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Final exam
diseases
38
Microbiology
Undergraduate 1
12/12/2010

Additional Microbiology Flashcards

 


 

Cards

Term
Tetanus (lockjaw)
Definition

Bacteria: Clostridium tetani

SX: from poisoning of NS with tetanospasmin toxin - causes muscle contraction by blocking nerve signals

 

TX: treatment-Penicillin, tetaospasm antibodies, vaccination

Term
Amoebic Meningoencephalopathy
Definition

Bacteria: Naegleria- found in water systems, air conditioning, contact lens soln

SX: same as meningitis caused by bacteria, virus and fungi

TX: treatment- some drugs (early detec), but usually fatal

Term
African Sleeping Sickness
Definition

Bacteria: Trypanosoma brucei-protozoan

SX: Bite from fly turns into nasty
lesion with necrotic tissue
-Parasites in the blood create
fever, lymph nodes swell, and
patient develops headaches 
-Parasite invasion of the CNS
causes combined meningitis and
encephalitis, incl. headaches,
abnormal neurological function,
extreme drowsiness, and
eventually coma and death

TX: -never clears infection bc of abilty to evade immune system
-drugs based on progression
-insecticide to reduce occurence

Term
VCJ Disease
Definition

Bacteria: PrP prion protein

SX: irrational behavior, loss of muscle control, eventual death

TX: no known treatment

Term
Endocarditis
Definition

BACTERIA: normal microbiota Staphylococcal and others

SX: fever, fatigue, malaise, tachycardia

TX: antibiotics

Term
Infectious mononucleosis
Definition

BACTERIA: EBV

SX: severe soar throat and fever, extreme fatigue, spenomegaly

TX: focuses on relieving symptoms, no sports

Term
Bacterial Pneumonias
Definition

BACTERIA:numerous bacteria, virus and fungi

SX: lung inflammation and fluid filled alveoli and bronchioles

TX: S.pneumoniae-pcn
M.pneumoniae-TCN
K.pneumonia-Cephlosporin

Term
Tuberculosis
Definition

BACTERIA: M. tuberculosis
mycolic acid in cell wall
cord factor required for mycobacterium to cause disease

SX: minor cough and fever then later difficulty breathing, chest pain, wheezing and coughing up blood

TX: treatment of multi-drug regimen

Term
Inhalational Anthrax
Definition

BACTERIA: B. anthracis

SX: resemble cold or flu but progress to severe coughing , SOB, shock and death

TX:  various antimicrobials

Term
SARS
Definition

BACTERIA: SARS associated coronavirus

SX: high fever, head and body aches, malaise, dry cough, and eventually pneumonia

TX:

Term
Bacterial Gastroenteritis
Definition

BACTERIA: E. COLI, CAMPYLOBACTER , DH: SALMONELLOSIS

SX: inflammation of stomach or intestines due to the presence of bacteria
-nausea, vomiting, abdominal cramps and pain and diarrhea
-severe-dysentery-blood and mucous in frequent loose stools

TX: electrolyte replacement and some require antimicrobial drugs

Term
Cryptosporidiosis
Definition

BACTERIA: PROTOZOAN-CRYPTOSPORIDIUM PARVUM

SX: severe watery diarrhea, headache, muscle pain, cramping, nausea, fluid and weight loss

TX:electrolyte and fluid replacement

Term
Viral Gastroenteritis
Definition

BACTERIA: varies but includes calcicivirus(norovirus), astroviruses and rotaviruses

SX: abdomnial pain, cramping, diarrhea, nausea and vomiting

TX: SUPPORTIVE CARE

Term

Baterial Menigitis

BACTERIA: S. pneumonia-adults
N. meningitidis
L. monocytogenes-fetuses
S. agalactia-newborns

Definition

SX: sudden high fever and severe meningeal inflammation
-cranial- sever headache, vomiting, pain
-spinal-stiff neck, altered muscle control
-encephalitis-infection of brain resulting in behavior changes, coma and sometimes death

TX: VARIOUS ANTIMICROBIALS, VACCINES FOR SOME STRAINS

Term
Viral Meningitis
Definition

BACTERIA: Enterovirus

SX: skin rashes, sore throats, cold-like symptoms- typically milder than bacterial or fungal meningitis

TX: very small ssRNA vruses that lack envelope
-no specific treatment exists

Term
Leprosy (Hansen’s disease)
Definition

BACTERIA: Mycobacterium leprae - gram positive, acid fast rods

SX:grows in cooler parts of body-extremities

TX:

Term
Botulism
Definition

BACTERIA: C. botulinum

SX: progressive paralysis of all voluntary muscles (food-borne)
intestinal growth (infant)
similar to food-borne (wound)

TX: each strains produce different sets of toxins , causes muscle relaxation by blocking nerve signal transmission
-treatment-wash intestinal tract, treat with antimicrobial drugs, administer antibodies that bind to botulism toxins

Term
Smallpox
Definition

BACTERIA: Orthopoxvirus

SX: rash that develops into paules

TREATMENT: IMMEDIATE VACCINATION

Term
Chickenpox and Shingles
Definition

BACTERIA: Varicellovirus

SX: RASH

TX: SUPPORTIVE THERAPY

Term
Leishmamiasis
Definition

BACTERIA: Leishmania-protazoan-SPREAD BY FEMALE SAND FLIES

SX: LARGE PAINLESS SKIN LESIONS

TX:

 

Term
Scabies
Definition

BACTERIA: S. scabiei

SX: intense itching and localized rash at infection site

TX: treatment-miticide lotions and cleansing contaminated clothes, towels, etc.

Term
Folliculitis
Definition

BACTERIA: S. aureus

SX: red, swollen bump on the skin, can occur on base of eye(sty)

TX: treatment-methicillin

Term
Staphylococcal Scalded skin syndrome (SSSS)
Definition

BACTERIA: S. aureus

SX: cell of outer epidermis separate from one another and underlying tissue. Outer skin layers peel off in sheets

TX: no scarring b/c dermis is unaffected
-death rare
-primarily occurs in infants
-treatment-ANTIMICROBIALS

Term
Inmpetigo (Pyoderma) and Erysipelas
Definition

BACTERIA: S. aureus

SX: small red patches on face and limbs; pus-filled vesicles that itch intensely
-considered Erysipelase when spread to surrounding lymph nodes

TX: PCN AND CAREFUL CLEANING OF AA

Term
MRSA
Definition

BACTERIA: S. aureus

SX: small red bumps that turn into deep painful abscesses, serious infection migrates to bone

TX: RESISTENT TO MANY OTHER ANTIBIOTICS, VIBRAMYCIN AND/OR COMBINATION WITH OTHERS

SUPER MRSA!

Term
Necrotizing Fasciitis
Definition

BACTERIA: S. pyogenes

SX: intense pain and swelling due to digestion of muscle fascia of the bacteria
-hylauronidase break down tissue, steptokinase dissolves blood clots, phagocytic factors: M protein interferes with phagocytosis, endotoxin A causes toxemia and overactive immune response

TX: CLINDAMYCIN AND PCN AND VERY AGRESSIVE REMOVAL OF INFECTED TISSUES

Term
Acne
Definition

BACTERIA: P. ACNES-NORMAL MICROBIOTA

SX: VISUAL DETECTION OF SKIN

TX: ANTIMICROBIALS, SEBUM INHIBITORS , BLUE LIGHT

Term
Pseudomonas infection
Definition

BACTERIA: P. aeruginosa

SX: fever, chills, shock, sometimes green color due to pigment pyocyanin

TX: DIFFICULT BC P. AERUGINOSA RESISTENT TO MANY DRUGS AND DISINFECTANTS

Term
Cutaneous Anthrax
Definition

BACTERIA: B. ANTHRACIS

SX: LESION THAT FORMS FROM ESCHAR

TX: CIPRO, PCN, ERYTH

 

LIVESTOCK!

Term
Gas Gangrene
Definition

BACTERIA: Clostridium sp.
Clostridium perfringens most common

SX: pain and swelling at injury site, fever, crackling sounds and bubbles at site of infection , foul-smelling drainage, tachycardia, death

TX: SURGICAL REMOVAL OF DEAD TISSUE, ANTIBIOTICS

PREVENTION: PROPER WOUND CLEANSING

Term
Genital Candidiasis
Definition

BACTERIA: Candidia albicans

SX: itching, painful urination, soreness, thick discharge, inflammation, redness

TX: ANTIFUNGALS

Term
Oral Candidiasis-oral thrush
Definition

BACTERIA: C. albicans

SX: painful sores/lesions form in the mouth and on the tongue, dry mouth

TX: ANTIFUNGALS

NORMAL MICROBIOTA-OVERPOPULATION!

Term
Malaria
Definition

BACTERIA: Plasmodium falciparum

SX: cyclic symptoms that correlate with parasites life cycle -fever chills every 2 to 3 days

TX: CHLOROQUINE

PREVENTION-LIMIT CONTACT, PESTICIDES, PROFYLAXIS

Term
Strep Throat
Definition

BACTERIA: streptococcus

SX: fever, sore throat, can progress to scarlet or rhumatic fever

TX: BETA-LACTAMS

Term
Scarlet Fever
Definition

BACTERIA: Streptococcus

SX: sandpaper-like rash that spreads on body

TX: BETA-LACTAMS

 

ORGINATED FROM STREP THROAT

Term
Rheumatic fever
Definition

BACTERIA: Streptococcus

SX: develops from untreated strep throat, inflamation leads to joint pain, damage heart tissue

TX:

Term
Diphtheria
Definition

BACTERIA: Corynbacterium diphtheriase

SX: sore throat, oozing fluid

TX: tx-admistration of antitoxin and antibiotics
PREVENTION: VACCINE

Term
Common cold
Definition

BACTERIA: Rhinoviruses and Coronaviruses

SX: sneezing, runny nose, congestion, sore throat, malaise and cough

TX: tx-supportive care
no vaccine bc viruses change so rapidly

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