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FHDT
3 - Cellular Adaptation
12
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1st Grade
01/10/2013

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Term
Agenisis?
Definition
-Failure of even a primordium of an organ to develop
-(without creation)
Term
Aplasia?
Definition
-failure of development (growth) of the primordial structure causing organ absence
-(without growth)
-Not acquired
Term
Hypoplasia?
Definition
-Incomplete development of structure so that it does not reach adult size
-Similar to aplasia, but less severe
-Not acquired
Term
-What are the embryonic sources for a urachal fistula/cyst and Meckles?
Definition
-Urachal is from urachus from allantois
-Meckles is from the vitelline duct (to yolk sac)
Term
Choristoma?
Definition
-Neoplasia of cells in abnormal location
-Such as pancreatic cell tumor in the liver
-Cells will be normal histologically
Term
Hamartoma?
Definition
-Neoplasia in tissue of origin
-From overgrowth of mature normal cells
Term
Neoplasia?
Definition
-New growth of cells
-This would be things like choristoma, but not things like hypertrophy
Term
Atrophy?
Definition
-Decrease in either the size or number of cells resulting in decreased size grossly
-Acquired
Term
Hyperplasia?
Definition
-Structure increase due to increased number of cells
-Acquired
Term
Hypertrophy?
Definition
-Increased size of structure due to increased size of cells
-Acquired
Term
Metaplasia?
Definition
-When one type of mature cell is replaced by a different type not normal for that tissue
-Can be squamous or glandular (cuboidal or columnar) metaplasia
-Typically from irritation (bronchial columnar epithelial cells to squamous = squamous metaplasia)
Term
Dysplasia?
Definition
-Abnormality in differentiation and maturation usually with nuclear abnormalities and disordered tissue
-Cells usually immature
-Often given in thirds
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