Term
| Adipocyte Fat stores are broken down by what enzyme? |
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Definition
| Hormone sensitive lipase (HSL) |
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Term
| Glucagon has what effect on Hormone Sensitive Lipase? |
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Definition
Upregulates HSL via phosphorylation
insulin has opposite effect via PP1 |
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Term
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Definition
| Protein that binds to and protects triglycerides from HSL |
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Term
| What is the effect of Glucagon on Perlippin? |
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Definition
Perlippin will stop binding to triglycerides
Insulin has opposite effect via PP1 |
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Term
| How do activated fatty acids cross the inner mitochondrial membrane? |
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Definition
Carnitine acyltransferase converts activated Fatty acids into Carnitine.
FA (as carnitine) then gets uptaken into cell via Carnitine transporter (facilitated diffusion)
Carnitine is then changed bact to Fatty acid |
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Term
| What is the total amount of ATP generated from the degradation of one Palmitate molecule? |
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Definition
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Term
| Besides the mitochondria, where else does Beta-oxidation occur? |
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Definition
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Term
| How are double bonds handled in beta oxidation? |
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Definition
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Term
| Where does beta oxidation occur? |
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Definition
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Term
| What are the four steps of beta oxidation? |
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Definition
Palmitoyl-CoA -> Enoyl-CoA
via Acyl-Coa Dehydrogenase
Enoyl-CoA -> Beta-Hydroxy-acyl-Coa
via enoyl-CoA hydratase
Hydroxy-acyl-CoA -> Beta-Ketoacyl-CoA
via Beta-hydroxyacyl-CoA dehydrogenase
Beta-Ketoacyl-CoA -> Acetyl CoA
Via Acyl-CoA acetyltransferase |
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