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| TFIID collaborates with TFIIA to bind to the TATA box. |
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| Epitope tagging is an efficient way to immunoprecipate to isolate an entire polymerase complex. |
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| One hypothesis explaining the mechanism of repression of the lac operon states that the repressor binds the operator and blocks access by the polymerase to the adjacent promoter. |
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| The following is an example of a cis-dominant mutation: I-d O+ Z+ Y+ A- |
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| Roeder and Rutter showed that there are four polymerases operating in the eukaryotic cell. |
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| RNA polymerase prevents the binding of TFIIF to the promoter region. |
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| Eukaryotic ribosomal RNA genes are transcribed by RNA polymerase II. |
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| A promoter region replacing the TATA box with the ICIC box will not bind to TFIID. |
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| Recent experimental evidence has shown that only one operator sequence is needed for maximal expression. |
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| In the absence of glucose there will be a rapid accumulation of lactose in the following mutant: I- Oc Z+ Y- and I-O+ Z+ Y- |
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| If an operon is under negative control it means that the operon is never operational. |
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| cAMP level is increased by the presence of high levels of glucose. |
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