Term
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Definition
Direct-acting MUSCARINIC agonists
AND
Direct-acting NICOTINIC agonists |
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Term
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Definition
Direct-acting MUSCARINIC agonists
BBB = Bethanechol stimulates Bowels and Bladder
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Term
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Definition
| Direct-acting MUSCARINIC agonists |
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Term
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Definition
| Direct-acting MUSCARINIC agonists |
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Term
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Definition
| Direct-acting MUSCARINIC agonists |
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Term
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Definition
Direct-acting NICOTINIC agonists
Activator at low doses, Blocker (antagonist) at high doses
Smoking cessation
SE = hypertension, tachycardia, nausea/vomiting |
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Term
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Definition
| Acetylcholinesterase regenerators |
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Term
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Definition
Indirect cholinergic agonists (reversible) PNS
MG |
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Term
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Definition
Indirect cholinergic agonists (reversible) PNS
Acute glaucoma, bowel atony, reversal of atropine poisoning |
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Term
| Neostigmine/pyridostigmine |
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Definition
Indirect cholinergic agonists (reversible) PNS
MG, urinary retension |
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Term
| Donepezil, galantamine, rivastigmine, tacrine |
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Definition
Indirect cholinergic agonists (reversible) CNS
Alzheimer dz, especially dementia |
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Term
| Echothiophate, isoflurophate, parathion, malthion |
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Definition
Indirect cholinergic agonists (irreversible)
used as nerve gases in wars. Occasionally used for esotropia.
Toxicity = SLUDGE = Salivation, Lacrimation, Urination, Diaphoresis, GI motility (diarrhea), Emesis |
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Term
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Definition
| Cholinergic blockers (antagonists) Muscarinic |
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Term
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Definition
| Cholinergic blockers (antagonists) Selective Muscarinic |
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Term
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Definition
| Cholinergic blockers (antagonists) Selective Muscarinic |
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Term
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Definition
Cholinergic blockers (antagonists) Neuromuscular (Nicotinic)
Skeletal mm relaxation. SE = histamine release |
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Term
| Pancronium, atracurium, vancuronium, rocuronium, |
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Definition
| Cholinergic blockers (antagonists) Neuromuscular (Nicotinic) |
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Term
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Definition
Cholinergic blockers (antagonists) Neuromuscular (Depolarizing NMB)
Adjuvant to general anesthesia |
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Term
| Nicotine, hexamethonium, mecamylamine, trimethaphan |
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Definition
Cholinergic blockers (antagonists) Neuromuscular (Ganglionic Blockers)
smoking cessation. SE = all ganglionic suppression |
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Term
| Phenylephrine, methoxamine, clonidine, methyldopa |
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Definition
| Direct adrenergic agonists, alpha selective |
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Term
| Albuterol, dobutamine, isoproterenol, metaproterenol, terbutaline |
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Definition
| Direct adrenergic agonists, beta selective |
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Term
| Catecholamines (dopamine, neurepinephrine, epinephrine) |
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Definition
| Direct adrenergic agonists, non-selective |
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Term
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Definition
| Indirect-acting adrenergic agonists |
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Term
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Definition
| Indirect-acting adrenergic agonists |
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Term
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Definition
Indirect-acting adrenergic agonists
NATURAL not synthesized, found in fermented foods. If taking MAO inhibitors, body cannot synthesize tyramine -> decreased NE release |
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Term
| Ephedrine, Pseudoephedrine, phenylephedrine, metaraminol |
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Definition
| Mixed-acting adrenergic agonists (activate both alpha and beta receptors) |
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Term
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Definition
COMT inhibitors (adrenergic receptors) Parkinson’s dz
(Al -capone got COMT!) |
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Term
| Selegiline, phenelzine, tranylcypromine |
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Definition
MAO inhibitors (adrenergic receptors)
Parkinson’s dz, depression |
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Term
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Definition
| Reuptake inhibitors (adrenergic receptors) |
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Term
| Prazosin, doxazosin, terazosin, tamsulosin |
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Definition
Alpha-1 adrenergic antagonists (blockers)
(ending in -osin = alpha-1 blocker) |
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Term
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Definition
| Alpha-2 adrenergic anatagonists (blockers) |
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Term
Phenoxybenzamine
Pentolamine |
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Definition
| Non-selective Alpha adrenergic antagonists (blockers) |
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Term
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Definition
Beta-1 adrenergic antagonists (blockers) hypertension, safer to use with bronchospasms
(endings in -olol = beta blockers) |
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Term
| Esmolol, metoprolol, acebutolol, |
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Definition
| Beta-1 adrenergic antagonists (blockers) |
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Term
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Definition
Non-selective Beta adrenergic antagonists (blockers)
hypertension, thyroid storm, NOT SAFE to use with bronchospasm (asthma) |
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Term
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Definition
| Non-selective (both beta and alpha) adrenergic antgonists (blockers) |
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