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FDA Indications
Top 80 Drugs for Lab Midterm
61
Other
Professional
10/01/2010

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Term

 

 

Duloxetine HCl

 

FDA Indications

Definition

1.  Major depressive disorder (MDD)

2.  Management of neuropathic pain associated with diabetic peripheral neuropathy

3.  Generalized anxiety disorder (GAD)

Term
Fluoxetine HCl FDA indications
Definition

1. Depression

2. OCD

3. Bulimia nervosa

4. Panic disorder w/ or w/o agoraphoia (fear of leaving home)

Term
Sertraline HCl

FDA indications
Definition
1. Depression and OCD
2. Panic disorder w/ or w/o agoraphobia and PTSD
3. PMDD
4. SAD
Term
Amitriptyline HCl FDA indications
Definition

Relief of the sxs of depression

 

NOT RECOMMENDED FOR CHILDREN < 12 y/o

Term
Citalopram HBr

FDA indications
Definition
Depression
Term
Escitalopram Oxalate

FDA indications
Definition
Depression
Term
Trazodone HCl FDA indications
Definition

Depression w/ or w/o associated anxiety

 

NOT RECOMMENDED FOR CHILDREN < 18 y/o

Term
Venlafaxine HCl

FDA indications
Definition
1. Depression
2. GAD
3. SAD
Term
Bupropion HCl

FDA indications
Definition
Depression and prevention of seasonal major depressive episodes in pts w/ seasonal affective disorders
Term
Donepezil HCl

FDA indications
Definition
Mild, moderate & severe dementia of the Alzheimer's type
Term
Quetiapine Fumerate

FDA indications
Definition
1. Schizo
2. Depressive episodes associated w/ bipolar disorder
3. Acute manic episodes associated w/ bipolar I disorder, as monotherapy or adjunct therapy to Li or Divalproex
Term
Aripiprazole

FDA indications
Definition
1. Schizo
2. Acute manic and mixed episodes associated w/ bipolar disorder
Term
Risperidone FDA indications
Definition

1. Schizo

2. Short-term tx of acute manic or mixed episodes associated w/ Bipolar I disorder

3. Tx of irritability associated w/ autistic disorder, including sxs of aggression towards others, deliberate self-injuriousness, temper tantrums and quickly changing moods

Term
Pregabalin

FDA indications
Definition
1. Neuropathic pain associated w/ diabetic peripheral neuropathy
2. Postherpetic neuralgia
3. Adjunctive therapy for adult pts w/ partial onset seizures
4. Management of fibromyalgia
Term
Lamotrigine

FDA indications
Definition
1. Adjunctive therapy in pediatric & adult pts w/ partial seizures or generalized seizures of Lennox-Gastaut syndrome & in primary generalized tonic-clonic seizures
2. Conversion to monotherapy in adults w/ parital seizures who are receiving tx w/ a single EIAED or valproate
3. Maintance tx of Bipolar I Disorder to delay the time to occurrence of mood episodes
Term
Gapabentin FDA indications
Definition

1. Adjunctive therapy in the tx of partial sezures w/ and w/o secondary generalization in adults w/ epilepsy

2. Adjunctive therapy in the tx of partial seizures in pediatric pts age 3-12 y/o

3. Tx of postherpetic neuralgia in adults

Term
Clonazepam FDA indications
Definition
Lennox-Gastaut Syndrome (petit mal variant), akinetic and myoclonic seizures, and in pts w/ absence seizures (petit mal) who have failed to respond to succinimides
Term
Topiramate

FDA indications
Definition
1. Adjunctive and monotherapy for adults and pediatric pts ages 2-16 y/o w/ partial onset seizures, or primary generalized tonic-clonic seizures, and in pts > 2 y/o with seizures associated with Lennox-Gastaut syndrome
2. Initial monotherapy tx of partial onset or primary generalized tonic-clonic seizures in pts > 10 y/o
3. Prophylaxis of migraine HA in adults
Term
Divalproex Na

FDA indications
Definition
1. Simple (petit mal), complex absence, and complex partial seizures
2. Acute mania or mixed episodes associated with bipolar disorder, w/ or w/o psychotic features
3. Prophylaxis of migraine HAs
Term
Diazepam

FDA indications
Definition
1. Management of anxiety disorders or for the short-term relief of the sxs of anxiety
2. Withdrawal sxs of acute alcoholism
3. Relief of skeletal muscle spasm
4. Adjunct in convulsive disorderrs
5. Preoperative apprehension and anxiety
6. Endoscopy procedures
7. Cardioversion
8. Status epilepticus
Term
Alprazolam

FDA indications
Definition
1. Anxiety disorders or for the short term relief of sxs of anxiety or anxiety-associated depressive states
2. Tx of panic disorder
3. Tx of panic disorder, w/ or w/o agoraphobia
Term
Lorazepam

FDA indications
Definition
1. Anxiety disorders or for the short-term relief of the sxs of anxiety or anxiety-associated depressive states
2. Insomnia due to anxiety or transient situational stress
3. Preanesthetic medication
4. Sedation and relief of anxiety
5. Status epilepticus
6. ATIVAN INJECTION IS NOT RECOMMENDED FOR CHILDREN < 18 y/o
Term
Zolpidem Tartrate

FDA indications
Definition
Short-term tx of insomnia
Term
Carisoprodol

FDA indications
Definition
Acute, painful musculoskeletal conditions
Term
Propoxyphene Napsylate w/ Acetaminophen

FDA indications
Definition
Mild to moderate pain w/ or w/o fever

NOT RECOMMENDED FOR USE IN CHILDREN
Term
Oxycodone w/ Acetaminophen

FDA indications
Definition
Moderate or moderately severe pain
Term
Oxycodone HCl

FDA indications
Definition
Moderate to severe pain where use of an opioid analegsic is appropriate for more than a few days
Term
Hydrocodone Bitartrate w/ Acetaminophen

FDA indications
Definition
Moderate to moderately severe pain
Term
Tramadol HCl

FDA indications
Definition
1. Moderate to moderately severe pain
2. Moderate to moderately severe pain in pts who require around the clock tx for an extended period of time
Term
Naproxen

FDA indications
Definition
1. Mild to moderate pain, primary dysmenorrhea, acute tendinitis, and bursitis
2. RA, OA, and ankylosing spondylitis
3. Acute Gout

NOT RECOMMENDED IN PEDIATRIC
Term
Ibuprofen

FDA indications
Definition
1. Mild to Moderate pain and primary dysmenorrhea
2. RA, OA
3. JA
Term
Meloxicam

FDA indications
Definition
1. OA and RA
2. Pauciarticular and polyarticular course JRA
Term
Cyclobenzaprine HCl

FDA indications
Definition
Skeletal muscle spasms

NOT RECOMMENDED FOR CHILDREN < 15 y/o
Term
Fenofibrate

FDA indications
Definition
1. Adjunctive therapy to diet to reduce elevated LDL-C, Total-C, TGs and Apo B, and to increase HDL-C in adult pts w/ primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)
2. Adjunctive therapy to diet for tx of adult pts w/ hyperTG (Fredrickson Types IV and V)
3. Tx of ts w/ renal impairment
Term
Rosuvastatin Ca

FDA indications
Definition
Fredrickson Type IV, primary dysbetalipoproteinemia (Fredrickson type III), increase HDL-C in pts w/ hypercholesterlemia (heterozygous familial & nonfamilial) and mixed dyslipidemia (Type IIa & IIb)
2. Homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering txs
3. Adjunct to diet to slow the progession of atherosclerosis
Term
Atorvastatin Ca

FDA indications
Definition
1. Frederickson Type IIa, IIb, III, & IV, multiple CHD riskfactorss to reduce the risk of MI, angina, and revascularization procedures
2. Reduce the risk of non-fatal MI, fatal or nonfatal stroke, angina, revascularization, & hospitalization for CHF
3. Homozygous familial hypercholesterolemia
4. Boys & Girls 10-17 w/ heerozygous familial hypercholesterolemia if adequate diet therapy remains > 190 or > 160 AND there is a family hx of premature CVD or 2 or more CVD risk factors
Term
Lovastatin

FDA indications
Definition
1. Fredrickson Type IIa & IIb
2. Slow progression of coronary atherosclerosis in CHD pts
3. Primary prevention of CHD in pts w/o symptomatic CVD who have avg to moderately elevated TC and LDL & below avg of HDL
4. Boys & Girls 10-17 w/ heerozygous familial hypercholesterolemia if adequate diet therapy remains > 190 or > 160 AND there is a family hx of premature CVD or 2 or more CVD risk factors
Term
Simvastatin

FDA indications
Definition
1. Frederickson Type IIa, IIb, III, & IV
2. Homozygous familial hypercholesterolemia
3. Boys & Girls 10-17 w/ heerozygous familial hypercholesterolemia if adequate diet therapy remains > 190 or > 160 AND there is a family hx of premature CVD or 2 or more CVD risk factors
Term
Glipizide

FDA indications
Definition
NIDDM
Term
Glyburide

FDA indications
Definition
NIDDM
Term
Pioglitazone HCl

FDA indications
Definition
T2DM alone and in combo w/ sulfonylurea, metformin or insulin, when diet and exercise + the single agent does not result in adequate glycemic control
Term
Insulin Glargine, rDNA origin

FDA indications
Definition
T1DM and T2DM
Term
Metformin HCl

FDA indications
Definition
NIDDM
Term
Lisinopril

FDA indications
Definition
1. HTN
2. Adjunctive therapy in CHF in pts not responding adequately to diuretics and digitalis
3. Tx of hemodynamically stable pts w/in 24 h of acute MI
Term
Lisinopril w/ HCTZ

FDA indications
Definition
HTN
Term
Metoprolol Succinate

FDA indications
Definition
1. HTN
2. Long-term tx of angina pectoris
3. Tx of stable symptomatic (NYHA class ii or iii) HF of ischemic, hypertensive, or cardiomyopathic origin
Term
Metoprolol Tartrate

FDA indications
Definition
1. HTN
2. Acute MI
Term
Atenolol

FDA indications
Definition
1. HTN
2. Angina pectoris
3. Acute MI
4. Severe renal impairment
Term
Carvediolol

FDA indications
Definition
1. HTN
2. mild to moderate HF of ischemic or cardiomyopathic origin, in combo w/ digitalis, diuretics and and ACEI
3. LVEF of < 40% following MI
Term
Amlodipine Besylate

FDA indications
Definition
1. HTN
2. Chronic stable or vasospastic angina
Term
Clonidine HCl

FDA indications
Definition
HTN
Term
Diltiazem HCl

FDA indications
Definition
1. Angina pectoris due to coronary artery spasm and chronic stable angina
2. HTN
3. Temporary control of a-fib or a-flutter and rapid conversion of paroxysmal supraventricular tachy to sinus rhythm
Term
HCTZ

FDA indications
Definition
1. Adjunctive therapy in edema associated w/ CHF, hepatic cirrhosis, corticosteroid and estrogen therapy or various forms of renal dysfx
2. HTN
Term
Spironolactone

FDA indications
Definition
1. Edema due to CHF or nephrotic syndrome & cirrhosis of the liver accompanied by edema &/or ascites
2. HTN
3. Dx of primary hyperaldosteronism
4. Tx of primary hyperaldosteronism in pts unsuitable for surgery
Term
Furosemide

FDA indications
Definition
1. Edema-associated CHF, cirrhosis of the liver and renal disease
2. HTN
3. Acute pulmonary edema
Term
Tiotropium Br

FDA indications
Definition
Long-term QD maintenance tx of bronchospasm associated w/ COPD (chronic bronchitis & emphysema)
Term
Levalbuterol HCl

FDA indications
Definition
1. Bronchospasm 6-11 y/o w/ reversible obstructive airway disease
2. Bronchospasm > 12 y/o w/ reversible obstructive airway disease
3. Prevention or tx of bronchospasm in > 4 y/o reversible obstructive disease
Term
Ipratropium Br w/ Albuterol Sulfate

FDA indications
Definition
COPD
Term
Fluticasone Propionate w/ Salmeterol Xinafoate
Definition
1. Asthma
2. COPD
Term
Albuterol Sulfate

FDA indications
Definition
1. Bronchospasm w/ reversible obstructive airway disease
2. Prevention of exercise-induced bronchospasm
Term
Montelukast Na

FDA indications
Definition
1. Prophylaxis and chronic tx of asthma > 2 y/o
2. seasonal allergic rhinitis for > 2 y/o
3. Prevention of exercise-induced bronchoconstriction in pts > 15 y/o
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