-Atorvastatin Ca (10, 20, 40, 80 mg tab)

-High cholesterol and lipids

-10-80 mg QD

-Contra:  Liver disesase, pregnancy, nursing moms, HS to components

-Warnings:  3A4 inhibitors, grapefruit juice, cyclosporine, rifampin (inducer), oral contraceptive, wargarin; SKM effects; Liver enzyme elevation; Higher risk stroke

-S/E:  Nasopharyngitis, athralgia, diarrhea, extremety pain, UTI

-BBW?  No

-Rosuvastatin Ca (5, 10, 20, 40 mg tabs)

-Cholesterol and lipids

-5-40 mg QD

-Contra:  Liver disease, pregnancy, nursing, HS

-Warnings:  Drug interactions:  cyclosporine, gemfibrozil, lopinavir/ritonavir/atazanvir/ritonavir, courmarin, noncomitant lipid-lowering therapies; SKM effects; liver enzyme abnormalities

-S/E:  HA, myalgia, ab pain, asthenia, nausea

-BBW?  None

-Ezetimibe/Simvastatin (10/10; 10/20; 10/40; 10/80)

-HMG-CoA reductase and absorption inhibitor

-10/10-->10/40 daily; 10/80 if no evidence muscle toxicity

-Contra:  CYP3A4 inhibitors (gmfibrozil, cyclosporine, danazol); HS; acute liver disease; pregnancy; nursing

-Warnigns:  Drug interactions:  azoles; mycins; proteast inhibitors HIV; Gembibrozil, cyclosporine, donazol, aminodarone, verapamil, diltiasem, amlodipine, ranolazine, grapefruit juice; rhabomyolysis; liver enzyme elvation; hepatic impairment

-S/E:  HA, inc ALT, myalgia, URTI; diarrhea

-BBW?  No

Simvastatin (5, 10, 20, 40, 80 mg tab)

-Cholesterol and TGs

-5-40 mg QD

-Contra:  CYP3A4 inhibitors (gemfibrozil, cyclosporine, danazol); acute liver disease; pregnancy; nursing

-Warnings:  Myopathy w/ 80 mg over 65 yr olds; drug interactions (amiodarone, verapamil, dilitazem, amlodipine, ranolazine, grapefruit, chlarithromycin, ketoconazole, nefazodone, HIV protease inhibitors, erythromycin, posaconazole)

-S/E:  URTI, HA, Ab pain, Constipation, Nausea

-BBW?  No

-Ezetimibe (10 mg tab)

-Hyperlipidemia

-1 QD

-Contra:  Use with statin; pregnancy; nursing; active liver disease

-Warnings:  Not recommended for pts with moderate or severe liver disease; Drug interactions (cyclosporines, fenofibrrates, chlestryamien

-S/E:  Myalgia with stati; nasopharyngitis; URTI; Arthralgia; Diarrhea

-BBW?   No

Niacin (500, 750, 1000 mg ER tabs)

-Hyperlipidemia and MI risk reduction

-500-200 mg QD

-Contra:  Active liver disease; peptc ulcer disease; aterial bleeding

-Warnings:  Myopathy and rhabdomyolysis can occur w/ statin; hepatic toxicity; take bile acid sequestrants 4-6 h before

-S/E:  Flushing, diarrhea, N/V, increased cough

-BBW?:  No

-Fenofibrate (48 and 145 mg tab)

-Hypercholesterolemia and hypertriglyceridemia

-48-145 mg QD

-Contra: HS; hepatic or renal dysfunction; Gallbladder disease

-Warnings: Can increase efficacy of anticoagulants (caution); separate in time from bile acid sequestrants; don't use cyclosporines

-S/E:  ab pain; nausea; diarrhea; back pain; HA; Decreased liver function

-BBW?  No

-Esomeprazole (20 and 40 mg delayed release caps; 10, 20, 40 mg oral susp)

-GERD, HPI, Zollinger-ellison

-20/40 mg QD or 40 mg BID Zollinger-ellison

-Contra:  HS to ingredients

-Warnigns:  Bond fracture; atrophic gastritis; antiretroviral interactions; drugs altered by pH; drugs that use cilostazol

-S/E:  HA, diarrhea, nausea; flatulence; ab pain; constipation; dry mouth

-BBW?  No

-Rabeprazole (20 mg tab)

-GERD; H. pylori; Zollinger-Ellison

-20 mg QD

-Contra:  HS to ingredients

-Warnings:  PPIs and warfarin need to be monitored (INR increase); bone fracture; hypomagnesemia

-S/E:  none

BBW? no

-Panteprazole (20, 40 mg delayed release tab; 40 mg suspension)

-GERD; erosive esophagitis; Zollinger-ellison

-40 mg QD or BID for Zollinger-Ellison

-Contra:  HS to ingredients

-Warnings:  Atrophic gastritis, bone fracture; hypomagnesium

-S/E:  HA, diarrhea, N/V, ab pain, flatulence, dizziness, athralgia

-BBW?  No