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Exam 4 Chemistry Review/Study Questions Part 4
Review / Study Questions
57
Chemistry
Undergraduate 3
04/01/2015

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Term
What is the formula for the % Tf Saturation?
Definition
(Total Iron / TIBC ) x 100
Term
True or False:
Ferritin levels in serum will decrease BEFORE total iron content is depressed
Definition
True
Term
What does Total Serum Iron Measure?
Definition
Iron bound to Tf
Term
What is Transferrin often measured by?
Definition
Nephelometry
Term
What is Total Iron Binding Capacity a measure of?
Definition
Capacity of transferrin to bind more iron
Term
Usually Tf is what percent saturated with iron?
Definition
20-50%
Term
What is the formula to calculate TIBC knowing Tf?
Definition
TIBC = Tf x 1.25
Term
True or False:
You can not calculate TIBC if Tf<70
Definition
True
Term
True or False:
You can not calculate % Tf Saturation is TIBC<5
Definition
True
Term
Name the condition associated with the following:
Iron - Decreased
Ferritin - Decreased
Transferrin - Increased
RBC Count - Decreased
H&H - Decreased
MCHC - Decreased
Micro/Hypo
Definition
IDA
Term
Name the condition associated with the following:
Iron - Increased
Ferritin - Increased
Transferrin - Decreased
Hemochromatosis
Definition
Iron Overload
Term
Name the condition associated with the following:
Iron - Decreased
Ferritin - Normal to Increased
Transferrin - Decreased
Definition
Anemia of Chronic Disease
Term
What is the term used to describe hereditary iron overload disease?
Definition
Hemochromatosis
Term
What can you use to treat Iron Overload?
Definition
Therapeutic phlebotomy or chelators
Term
Which iron disorder is connected to the following:
Cancer
Hogkins
SLE
Renal failure with decreased erythropoietin
Definition
Anemia of Chronic Disease
Term
Given the following Determine the Iron Disease State:
Total Fe - Decreased
Ferritin - Decreased
Transferrin - Increased
TIBC - Increased
% Saturation - Decreased
Definition
IDA
Term
Given the following Determine the Iron Disease State:
Total Fe - Increased
Ferritin - Increased
Transferrin - Decreased
TIBC - Decreased
% Saturation - Increased
Definition
Hemochromatosis
Term
Given the following Determine the Iron Disease State:
Total Fe - Decreased
Ferritin - Normal to Increased
Transferrin - Decreased
TIBC - Decreased
% Saturation - Decreased
Definition
Anemia of Chronic Disease
Term
Match the trace element with the deficiency results:
o Hypochromic anemia
o Bone malformation
o Menke's syndrome
o Wilson's disease
Definition
Copper
Term
Match the trace element with the deficiency results:
o Impaired immunity and wound healing
o Impotence
o Growth retardation
oSensory alterations
Definition
Zinc
Term
Match the trace element with the deficiency results:
o Megaloblastic anemia
Definition
Cobalt
Term
Match the trace element with the deficiency results:
o Reduced glucose tolerance
Definition
Chromium
Term
Match the trace element with the deficiency results:
o Bone defects and stunted growth
o Clotting disorders
o Epilepsy
Definition
Manganese
Term
Match the trace element with its Functions:
Erythropoiesis
Cellular respiration
Skeletal development
Nucleic acid/protein synthesis
Collagen formatio
Definition
Copper
Term
Match the trace element with its Functions:
Enzyme structure
RNA/DNA synthesis
Sensory development
Growth
Wound healing
Immune response
Definition
Zinc
Term
Match the trace element with its Functions:
Constituent of Vit B12
Needed for folate metabolism
Definition
Cobalt
Term
Match the trace element with its Functions:
“Glucose Tolerance Factor”,
increases effects of insulin
Definition
Chromium
Term
Match the trace element with its Functions:
Enzyme activator
Reproductive function
Bone and tissue formation
Definition
Manganese
Term
What is the formula of the Henderson-Hasselbalch Equation?
Definition
pH = pK' + log (Buffer/Acid)
Term
Define the following:
Acid
Definition
Yield hydrogen ions (H+) when dissolved in H2O
Primary sources in the blood:H+, H2CO3 (carbonic acid) and pCO2
Term
Define the following:
Base
Definition
Yield hydroxyl ions (OH-)
Primary source in the blood: HCO3 (bicarbonate)
Term
Define the following:
Buffer
Definition
A system consisting of a weak acid and
a weak base that resists pH changes
Term
Great quantities of H+ come from where?
Definition
Cell metabolism and food digestion
Term
Define the following:
Total CO2
Definition
The sum of the various CO2-containing substances in plasma
Term
Acidemia/acidosis = arterial pH below
Definition
7.35
Term
Alkalemia/alkalosis = arterial pH above
Definition
7.45
Term
What are the various CO2-containing substances in plasma?
Definition
Dissolved CO2 gas from cellular respiration (pCO2)
Carbonic acid (H2CO3)
Bicarbonate ion (HCO3-)
Term
Total CO2 = ______ mmol/L
Definition
23-29
Term
HCO3 = ________mmol/L
Definition
22-26
Term
True or False:
Bicarbonate-Carbonic Acid System is the principle buffering system
Definition
True
Term
Normally, the ratio of HCO3 to CO2 is _____
Definition
20:1
Term
A fall in the ratio of HCO3 to CO2 results in what?
Definition
Acidosis
Term
A rise in the ratio of HCO3 to CO2 results in what?
Definition
Alkalosis
Term
What 2 organs will respond to restore the 20:1 HCO3 to CO2 ratio?
Definition
Lungs and/or Kidneys
Term
True or False:
If plasma becomes acidic, HCO3 can diffuse out of the RBC to buffer the blood
Definition
True
Term
As HCO3 diffuses out of the RBC to buffer the blood, what moves in?
Definition
Chloride
Term
____ventilation: More CO2 is lost and blood becomes alkaline
Definition
Hyperventillation
Term
____ventilation: CO2 accumulates and blood becomes acidic
Definition
Hypoventilation
Term
True or False:
The response time to ventilation changes occurs within seconds
Definition
True
Term
True or False:
Tubules will excrete or retain acid (H+) or alkaline (HCO3)
Definition
True
Term
When H+ is retained by the kidneys, what is excreted?
Definition
Na+
Term
When Na+ is retained by the kidneys, what is excreted?
Definition
H+
Term
As H+ is excreted or Retained by the kidneys, what moves with it?
Definition
K+
Term
Correction of pH may take how much time when regulated by the kidneys?
Definition
2-4 days
Term
What is it called when:
pH has returned to normal, other 2 parameters are abnormal
Definition
Fully Compensated
Term
What is it called when:
the pH and 1 other parameter are abnormal
Definition
Uncompensated
Term
What is it called when:
All 3 parameters are abnormal
Definition
Partially Compensated
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