Term
| If a person has an H gene then which antigen is on their red blood cells? |
|
Definition
| fucsyl transferases which adds L-fuctose to the base of the immunodominant structure of H antigen |
|
|
Term
| If a person has an A gene then which antigen is on their red blood cells? |
|
Definition
| galactosaminyl-transferase that adds N-acetyl-galactosamine to the H (L-fructose) base |
|
|
Term
| If a person has an B gene then which antigen is on their red blood cells? |
|
Definition
| galactosyl-transferase adds D-galactose to the H (L-fructose) base |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Characteristics of the ABO antibodies |
|
Definition
| naturally occurring, anti-b (A blood), anti-a (B blood), both (O blood) or neither (AB blood), Attack foreign antigens on the RBC surfaces |
|
|
Term
| Distinction and practical importance between A1 and weaker subgroups of A. |
|
Definition
| A1 gene allows for more A antigens to be expressed on the RBC surface, A2 genes do not code for as many enzymes so not as many antigens are A |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Steps to be taken when forward and reverse do not match? |
|
Definition
| order a new specimen, wash the specimen (retest), look at patient file, determine the cause of the discrepancy |
|
|
Term
| Who discovered the ABO blood group system and when did he discover it? |
|
Definition
|
|
Term
| What is Landsteiner's Rule? |
|
Definition
reciprocal antibodies are consistently and predictably present in the sera of normal people whose rbcs lack the corresponding antigen
If you have the antibody you CANNOT have the antigen |
|
|
Term
|
Definition
| A antigens, Anti-B antibody |
|
|
Term
|
Definition
| B antigens, Anti-A antibody |
|
|
Term
|
Definition
| A and B antigens, no antibodies |
|
|
Term
|
Definition
| neither antigen, anti-a and anti-b antibodies |
|
|
Term
| What does ABO inheritance follow? |
|
Definition
|
|
Term
| What is the most frequent blood type? |
|
Definition
|
|
Term
| Why do babies give weaker ABO results? |
|
Definition
| because antigens are not fully developed |
|
|
Term
| Where are ABO antigens located? |
|
Definition
| RBCs, lymphs, platelets, tissue cells, bone marrow and solid organs |
|
|
Term
| Are antigens direct products of genes? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Immunodominant structure of H antigen |
|
Definition
|
|
Term
| Immunodominant structure of A antigen |
|
Definition
|
|
Term
| Immunodominant structure of B antigen |
|
Definition
|
|
Term
| An emergency transfusion of packed RBC's is required for a premature newborn. What ABO type should be issued for transfusion? |
|
Definition
|
|
Term
| Which of the following is true of ABO antibodies? |
|
Definition
| They are "naturally occuring" antibodies |
|
|
Term
|
Definition
| OO offspring with O phenotype not possible |
|
|
Term
| Individuals of blood group O have: |
|
Definition
| The isoagglutinins A and B in their plasma |
|
|
Term
| Which phenotype is seen more frequently in the "white" population than the "black" population |
|
Definition
|
|
Term
| Given a mother of Group O and an infant of Group B, which of the following blood groups of the questionable father would eliminate his paternity? |
|
Definition
|
|
Term
| Which of the following ABO blood groups contains the least amount of H substance?\ |
|
Definition
|
|