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Exam 2 - Chapter 5
How neurons communicate and adapt
40
Psychology
Undergraduate 2
02/19/2009

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Term
epinephrine
Definition
Chemical messenger that acts as a hormone to mobilize the body for fight or flight during times of stress and as a neurotransmitter in the central nervous system.
Term
Norepinephrine
Definition
Neurotransmitter found in the brain and in the  parasumpathetic division of the autonomic nervous system
Term
Neurotransmitter
Definition
Chemical release by a neuron onto a target with an excitatory or inhibitory effect
Term
Dopamine
Definition
Amine neurotransmitter that plays a role in coordinating movement in attention and learning and in behaviors that are reinforcing
Term
Synaptic vessicle
Definition
Organelle consisting of a membrane structure that encloses a quantum of neurotransmitters
Term
Synaptic cleft
Definition
gap that seperates the presynamptic membrane from the postsynaptic membrane
Term
Chemical synapse
Definition
Junction where messenger molecules are released when stimulated by an action potential
Term
Presynaptic membrane
Definition
Membrane on the transmitter outpute side of a synapse
Term
Postsynaptic membrane
Definition
Membrane on the transmitter inpute side of a synapse
Term
Storage granule
Definition
Membranous compartment that holds several vessicles containing a neurotransmitter
Term
Electrical synapse
Definition
Fused presynaptic and postsynaptic membrane that allows an action potential to pass directly from one neuron to the next
Term
Transporter
Definition
Protein molecule that pumps substances across a membrane
Term
Transmitter-activated receptor
Definition
Protein embedded in the membrane of a cell that has a biniding site for a specific neurotransmiter
Term
autoreceptor
Definition
self-receptor in a neural membrane that responds to the transmitter that the neruon releases
Term
Quantum
Definition
Quantitiy equivalent to the contents of a single synaptic vesicle that produces a just observable change in the postsynaptic electric potential
Term
Reuptake
Definition
deactivation of a neurotransmitter when membrane transporter protiens bring the transmitter back into the presynaptic axon terminal for subsequent reuse
Term
Small molecule transmitter
Definition
class of quick acting neurotransmitters synthesized in hte axon terminal from products derived from the diet
Term
Rae-limiting factor
Definition
Any enzyme that is in limited supply, thus restricting the pace at which a chemical can be synthesized
Term
Glutamate
Definition
Amino acid neurotransmitter that excites neurons
Term
Gamma-aminobutyric acid (GABA)
Definition
Amino acid neurotransmitter that inhibits neurons
Term
Neuropeptide
Definition
A multifuctional chain of amino acids taht acts as a neurotransmitter; synthesized from mRNA on instructions from the cell's DNA
Term
Nitric oxide
Definition
Acts as a chemical neurotranmitter gas - for example, to dilate blood vessels, aid digestion, and activate cellular metabolism
Term
Carbon monoxide
Definition
Acts as a neurotranmitter gas in the activation of cellular metabolism
Term
Ionotropic receptor
Definition
Embedded membrane protein with two parts:  a binding site for a neurotransmitter and a pore that regulates ion flow to directly and rapidly change membrane coltage
Term
Metabotropi receptor
Definition
Embedded membrane protein, with a binding site for a neurotransmitter but nopore, linked to a G protein that can affect other receptors or act with second messengers to affect other cellular processes
Term
G protein
Definition
Family of guanyl nuleotide-binding proteins coupled to metabotropic receptors that, when activated, bind to other proteins
Term
Second messenger
Definition
Activated by a neurotransmitter (the first messenger) a chemical that carries a message to initiate a biochemical process
Term
Cholinergic neuron
Definition
neuron that uses acetylcholine as a its main neurotransmitter
Term
Nocotine ACh receptor
Definition
Ionotropic receptro at which acetylcholine and the drug nicotine act as ligands to activate the flow of ions through the receptor pore
Term
Activating system
Definition
Neural pathways taht coordinate brain activity through a single neurotranmitter; cell bodies are located in a nucleus in the brainstem and axons are distributed throu a wide region of the brain
Term
Alzheimers disease
Definition
Degenrative brain disorder; first appears as progressive memory loss and later develops into generalized dementia
Term
Schizophrenia
Definition
behavioral disorder characterized by delusions, hallucinations, disorganized speech, blunted emotion, agitation or immobility, and a host of associated symptoms
Term
Noradrenergic neuron
Definition
From adrenaline, Latin for epinephrine; a neuron containing norpinephrine
Term
Obsessive-compulsive disorder
Definition
Behavioral disorder characterize by compulsively repeated actcs and repetitive often unpleasent thoughts
Term
Learning
Definition
Relatively permanent change in behabior that results from experience
Term
Neuroplasticity
Definition
The nervous systems potential for neurophysical or neurochemical change that enhances its adaptability to enviromental change and its ability to compensate for injury
Term
Habituation
Definition
learning behavior in which a response to a stimulus weakens with repeated stimulus presentations
Term
Sensitization
Definition
Learning behavior in which the response ot a stimulus strenthens with repeated presentations of that stimuls because the stimuls is novel or becuase the stimulus is stronger than normal - for example after habituation has occured
Term
Associative learining
Definition
linkage of two or more unrelated stimuli to elicit a behavioral response
Term
Long term potentiation
Definition
In response to stimulation at a synapse, changed amplitude of an excitator postsynaptic potential that last for horus to days or longer and plays a prt in associative learning
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