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Extra-Articular Disease in RA
Fox
9
Medical
Graduate
12/06/2012

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Cards

Term
Hematologic
Definition
anemia
thrombocytosis
Felty's syndrome - leukopenia, splenomegaly, +/- infections and leg ulcers
Term
Nodules
Definition
subcutaneous
more common with +RF
histology - pallisading granuloma
Term
Sjorgren's Syndrome
Definition
dry eyes, mouth
lymphocytic infiltrate in salivary, lacrimal glands
+/- systemic disease
can progress to lymphoma
Term
Secondary Amyloidosis
Definition
rare
presents as proteinuria
Term
Rheumatoid Vasculitis
Definition
indolent or life threatening
severe form resembles microscopic polyarteritis
Term
Ocular
Definition
keratoconjunctivitis sicca
episcleritis
scleritis
Term
PNS
Definition
periph neuropathy
nerve entrapments
mononeuritis multiplex (due to arteritis)
Term
Pulmonary
Definition
interstitial infiltrates
BOOP
Caplans Syndrome - widespread small lung nodultes due to coal dust + RA)
Term
Serositis
Definition
pleural effusions - low glucose, variable WBC, low complement, high protein
pericardial effusions - usually occult, occasionally leads to tamponade or constriciton
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