primary adrenocortical deficiency

Low BP

Hyponatremia

Hyperkalemia

Polyostotic fibrous dysplasia

precocious puberty

cafe-au-lait spots

short stature

young girls

Guillain-Barre

(increased protein in CSF with only modest increase in cell count)

SLE

Antimitochondria antibodies

Vasculitis

(ANCAs)

Neurosyphilis

(reactive to accomodation but NOT to light)

sickle cell anemia

in popliteal fossa

Rheumatoid arthritis

Hyperreninemia

genetic defect in thick ascending limp of loop of Henle

defective dystrophin

less sever than Duchenne's MD

Multiple myeloma (kappa or lambda Ig light chains in urin)

OR

Waldenstrom's macroglobulinemia (IgM)

Tetralogy of Fallot

OR

Right ventricular hypertrophy

Hemorrhage causes brown color of osteolytic cysts

due to:

- hyperparathyroidism

- Osteitis fibrosa cystic (von Recklinghausen's dx)

X-linked agammaglobulinemia

inability to generate mature B-cells

- present in childhood w/ recurrent infections w/ extracellular encapsulated bacteria

Burkitt's lymphoma

8;14 translocation

associated w/ EBV

Wegener's granulomatosis

Polyarteritis nodosa

Gas emboli

Mycosis fungoides

(cutaneous T-cell lymphoma)

Haemophilus ducreyi (painful)

Multiple sclerosis -->

nystagmus, intention tremor, scanning speech

Cholangitis -->

jaundice, RUQ pain, fever

- Tay-Sachs

- Niemann-Pick

- Central retinal artery occlusion

Central apnea in CHF

and

increased intracranial pressure

Endometriosis

(frequently involves ovaries)

facial muscle spasm upon tapping

due to Hypocalcemia

Mycoplasma pneumoniae

or

Infectious mononucleosis

in retina, indicate neuronal ischemia

due to chronic hypertension

Measles  

(Coryza = nasal congestion)

Congenital unconjugated hyperbilirubinemia

(UDP-glucuronosyltransferase deficiency)

whorled mucous plugs

(broncial asthma)

D-dimers

Parkinson's disease

(a basal ganglia disorder)

Granuloma inguinale

Congenital conjugated hyperbilirubinemia (black liver)

Autosomal Recessive

Deletion of dystrophin gene (Xp21)

X-linked recessive

Osteoarthritis

- polished, ivory like appearance of bone

Trisomy 18

- associated w/ rocker-bottom fee, low set ears, heart disease

Late cyanosis shunt

(uncorrected L --> R shunt becomes R --> L)

defect in collagen synthesis

results in elastic skin

Superior trunk brachial plexus injury

("waiter's tip")

Acute cholecystitis

Gaucher's disease

Lysosomal storage disease

Glucocerebrosidase deficiency

Ghon focus

Use of pts arms to help pick self off the floor

- associated with Duchenne's MD

Extramedullary hematopoiesis

due to: 

- β-thalassemia

- Sickel cell anemia

hCG elevated

Choriocarcinoma

OR

Hydatidiform mole

(or pregnancy)

Osteoarthritis

DIP swelling secondary to osteophytes

High-output cardiac failure

(dilated cardiomyopathy)

Wet beriberi

(thiamine, vitamin B1 deficiency)

Reiter's syndrome

or

Ankylosing spondylitis

Diabetes melitus type 1

(caused by autoimmune destruction of β cells)

Iron deficiency anemia

lead poisoning

Anencephaly

Spina bifida cystica

Gout

Lesch-Nyhan syndrome

Myeloproliferative disorders

Loop and thiazide diuretics

Jarisch-Herxheimer reaction

Margan's syndrome

(fibrilin deficit)

Lisch nodules

- Multiple myeloma (M protein, IgG or IgA)

- Monoclonal gammopathy of undetermined significance

- Waldenströms macroglobulinemia (M protein, IgM)

Wegener's granulomatosis

Goodpasture's disease (hemoptysis and renal disease)

Sphingomyelinase deficiency

bcr-abl

CML (sometimes associated AML)

Emphysema

- centroacinar --> smoking

- panacinar --> α-1 antitrypsin deficiency

Podadra

Minimal change disease

Guillain-Barre syndrome

(ascending paralysis)

Lysosomal glucosidase deficiency

associated with cardiomegaly

Secondary syphilis

RMSF

Pseudogout

Calcium pyrophosphate crystals

Endocarditis

(spots in eyes)

(RBCs stacked up like coins)

Multiple myeloma

Left to Right shunt (VSD, ASD, PDA)

Mitral regurg

LV failure (CHF)

Simian crease

Erythema infectiosim (5th disease)

parvovirus B19

Soap bubble on x-ray

Scarlet fever

Philidelphia chromosome

CML (bcr-abl hybrid)

M3 type of AML

responsive to all-trans retinoic acid

Epiglottitis (H. influenza)

von Recklinghausen's disease

von Recklinghausen's disease of bone

Osteitis fibrosa cystica

("brown tumor of bone")

Waxy cast

Acute pyelonephritis

Wermer's syndrome

Primary amyloidosis

(Ig light chains --> multiple myeloma)

AA protein

Secondary

(serum amyloid-associated protein --> chronic inflammatory disease)

Transthyretin

Senile cardiac amyloidosis

(AF)

Diabetes mellitus type 2

(AE)

A-CAL protein

Alzheimer's disease amyloidosis

(ß-amyloid)

Dialysis associated amyloidosis

(MHC class I protein)