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Exam 4 Chemistry Review/Study Questions Part 3
Review / Study Questions
53
Chemistry
Undergraduate 3
04/01/2015

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Term
Match the Electrolyte Imbalance with the following:
Aldosterone deficiency
Water retention or water intoxication
Potassium deficiency (kidneys will retain K, excrete Na)
Diuretics
Nausea, vomiting, weakness, headache, seizures, coma
Definition
Hyponatremia
Term
Match the Electrolyte Imbalance with the following:
Dehydration-#1 cause
Diabetes insipidus
Increased Na intake
Hypothalmic disease or head trauma
Decreased thirst (ex. Hypothalamic dz, elderly, infants, mentally impaired)
Mental changes, restlessness, twitching, fever, thirst, nausea
Definition
Hypernatremia
Term
Match the Electrolyte Imbalance with the following:
GI loss
Urinary loss (renal disease)
Insulin overdose (K and gluc move into cells)
Alkalosis (as H moves out to maintain pH, K and Na move in)
Muscle weakness, paralysis, arrhythmia
Definition
Hypokalemia
Term
Match the Electrolyte Imbalance with the following:
Red cell lysis / muscle injury
Chemotherapy and leukemia
Diabetes: low insulin causes serum buildup of K
Acidosis (H moves in, K moves out)
Muscle weakness, tingling, numbness, confusion, arrhythmias
Definition
Hyperkalemia
Term
Match the Electrolyte Imbalance with the following:
Prolonged vomiting
Aldosterone deficiency (along with Na)
Definition
Hypochloremia
Term
Match the Electrolyte Imbalance with the following:
Bicarbonate loss (acidosis)
Definition
Hyperchloremia
Term
Match the Electrolyte Imbalance with the following:
Increased Levels of Bicarbonate HCO3-
Definition
Metabolic alkalosis
Term
Match the Electrolyte Imbalance with the following:
Decreased Levels of Bicarbonate HCO3-
Definition
Metabolic acidosis
Term
Match the Electrolyte Imbalance with the following:
Hypoparathyroidism
Vitamin D deficiency
Albumin deficiency ( affects total calcium only)
Cardiac irregularities, tetany and seizures
Definition
Hypocalcemia
Term
Match the Electrolyte Imbalance with the following:
Hyperparathyroidism
Malignancies, Multiple myeloma
Drowsiness, depression, coma
Definition
Hypercalcemia
Term
Cardiac arrest may result in both hypo
and hyper_____
Definition
kalemia
Term
By what 3 mechanisms regulate Potassium?
Definition
1. Aldosterone, in exchange for Na
2. Na-K pump
3. insulin, which promotes the entry of K into cells
Term
Match the Electrolyte Imbalance with the following:
Poor diet / starvation
Malabsorption
Hyperparathyroidism and other dzs with
Increased Calcium
-kidneys excrete Mg to balance cations
Arrhythmias, tetany, psychiatric symptoms
Definition
Hypomagnesemia
Term
Match the Electrolyte Imbalance with the following:
Renal failure, especially in combination with antacids
Bradycardia (slow heartbeat), decreased reflexes, lethargy
Definition
Hypermagnesemia
Term
Match the Electrolyte Imbalance with the following:
Common in hospitalized patients
Diabetic ketoacidosis
Hyperparathyroidism
Malaise, confusion, coma due to ATP depletion
Definition
Hypophosphatemia
Term
Match the Electrolyte Imbalance with the following:
Renal failure
Avoid hemolysis
Definition
Hyperphosphatemia
Term
What tubes should you avoid when determining Calcium levels?
Definition
EDTA
Term
Calcium exists in the plasma as what?
Definition
*Free calcium ions or “ionized calcium”
*Bound to Albumin or other anions
Term
As Calcium Increases, what happens to PO4?
Definition
Decreases
Term
As Calcium Decreases, what happens to PO4?
Definition
Increases
Term
As PTH Increases, what happens to PO4?
Definition
Decreases
Term
True or False:
Lactate (Lactic acid) is used to monitor critically ill patients for severity of illness and prognosis
Definition
True
Term
What are the sample requirements when testing for Lactate (Lactic Acid)?
Definition
Don't use a tourniquet
Use heparinized blood or fluoride on ice
Term
What is the formula for the Anion Gap?
Definition
(Na + K) - (Cl + HCO3)
Term
What is the reference range for (Na + K) - (Cl + HCO3)?
Definition
10-20 mmol/L
Term
What is the reference range for Na - (Cl + HCO3)?
Definition
7-16 mmol/L
Term
What is the cause of a Decreased AG?
Definition
Rare, usually instrument error
Term
What is the cause of an Increased AG?
Definition
Lactic acidosis
Alcohol or salicylate intoxication
Ketoacidosis (diabetes / starvation)
Renal failure
Term
What is the following considered:
The presence of low blood pH, elevated AG, and elevated ΔOsmo (>15)
Definition
Medical Emergency
Term
As a QC tool, an increased AG on a normal sample may indicate what?
Definition
Instrument Error
Term
Give the acid-base disorder (uncompensated) associated with the following results:
Increased pH, Increased HCO3
Definition
Metabolic Alkalosis
Term
Give the acid-base disorder (uncompensated) associated with the following results:
Decreased pH, Increased CO2
Definition
Respiratory Acidosis
Term
Give the acid-base disorder (uncompensated) associated with the following results:
Decreased pH, Decreased HCO3
Definition
Metabolic Acidosis
Term
Give the acid-base disorder (uncompensated) associated with the following results:
Increased pH, Decreased CO2
Definition
Respiratory Alkalosis
Term
Match the cause with the likely acid-base disorder:
Pneumonia
Definition
Respiratory acidosis
Term
Match the cause with the likely acid-base disorder:
Anxiety
Definition
Respiratory alkalosis
Term
Match the cause with the likely acid-base disorder:
Diabetic ketoacidosis
Definition
Metabolic acidosis
Term
Match the cause with the likely acid-base disorder:
Emphysema
Definition
Respiratory acidosis
Term
Match the cause with the likely acid-base disorder:
Vomiting
Definition
Metabolic alkalosis
Term
Match the cause with the likely acid-base disorder:
Morphine or alcohol
Definition
Respiratory acidosis
Term
Match the cause with the likely acid-base disorder:
Tissue hypoxia
Definition
Metabolic acidosis
Term
Match the cause with the likely acid-base disorder:
Salicylate overdose
Definition
Metabolic acidosis & Respiratory alkalosis
Term
Match the cause with the likely acid-base disorder:
Diuretics
Definition
Metabolic alkalosis
Term
What is the preferred anticoagulant for arterial blood gas collection?
Definition
Heparin
Term
Are there any other special handling requirements for Blood Gas Analysis?
Definition
Cap the needle, put on ice, test within 30 min
Term
List the effect of an air bubble and a delay in testing on ABG results for:
pO2
Definition
Air Bubble - Increased
Delay in Testing - Decreased
Term
List the effect of an air bubble and a delay in testing on ABG results for:
pCO2
Definition
Air Bubble - Decreased
Delay in Testing - Increased
Term
List the effect of an air bubble and a delay in testing on ABG results for:
pH
Definition
Air Bubble - Increased
Delay in Testing - Decreased
Term
What methodology measures current that flows through a system?
Definition
Amperometry
Term
Name the blood gas commonly measured by this method
Definition
O2
Term
What methodology measures the voltage difference between 2 electrodes?
Definition
Potentiometry
Term
What are the two types of electrodes used in the Potentiometry system?
Definition
Reference and Sample (indicator)
Term
Name the analytes commonly measured by the Potentiometry system method
Definition
pH, electrolytes, pCO2
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