed, needle-like crystals in bronchial secretions |
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Definition
| Bronchial asthma (Charcot-Leyden crystals: eosinophilic granules) |
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Term
|
Definition
DVT, pulmonary embolism, DIC
[Budd-Chiari] |
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Term
| "Honeycomb lung" on x-ray |
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Definition
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|
Term
| Hypersegmented neutrophils |
|
Definition
| Megaloblastic anemia (B12, folate deficiency) |
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Term
| Hypochromic, microcytic anemia |
|
Definition
Iron deficiency anemia, lead poisoning, thalassemia (HbF somtimes present)
[Anemia of chronic disease] |
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