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First Aid - Equation Review
USMLE Step 1 First Aid - Equation Review
26
Medical
Professional
12/29/2011
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Term
Sensitivity
 Definition
Sensitivity = TP / (TP + FN)
Term
Specificity
 Definition
Specificity = TN / (TN + FP)
Term
PPV
 Definition
PPV = TP / (TP + FP)
Term
NPV
 Definition
NPV = TN / (TN +FN)
Term
Relative Risk
 Definition
R = [a/a+b] /  [c/c+d]
Term
Attributable Risk
 Definition
AR = [a/a+b] - [c/c+d]
Term
Hardy-Weinberg equilibrium
 Definition

p2 + 2pq + q2

 

p + q = 1
Term
Henderson Hasselbalch equation
 Definition
pH = pKa + log ( [HCO3-] / 0.03xPCO2 )
Term
Volume of Distribution (Vd)
 Definition
Vd = amount of drug in the body / plasma drug concentration
Term
Clearance
 Definition
CL = rate of elimination of drug / plasma drug concentration
Term
Half Life
 Definition
t1/2 = (0.7 x Vd) / CL 
Term
Loading Dose
 Definition
LD = Cp x (Vd/F)
Term
Maintenance dose 
 Definition
MD = Cp x (CL/F)
Term
Cardiac Output
 Definition
CO = rate of O2 consumption / (arterial O2 content - venous O2 content)
Term
Cardiac Output
 Definition
CO = SV x HR
Term
Mean arterial pressure
 Definition

MAP = CO x TPR

 

MAP = 1/3 systolic + 2/3 diastolic
Term
Stroke Volume
 Definition
SV = EDV - ESV
Term
Ejection Fraction
 Definition
EF = (SV / EDV) x 100
Term
Resistance
 Definition
R = driving pressure / flow = 8η(viscosity) x length / ∏r4
Term
Net Filtration Pressure
 Definition
Pnet = [(Pc - Pi) - (∏c - ∏i)] 
Term
Glomerular Filtration Rate
 Definition
GFR = Uinulin x (V/Pinulin) = Cinulin
Term
Glomerular Filtration Rate 
 Definition
GFR = Kf [(PGC-PBS) - (∏GC-∏BS)]
Term
Effective Renal Plasma Flow
 Definition
ERPF = UPAH x (V/PAH) = CPAH
Term
Renal Blood flow
 Definition
RBF = RPF / 1-HCT
Term
Filtration fraction
 Definition
FF = GFR/RPF
Term
Physiologic Dead Space
 Definition
VD = VT x ((PaCO2 - PeCO2) / PaCO2) 
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