Shared Flashcard Set

Details

Final Exam
Board of Registry Study Guide: Chemistry
70
Chemistry
Graduate
04/20/2013

Additional Chemistry Flashcards

 


 

Cards

Term
Which two conditions can "physiologically" elevate serum alkaline phosphatase?
Definition
Growth, third trimester of pregnancy
Term
In the liver, bilirubin is converted to
Definition
Bilirubin diglucuronide
Term
Calculate the creatinine clearance
Definition
CrCl= [Ucrea]/[SerumCrea] x volume/ (hours x 60)

corrected for BSA: CrCl x 1.73/bsa =
Term
AST and ALT are both elevated in which of the following disesae
Definition
viral hepatitis
Term
Calcium concentration in the serum is regulated by
Definition
PTH
Term
Blood PCO2 may be measured by
Definition
calculation of blood pH and total CO2 concentration
Term
A stimulant that causes localized sweating for a sweat test is
Definition
pilocarpine nitrate
Term
In the sweat test, the sweating stimulant is introduced to the skin by application of
Definition
an electric current
Term
Most of the carbon dioxide present in the blood is in the form of
Definition
bicarbonate ion
Term
The degree to which the kidney concentrated the glomerular filtrate can be determined by
Definition
urine to serum osmalality ratio
Term
A physician suspects his patient has pancreatitis, which tests would be most indicative of this disease?
Definition
amylase
Term
Lab results consistent with Respiratory acidosis
Definition
decreased pH, increased PCO2
Term
Lab results consistent with Respiratory alkalosis
Definition
increased pH, increased pCO2
Term
Lab results consistent with Metabolic acidosis
Definition
decreased pH, normal PCO2
Term
Lab results consistent with Metabolic alkalosis
Definition
increased pH, normal PCO2
Term
Assay of transketolase activity in blood is used to detect deficiency in
Definition
thiamine
Term
The most sensitive enzymatic indicator for liver damage from ethanol intake is
Definition
gamma-glutamyl transferase
Term
Slight increase in Alkaline phosphate and GGT, marked increase in aminotransferase and AST
Definition
acute hepatitis
Term
Slight increase in Aminotransferase and AST, marked increase in GGT and ALP
Definition
obstructive jaundice
Term
slight increase in ALK, aminotransferase, GGT, and ASP
Definition
chronic hepatitis
Term
kernicterus is an abnormal accumulation of bilirubin in
Definition
brain tissue
Term
serum anion gap is increased in patients with
Definition
lactic acidosis
Term
The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and
Definition
chloride
Term
Which of the following electrolytes is the cheif plasma cation whose main function is maintaining osmotic pressure
Definition
sodium
Term
a reciprocal relationship exists between
Definition
calcium and phosphorus
Term
at pH 7.40 what is the ratio between bicarbonate and carbonic acid
Definition
20:1

pKa = 6.1 (known)
pKa = pH - log (acid/base)
6.1 = 7.4 - log x
1.3 = log x
10^1.3 = 20/1 = 20:1
Term
acidosis and alkalosis are best defined as fluctuations in blood pH and CO2 content due to
Definition
bicarbonate buffer
Term
a common cause of respiratory alkalosis is
Definition
hyperventilation
Term
Metabolic acidosis is described as an
Definition
decrease in CO2 and PCO2 and decrease in pH
Term
respiratory acidosis is described as an
Definition
increase in CO2 and decrease in pH
Term
unless blood gas measurement are made immediately after sampling, in vitro glycolysis of the blood causes
Definition
fall in pH and rise in PCO2
Term
a hospitalized patient is experiencing increased tetany. which of the following tests should be ordered
Definition
calcium
Term
in the jaffe reaction, creatinine reacts with
Definition
alkaline picrate solution to yeild an orange-red complex
Term
bile acid concentrations are useful to assess
Definition
hepatobiliary disease
Term
the greatest activities of serum AST and ALT are seen in
Definition
acute hepatitis
Term
BeriBeri is associated with a deficiency in
Definition
thiamine
Term
Night blindness is associated with deficiency of which of the following vitamins
Definition
A
Term
Scurvy is associated with a deficiency in Vitamin
Definition
C
Term
Pellagra is associated with a deficiency in vitamin
Definition
niacin
Term
Rickets is associated with deficiency in
Definition
vitamin D
Term
in which of the following disease states is conjugated bilirubin a major serum component
Definition
biliary obstruction
Term
The creatinine clearance (mL/min) is equal to:
Definition
[urinary creatinine x volume]/ plasma creatinine
Term
Henderson-Hasselbalch equation
Definition
pH = pKa + log (salt/acid)
Term
a K level of 6.8 mEg/L, what is the first step?
Definition
check for hemolysis
Term
specimens for blood gas determination should be drawn into a syringe containing
Definition
heparin
Term
a patient suspected of having metabolic alkalosis would have which of the following laboratory findings
Definition
Co2 and pH increased
Term
which of the following is most likely to be ordered in addition to serum calcium to determine the cause of tetany
Definition
magnesium
Term
arterial blood is exposed to room air, which changes occur
Definition
elevated PO2, decreased PCO2 and elevated pH
Term
a patient with glomerulonephritis would present with the following serum results
Definition
increased BUN
Term
most automated blood gas analyzers directly measure
Definition
pH, PCO2, and PO2
Term
a pH of 7.0 represents a H+ concentration of
Definition
100 nmol/L
Term
a patient is admitted to the ER in a state of metabolic alkalosis, which of the following would be consistent with this diagnosis?
Definition
high TCO2 and increased HCO3
Term
what substance gives feces its normal color?
Definition
urobilin
Term
in monitoring Glomerular function, which of the following test has the highest sensitivity?
Definition
creatinine clearance
Term
urobilinogen is formed in the
Definition
intestine
Term
Method for bilrubin measurement
Definition
Jendrassik Grof method
Term
the most specific enzyme for acute pancreatitis is
Definition
lipase
Term
in respiratory acidosis, a compensortory mechanism is the increase in
Definition
plasma bicarbonate concentration
Term
best assay to diagnose coma due to hepatic failure
Definition
ammonia
Term
serum concentration of B12 are elevated in patients with
Definition
chronic granulocytic leukemia
Term
characteristics of malabsorption syndrome due to pancreatic insufficiency include
Definition
fecal fat greater than 10 g/day
Term
in acute pancreatitis, the relative increase in urinary amylase activity is greater than that of serum amylase activity because
Definition
there is an increased renal clearance of amylase
Term
in which of the following conditions does decreased activity of glucuronyl transferase result in increased unconjugated bilirubin and kernicterus in neonates
Definition
Crigler-Najjar syndrome
Term
a blood creatinine value of 5 mg/dL is most likely to be found with which of the following blood values?
Definition
urea nitrogen 80 mg/dL
Term
an emphysema patient suffering from fluids accumuation in the alveolar spaces is likely to be in what metabolic state?
Definition
respiratory acidosis
Term
of which of the following disease, which one is associated with the greatest elevation of lactate dehydrogenase isoenzyme I
Definition
b12 deficiency
Term
the expected blood gas results from a patient in renal failure would match the pattern of
Definition
metabolic acidosis
Term
the most important buffer pair in plasma is
Definition
bicarb/carbonic acid
Term
severe diarrhea causes
Definition
metabolic acidosis
Term
the test that evaluates renal tubular function
Definition
osmolarity
Supporting users have an ad free experience!