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Final Exam: Section 1
Hypothalamus
43
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Undergraduate 3
12/15/2015

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Term
The major function of the hypothalamus is to coordinate _____, _____, & ______ activities to maintain homeostasis & fulfill bodily needs
Definition
autonomic, endocrine, & somatic motor
Term
The optic chiasm marks the anterior or ______ region
Definition
chiasmatic
Term
The infundibulum marks the middle or ______ region
Definition
tuberal
Term
The mammillary body marks the posterior or ______ region
Definition
mammillary
Term
The hypothalamus can be divided into 3 major subdivisions in the mediolateral dimension: ______ nucleus along the third ventricle, ______ (middle) zone, & _____ area
Definition
periventricular nucleus, medial zone, lateral hypothalamic area
Term
The lateral hypothalamic area lies lateral to the _____ & has diffusely organized cells penetrated by thinly myelinated & unmyelinated axons in the diffusely distributed medial forebrain bundle (MFB)
Definition
fornix
Term
Major afferents to the hypothalamus arise from the brainstem reticular formation (via the ______)
Definition
dorsal longitudinal fasciculus
Term
Relatively unprocessed ______ information reaches the hypothalamus
Definition
sensory information
Term
The hypothalamus receives highly processed sensory information relating to ______ & ______ events
Definition
emotionally significant & memorable
Term
The hypothalamus responds directly or indirectly to circulating levels of _______ & physical events
Definition
non-neuronal substances
Term
With few exceptions, efferents from the hypothalamus ______ the afferents
Definition
reciprocate
Term
Many hypothalamic functions are carried out by ______ of mutually interconnected cells
Definition
extensive networks
Term
Stimulation within the ventromedial & lateral hypothalamus can elicit ______ in animals, either defensive without attack or predatory
Definition
rage reactions
Term
The hypothalamus coordinates the complex somatic & visceral motor responses that form ______
Definition
emotional expression
Term
An old view of feeding behavior was the ______ hypothesis
Definition
dual center hypothesis
Term
Lesions of the ventromedial hypothalamus lead to excessive eating (______), suggesting that the VMH might be a satiety center
Definition
hyperphagia
Term
Lesions of the lateral hypothalamic area give rise to ______ & suggest a hunger center
Definition
anorexia
Term
______ is a hormone released from the gut & adipose tissue that activates cells in the arcuate, VMH, & DMH
Definition
leptin
Term
Leptin signaling probably has more to do with ______ than with calories consumed in an individual meal
Definition
long-term nutritional status
Term
Both MCH & orexin knock-outs are associated with ______
Definition
hypophagia
Term
Factors act on ______ cells to either stimulate feeding via the LHA or inhibit it via the VMH
Definition
arcuate nucleus
Term
The anterior preoptic area has a role in _______ behavior
Definition
sexual
Term
The ______ is known to be 3-7 times larger in male than in female rats
Definition
sexually dimorphic nucleus of the preoptic area
Term
The interstitial nuclei of the anterior hypothalamus (INAH) show ______ dimorphism
Definition
sexual
Term
The INAH3 in postmortem brains is smaller in homosexual than in heterosexual men, suggesting a role for this region in ______
Definition
sexual orientation
Term
Hypothalamic nuclei, such as the suprachiasmatic nucleus, & forebrain areas like the bed nucleus of the stria terminalis differ in ______ individuals
Definition
transexual
Term
The pituitary is divided into an ______ portion & a ______ portion
Definition
anterior & posterior
Term
______ neurons in the supraoptic & paraventricular nuclei are the source of neuronal input to the pituitary gland
Definition
magnocellular
Term
The _____ is derived from the neural tube & contains the axonal nerve endings of hypothalamic cells
Definition
neurohypophysis
Term
Cells that convert neural to hormonal signals are called ______
Definition
neuroendocrine transducers
Term
_______ has clear actions in females, such as uterine contraction during birthing & the milk ejection reflex
Definition
oxytocin
Term
______ is named for its contraction of vascular smooth muscle & increased blood pressure
Definition
vassopressin
Term
Vasopressin regulates fluid balance & is also called ______
Definition
antidiuretic hormone (ADH)
Term
______ respond to changes in blood osmolarity & are expressed on cells in the supraoptic & paraventricular nuclei & on circumventricular organs outside the blood-brain barrier
Definition
osmoreceptors
Term
Hypothalamic neurons receive ascending projections from the brainstem related to ______
Definition
blood pressure
Term
______ acts on the kidney to increase water reabsorption
Definition
ADH
Term
Lesions of the posterior pituitary gland or pituitary stalk lead to ______ (a condition of polyuria in which the patient excretes large quantities of urine daily)
Definition
diabetes insipidus
Term
The ______ contains epithelial cells from the primitive gut
Definition
adenohypophysis
Term
Hypothalamic control of the anterior pituitary occurs via the ______
Definition
hypophyseal portal blood supply
Term
The _______ forms a capillary bed within the median eminence
Definition
superior hypophyseal artery
Term
_______ in the hypothalamus & other CNS regions sense changes in blood temperature
Definition
thermoreceptors
Term
Cells in the ____ respond to increased temperature to stimulate heat loss via peripheral vasodilation, sweating, & accelerated respiration
Definition
anterior hypothalamus
Term
Cells in the ______ respond to decreased temperature to stimulate heat production & conservation by peripheral vasoconstriction, increased heart rate, increased metabolism, & increased somatic motor activity
Definition
posterior hypothalamus
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